scholarly journals Massive pressure amplification by stimulated contraction of mesoporous frameworks

2021 ◽  
Author(s):  
Volodymyr Bon ◽  
Simon Krause ◽  
Irena Senkovska ◽  
Nico Grimm ◽  
Dirk Wallacher ◽  
...  
Keyword(s):  
Pressure Amplification

scholarly journals Pulse Pressure Amplification and Risk of Cardiovascular Disease

2008 ◽  
Vol 21 (4) ◽  
pp. 388-392 ◽  
Author(s):  
M.-E. Nijdam ◽  
Y. Plantinga ◽  
H. T. Hulsen ◽  
W. J. W. Bos ◽  
D. E. Grobbee ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Pulse Pressure ◽  
Pressure Amplification

WEAK CARDIAC EJECTION PATTERNS RESULTS IN INCREASED CENTRAL TO PERIPHERAL PULSE PRESSURE AMPLIFICATION

2011 ◽  
Vol 29 ◽  
pp. e484-e485
Author(s):  
B. Westerhof ◽  
B. Van Den Bogaard ◽  
B. J. Van Den Born ◽  
J. P. Van Den Wijngaard ◽  
F. Mattace-Raso
Keyword(s):  
Pulse Pressure ◽  
Pressure Amplification ◽  
Peripheral Pulse

scholarly journals Effects of smoking on central blood pressure and pressure amplification in hypertension of the young

2016 ◽  
Vol 21 (5) ◽  
pp. 422-428 ◽  
Author(s):  
Francesca Saladini ◽  
Elisabetta Benetti ◽  
Claudio Fania ◽  
Lucio Mos ◽  
Edoardo Casiglia ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Central Blood Pressure ◽  
Pressure Amplification

P2.08 CENTRAL-TO-PERIPHERAL BLOOD PRESSURE AMPLIFICATION: INVASIVE VALIDATION OF TWO DEVICES (SPHYGMOCOR AND OMRON HEM9000AI)

2012 ◽  
Vol 6 (4) ◽  
pp. 165
Author(s):  
G. Pucci ◽  
F. Battista ◽  
S. Notaristefano ◽  
C. Cavallini ◽  
E. Mannarino ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Peripheral Blood ◽  
Pressure Amplification ◽  
Peripheral Blood Pressure

Abstract MP100: Arterial Stiffness and Pressure Amplification Associated with Markers of Cerebral Microvascular Disease: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)

Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Priya Palta ◽  
Jingkai Wei ◽  
Michelle Meyer ◽  
Melinda C Power ◽  
Jennifer A Deal ◽  
...  
Keyword(s):  
Older Adults ◽  
Arterial Stiffness ◽  
Pulse Pressure ◽  
Aortic Stiffness ◽  
Brain Mri ◽  
Intracranial Volume ◽  
Sampling Weights ◽  
Arterial Stiffening ◽  
Lacunar Infarcts ◽  
Pressure Amplification

Introduction: Small vessel disease is associated with decreased cognitive function, possibly differential by race. Age-related central arterial stiffening increases pulsatility resulting in hypoperfusion, microvascular damage and remodeling in the brain, potentially impairing cognition. We examined if arterial stiffness and pressure amplification are associated with lacunar infarcts and greater volumes of white matter hyperintensities (WMH) in a sample of Caucasian and African American (AA) older adults. Methods: We analyzed a cross-sectional sample of ARIC participants aged 67-90 years (n=1486) from visit 5 (2011-2013), with brain magnetic resonance imaging (MRI). The Omron VP-1000 Plus was used to measure aortic stiffness (carotid-femoral pulse wave velocity [cfPWV]) and pressure amplification measures (pulse pressure amplification [PPA], central pulse pressure [cPP], and estimated central systolic blood pressure [cSBP]). Aortic stiffness and pressure amplification were dichotomized at race-specific 25th percentile cut points. Brain MRI using 3D-1.5T equipment quantified the presence of lacunar infarcts and volumes of WMH following a standardized protocol. Logistic regression, adjusted for age, sex, education, ApoE4, heart rate, smoking and body mass index, was used to quantify the odds of lacunar infarcts in participants with high vs. low cfPWV, cPP, cSBP, and low vs. high PPA. Linear regression models, additionally adjusted for intracranial volume, estimated the difference in log-transformed volumes of WMH among participants with high vs. low cfPWV, cPP, cSBP, and low vs. high PPA. Probability sampling weights for an MRI were included to allow for generalizability to the full visit 5 cohort. Results: Among the 1486 participants with a brain MRI (mean age: 76, 41% male, 26% AA), measures of aortic stiffness and pressure amplification were associated with lacunar infarcts in Caucasians, but not in AAs. Caucasian participants with a high cfPWV had greater odds of lacunar infarcts (Odds Ratio [OR] =2.02, 95% confidence interval [CI]: 1.23, 2.20). Caucasians with high cSBP had higher odds of lacunar infarcts (OR=1.72, 95% CI: 1.10, 2.69). In Caucasians, high cfPWV was associated with a 21% (95% CI: 6, 38) greater volume of WMH as compared to a low cfPWV; high cSBP was associated with a 28% (95% CI: 14, 45) greater volume of WMH compared to a low cSBP. In AAs, high cfPWV was associated with a 32% (95% CI: 7, 62) greater volume of WMH as compared to low cfPWV. Cerebral microvascular imaging markers did not differ quantitatively with measures of PPA and cPP. Conclusions: Central arterial stiffening and pressure amplification are plausible microvascular contributors to cognitive aging, providing new information on modifiable pathways for previously observed associations between cardiovascular disease risk factors and the rates of cognitive decline and dementia among older adults.

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