New organotin(IV) derivatives of dipeptides as models for metal-protein interactions:in vitro anti-tumour activity

2003 ◽  
Vol 17 (5) ◽  
pp. 305-314 ◽  
Author(s):  
Mala Nath ◽  
Sandeep Pokharia ◽  
Xueqing Song ◽  
George Eng ◽  
Marcel Gielen ◽  
...  
Keyword(s):  
Anti Tumour Activity ◽  
Derivatives Of ◽  
Tumour Activity

Anti-mesodermal Activity of a Nitrogen Mustard Derivative

Development ◽  
1963 ◽  
Vol 11 (4) ◽  
pp. 689-696
Author(s):  
A. Jurand
Keyword(s):  
Nitrogen Mustard ◽  
Saline Solution ◽  
Embryonic Tissues ◽  
Anti Tumour Activity ◽  
Stage 4 ◽  
Cent Saline ◽  
Specific Selectivity ◽  
Walker Carcinoma ◽  
Derivatives Of ◽  
Tumour Activity

Amongst the numerous derivatives of nitrogen mustard that have been tested for their anti-tumour activity on Walker carcinoma by Danielli and his collaborators (1961), (Cl—CH2—CH2)2: N—C6H4—O—CO—NH—C6H4—COOH, i.e., p-(NN-Di-2-chloroethyloamino)-phenyl- N-(p-carboxyphenyl) - carbamate (later referred to as I.C. 140), has been found to be particularly promising. To check its cytotoxic activity for embryos, and to find out, if possible, whether I.C. 140 has any specific selectivity for particular embryonic tissues, chick and mouse embryos were treated during the early stages of development. Chick embryos were explanted according to the method described by New (1955) at Stage 4 or 5 (Hamburger & Hamilton, 1955), i.e., after a pre-incubation period of 22 hr. As I.C. 140 is difficult to dissolve in water, it was first suspended in an appropriate volume of 0·9 per cent, saline solution. One part of this suspension was then diluted with nine parts of liquid albumen to give the final concentration of 50 or 100 μg. per ml.

Synthesis and anti-tumour activity of 6-methyl derivatives of flavone-8-acetic acid (FAA)

1994 ◽  
Vol 4 (19) ◽  
pp. 2313-2316 ◽  
Author(s):  
R.Alan Aitken ◽  
Michael C. Bibby ◽  
John A. Double ◽  
Roger M. Phillips ◽  
Shiv Kumar Sharma
Keyword(s):  
Acetic Acid ◽  
Anti Tumour Activity ◽  
Methyl Derivatives ◽  
Derivatives Of ◽  
Tumour Activity

Synthesis and Anti – Tumour Activity of Novel Camptothecin – Bile Acid Analogues

2011 ◽  
Vol 8 (8) ◽  
pp. 698-703 ◽  
Author(s):  
Q.-Y. Li ◽  
Y. Gao ◽  
W. Qiu ◽  
Y.-G. Zu ◽  
L. Su ◽  
...  
Keyword(s):  
Bile Acid ◽  
Anti Tumour Activity ◽  
Tumour Activity

scholarly journals Potent anti‐angiogenesis and anti‐tumour activity of pegaptanib‐loaded tetrahedral DNA nanostructure

2019 ◽  
Vol 52 (5) ◽  
Author(s):  
Xueping Xie ◽  
Yuxin Zhang ◽  
Wenjuan Ma ◽  
Xiaoru Shao ◽  
Yuxi Zhan ◽  
...  
Keyword(s):  
Dna Nanostructure ◽  
Anti Tumour Activity ◽  
Tumour Activity

Anti-insulin-like growth factor 1 receptor antibody EM164 (murine AVE1642) exhibits anti-tumour activity alone and in combination with temozolomide against neuroblastoma

2010 ◽  
Vol 46 (18) ◽  
pp. 3251-3262 ◽  
Author(s):  
Birgit Geoerger ◽  
Jean-François Brasme ◽  
Estelle Daudigeos-Dubus ◽  
Paule Opolon ◽  
Corinne Venot ◽  
...  
Keyword(s):  
Growth Factor ◽  
Insulin Like Growth Factor ◽  
Receptor Antibody ◽  
Anti Tumour Activity ◽  
Tumour Activity

New polydentate Ru(III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins

2013 ◽  
Vol 394 ◽  
pp. 616-626 ◽  
Author(s):  
Cristina P. Matos ◽  
Andreia Valente ◽  
Fernanda Marques ◽  
Pedro Adão ◽  
M. Paula Robalo ◽  
...  
Keyword(s):  
Human Serum ◽  
Serum Proteins ◽  
Anti Tumour Activity ◽  
Tumour Activity ◽  
Human Serum Proteins
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