Synthesis and anti-tumour activity of 6-methyl derivatives of flavone-8-acetic acid (FAA)

1994 ◽  
Vol 4 (19) ◽  
pp. 2313-2316 ◽  
Author(s):  
R.Alan Aitken ◽  
Michael C. Bibby ◽  
John A. Double ◽  
Roger M. Phillips ◽  
Shiv Kumar Sharma
Keyword(s):  
Acetic Acid ◽  
Anti Tumour Activity ◽  
Methyl Derivatives ◽  
Derivatives Of ◽  
Tumour Activity

ChemInform Abstract: Synthesis and Antitumor Activity of New Derivatives of Flavone-8- acetic Acid (FAA). Part 1. 6-Methyl Derivatives.

ChemInform ◽  
2010 ◽  
Vol 28 (13) ◽  
pp. no-no
Author(s):  
R. A. AITKEN ◽  
M. C. BIBBY ◽  
J. A. DOUBLE ◽  
R. M. PHILLIPS ◽  
S. K. SHARMA
Keyword(s):  
Acetic Acid ◽  
Antitumor Activity ◽  
Methyl Derivatives ◽  
Derivatives Of

Synthesis and Antitumour Activity of New Derivatives of Flavone-8-acetic Acid (FAA). Part 1: 6-Methyl Derivatives

1996 ◽  
Vol 329 (11) ◽  
pp. 489-497 ◽  
Author(s):  
R. Alan Aitkena ◽  
Michael C. Bibby ◽  
John A. Double ◽  
Roger M. Phillips ◽  
Shiv Kumar Sharma
Keyword(s):  
Acetic Acid ◽  
Antitumour Activity ◽  
Methyl Derivatives ◽  
Derivatives Of

New organotin(IV) derivatives of dipeptides as models for metal-protein interactions:in vitro anti-tumour activity

2003 ◽  
Vol 17 (5) ◽  
pp. 305-314 ◽  
Author(s):  
Mala Nath ◽  
Sandeep Pokharia ◽  
Xueqing Song ◽  
George Eng ◽  
Marcel Gielen ◽  
...  
Keyword(s):  
Anti Tumour Activity ◽  
Derivatives Of ◽  
Tumour Activity

Anti-mesodermal Activity of a Nitrogen Mustard Derivative

Development ◽  
1963 ◽  
Vol 11 (4) ◽  
pp. 689-696
Author(s):  
A. Jurand
Keyword(s):  
Nitrogen Mustard ◽  
Saline Solution ◽  
Embryonic Tissues ◽  
Anti Tumour Activity ◽  
Stage 4 ◽  
Cent Saline ◽  
Specific Selectivity ◽  
Walker Carcinoma ◽  
Derivatives Of ◽  
Tumour Activity

Amongst the numerous derivatives of nitrogen mustard that have been tested for their anti-tumour activity on Walker carcinoma by Danielli and his collaborators (1961), (Cl—CH2—CH2)2: N—C6H4—O—CO—NH—C6H4—COOH, i.e., p-(NN-Di-2-chloroethyloamino)-phenyl- N-(p-carboxyphenyl) - carbamate (later referred to as I.C. 140), has been found to be particularly promising. To check its cytotoxic activity for embryos, and to find out, if possible, whether I.C. 140 has any specific selectivity for particular embryonic tissues, chick and mouse embryos were treated during the early stages of development. Chick embryos were explanted according to the method described by New (1955) at Stage 4 or 5 (Hamburger & Hamilton, 1955), i.e., after a pre-incubation period of 22 hr. As I.C. 140 is difficult to dissolve in water, it was first suspended in an appropriate volume of 0·9 per cent, saline solution. One part of this suspension was then diluted with nine parts of liquid albumen to give the final concentration of 50 or 100 μg. per ml.

ChemInform Abstract: Synthesis and Anti-Tumor Activity of 6-Methyl Derivatives of Flavone-8- acetic Acid (FAA).

ChemInform ◽  
2010 ◽  
Vol 26 (17) ◽  
pp. no-no
Author(s):  
R. A. AITKEN ◽  
M. C. BIBBY ◽  
J. A. DOUBLE ◽  
R. M. PHILLIPS ◽  
S. K. SHARMA
Keyword(s):  
Acetic Acid ◽  
Methyl Derivatives ◽  
Anti Tumor Activity ◽  
Derivatives Of
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