Investigation of DNA binding and bioactivities of furan cored Schiff base Cu (II), Ni (II), and Co (III) complexes: Synthesis, characterization and spectroscopic properties

2021 ◽  
Author(s):  
Kadtala Venkateswarlu ◽  
Sreenu Daravath ◽  
Gali Ramesh ◽  
P. V. Anantha Lakshmi ◽  
Shivaraj
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Spectroscopic Properties

scholarly journals DNA binding properties of 2ʹ-hydroxyflavanon and Schiff base derivative

2019 ◽  
Vol 64 (2) ◽  
pp. 222-228
Author(s):  
V. M. Korolevich ◽  
P. Blazinska ◽  
A. Sykula ◽  
E. Lodyga-Chruscinska
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Spectroscopic Properties ◽  
Binding Properties ◽  
Base Modification ◽  
Whole Plant ◽  
Base Derivative ◽  
Anti Inflammatory ◽  
Dna Binding Properties

Flavanoids a class of plant and fungus secondary metabolites. 2ʹ-Hydroxyflavanone was previously isolated from Mimosa pudica (L.) whole plant and was found to exhibit anti-inflammatory effects in vitro and binding with calf timus DNA. There are also reports on anti-inflammatory properties of compounds bearing flavanone/chromone nucleus. The aim of this work was to develop a synthesis of new azomethine compounds derived from flavanones, to examine their spectroscopic properties and interaction with DNA. 2ʹ-Hydroxyflavanone and thiocarbohydrazide were used as substrates in the synthesis. The obtained products were analyzed by 1H NMR spectroscopy, UVVis. Ultraviolet spectroscopy was used to analyze the chemical-physical properties. Mechanism of interaction of bioactive 2ʹ-hydroxyflavanone with calf thymus deoxyribonucleic acid (DNA) was studied employing UV absorption. 2ʹ-Hydroxyflavanon and 2ʹHFTCH are photostable in DMSO. The interaction of 2ʹ-hydroxyflavanone and its derivative occurs by the mechanism of intercalation. The change in the structure of the 2ʹ-hydroxyflavanone molecule by Schiff base modification leads to an increase in DNA-binding properties. High binding ability of 2ʹ-hydroxyflavanone with DNA may be useful for development of new anti-inflammatory and antimicrobial remedies.

Mixed (phthalocyanine)(Schiff-base) terbium(iii)–alkali metal(i)/zinc(ii) complexes: synthesis, structures, and spectroscopic properties

CrystEngComm ◽  
2013 ◽  
Vol 15 (47) ◽  
pp. 10383 ◽  
Author(s):  
Qi Ma ◽  
Xuenan Feng ◽  
Wei Cao ◽  
Hailong Wang ◽  
Jianzhuang Jiang
Keyword(s):  
Schiff Base ◽  
Alkali Metal ◽  
Spectroscopic Properties

Grid-corner analogues: Synthesis, characterisation and spectroscopic properties of meridional complexes of tridentate NNO Schiff-base ligands

Polyhedron ◽  
2010 ◽  
Vol 29 (1) ◽  
pp. 178-187 ◽  
Author(s):  
Artur R. Stefankiewicz ◽  
Monika Wałęsa-Chorab ◽  
Hanna B. Szcześniak ◽  
Violetta Patroniak ◽  
Maciej Kubicki ◽  
...  
Keyword(s):  
Schiff Base ◽  
Spectroscopic Properties ◽  
Schiff Base Ligands

Characteristic and spectroscopic properties of the Schiff-base model compounds

2009 ◽  
Vol 74 (4) ◽  
pp. 949-954 ◽  
Author(s):  
B. Jarząbek ◽  
B. Kaczmarczyk ◽  
D. Sęk
Keyword(s):  
Schiff Base ◽  
Spectroscopic Properties ◽  
Model Compounds

scholarly journals Synthesis, X-ray Structure, Spectroscopic Properties and DFT Studies of a Novel Schiff Base

2014 ◽  
Vol 15 (10) ◽  
pp. 18706-18724 ◽  
Author(s):  
Kew-Yu Chen ◽  
Hsing-Yang Tsai
Keyword(s):  
Schiff Base ◽  
Spectroscopic Properties ◽  
Dft Studies ◽  
X Ray

scholarly journals Synthesis, Spectral Characterization, Docking Analysis, DNA Binding/Cleavage, Antimicrobial and Cytotoxic Activity of New Dimeric Antipyrine-Schiff Base Metal Complexes

2018 ◽  
Vol 31 (1) ◽  
pp. 199-212 ◽  
Author(s):  
Abdel-Nasser M.A. Alaghaz ◽  
Amani S. Alturiqi ◽  
Reda A. Ammar ◽  
Mohamed E. Zayed
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Metal Complexes ◽  
Cytotoxic Activity ◽  
Base Metal ◽  
Spectral Characterization ◽  
Docking Analysis ◽  
Schiff Base Metal Complexes

Synthesis, DNA binding and antibacterial activity of metal(II) complexes of a benzimidazole Schiff base

Polyhedron ◽  
2019 ◽  
Vol 157 ◽  
pp. 326-334 ◽  
Author(s):  
Khalid Mahmood ◽  
Waleed Hashmi ◽  
Hammad Ismail ◽  
Bushra Mirza ◽  
Brendan Twamley ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Dna Binding

Spectra and DNA-binding affinities of Copper(II), Nickel(II) complexes with a novel glycine Schiff base derived from chromone

2007 ◽  
Vol 68 (3) ◽  
pp. 912-917 ◽  
Author(s):  
Dong-dong Qin ◽  
Zheng-yin Yang ◽  
Bao-dui Wang
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Binding Affinities
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