Markovnikov versus anti‐Markovnikov addition and C–H activation: Pd–Cu synergistic catalysis

2020 ◽  
Vol 35 (1) ◽  
Author(s):  
Zakir Ullah ◽  
Renjith Thomas
Keyword(s):  
Synergistic Catalysis ◽  
Markovnikov Addition

Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleo-philes to Allenamides Catalyzed by a Synergistic Copper/Enamine System

2020 ◽  
Author(s):  
Rémi Blieck ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Catalytic System ◽  
Secondary Amine ◽  
Primary Amine ◽  
Synergistic Catalysis ◽  
Enantioselective Addition ◽  
Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

Harnessing Applied Potential: The Anti-Markovnikov Hydrocarboxylation of Substituted Olefins

2019 ◽  
Author(s):  
Anas Alkayal ◽  
Volodymyr Tabas ◽  
Andrei V. Malkov ◽  
Benjamin Buckley
Keyword(s):  
Carboxylic Acid ◽  
Applied Potential ◽  
Markovnikov Addition

<div>The construction of carboxylic acid compounds in a selective fashion, from low value materials such as alkenes remains a long-standing challenge to synthetic chemists. In particular, anti-Markovnikov addition to styrenes are underdeveloped. Herein we report a new electrosynthetic approach to the selective hydrocarboxylation of substituted alkenes.</div>

Harnessing Applied Potential: The Anti-Markovnikov Hydrocarboxylation of Substituted Olefins

2019 ◽  
Author(s):  
Anas Alkayal ◽  
Volodymyr Tabas ◽  
Andrei V. Malkov ◽  
Benjamin Buckley
Keyword(s):  
Carboxylic Acid ◽  
Applied Potential ◽  
Markovnikov Addition

<div>The construction of carboxylic acid compounds in a selective fashion, from low value materials such as alkenes remains a long-standing challenge to synthetic chemists. In particular, anti-Markovnikov addition to styrenes are underdeveloped. Herein we report a new electrosynthetic approach to the selective hydrocarboxylation of substituted alkenes.</div>

ChemInform Abstract: Rhodium-Catalyzed anti-Markovnikov Addition of Triphenylphosphine to 1,3-Dienes - A Novel Method to Separate Pure (Z)-1,3-Alkadienes from Isomeric Mixtures.

ChemInform ◽  
2010 ◽  
Vol 33 (33) ◽  
pp. no-no
Author(s):  
Mieko Arisawa ◽  
Ryohei Momozuka ◽  
Masahiko Yamaguchi
Keyword(s):  
Novel Method ◽  
Markovnikov Addition ◽  
Isomeric Mixtures

High efficiency reduction of CO2 to CO and CH4 via photothermal synergistic catalysis of lead-free perovskite Cs3Sb2I9

2021 ◽  
Vol 294 ◽  
pp. 120236
Author(s):  
Yingying Wang ◽  
Qixin Zhou ◽  
Yongfa Zhu ◽  
Dongsheng Xu
Keyword(s):  
High Efficiency ◽  
Lead Free ◽  
Synergistic Catalysis ◽  
Reduction Of Co2

Diols Activation via Cu/Borinic Acids Synergistic Catalysis in Atroposelective Ring‐Opening of Cyclic Diaryliodoniums

2020 ◽  
Author(s):  
Zhenhua Gu ◽  
Kun Zhao ◽  
Shan Yang ◽  
Qi Gong ◽  
Longhui Duan
Keyword(s):  
Ring Opening ◽  
Synergistic Catalysis

Oxidative and Redox‐Neutral Approaches to Symmetrical Diamines and Diols by Single Electron Transfer/Hydrogen Atom Transfer Synergistic Catalysis

2020 ◽  
Vol 2020 (46) ◽  
pp. 7151-7155 ◽  
Author(s):  
Masashi Fujita ◽  
Fumihisa Kobayashi ◽  
Takafumi Ide ◽  
Hiromichi Egami ◽  
Yoshitaka Hamashima
Keyword(s):  
Electron Transfer ◽  
Hydrogen Atom ◽  
Hydrogen Atom Transfer ◽  
Single Electron ◽  
Atom Transfer ◽  
Single Electron Transfer ◽  
Synergistic Catalysis

Synergistic Catalysis via Brønsted Acid Modulated Frustrated Lewis Pair‐Like Reaction in Carbodicarbene

2021 ◽  
Author(s):  
Tiow-Gan Ong ◽  
Yi-Chen Chan ◽  
Yuna Bai ◽  
Wen-Ching Chen ◽  
Hsing-Yin Chen ◽  
...  
Keyword(s):  
Bronsted Acid ◽  
Brønsted Acid ◽  
Synergistic Catalysis ◽  
Frustrated Lewis Pair ◽  
Brönsted Acid

scholarly journals Site-specific Umpolung amidation of carboxylic acids via triplet synergistic catalysis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yunyun Ning ◽  
Shuaishuai Wang ◽  
Muzi Li ◽  
Jie Han ◽  
Chengjian Zhu ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Functional Group ◽  
Amide Bond ◽  
Coupling Reagents ◽  
Complex Molecules ◽  
Bond Forming ◽  
Synergistic Catalysis ◽  
Wide Range ◽  
Amidation Reaction ◽  
Forming Methods

AbstractDevelopment of catalytic amide bond-forming methods is important because they could potentially address the existing limitations of classical methods using superstoichiometric activating reagents. In this paper, we disclose an Umpolung amidation reaction of carboxylic acids with nitroarenes and nitroalkanes enabled by the triplet synergistic catalysis of FeI2, P(V)/P(III) and photoredox catalysis, which avoids the production of byproducts from stoichiometric coupling reagents. A wide range of carboxylic acids, including aliphatic, aromatic and alkenyl acids participate smoothly in such reactions, generating structurally diverse amides in good yields (86 examples, up to 97% yield). This Umpolung amidation strategy opens a method to address challenging regioselectivity issues between nucleophilic functional groups, and complements the functional group compatibility of the classical amidation protocols. The synthetic robustness of the reaction is demonstrated by late-stage modification of complex molecules and gram-scale applications.

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