scholarly journals Immunohistochemical Analysis of Nucleotide Excision Repair Factors XPA and XPB in Adult Rat Brain

2008 ◽  
Vol 291 (7) ◽  
pp. 775-780 ◽  
Author(s):  
Shan-Zheng Yang ◽  
Yi-Fan Zhang ◽  
Ling-Mei Zhang ◽  
Ya-Ling Huang ◽  
Feng-Yan Sun
Keyword(s):  
Rat Brain ◽  
Nucleotide Excision Repair ◽  
Excision Repair ◽  
Immunohistochemical Analysis ◽  
Adult Rat ◽  
Nucleotide Excision ◽  
Adult Rat Brain

scholarly journals Pattern of chondroitin sulfate proteoglycan expression after ablation of the sensorimotor cortex of the neonatal and adult rat brain

2008 ◽  
Vol 60 (4) ◽  
pp. 581-591
Author(s):  
Sanja Dacic ◽  
Sanja Pekovic ◽  
Maja Stojiljkovic ◽  
Irena Lavrnja ◽  
Danijela Stojkov ◽  
...  
Keyword(s):  
Chondroitin Sulfate ◽  
Rat Brain ◽  
Sensorimotor Cortex ◽  
Immunohistochemical Analysis ◽  
Recovery Process ◽  
Adult Brain ◽  
Sulfate Proteoglycan ◽  
Adult Rats ◽  
Adult Rat ◽  
Adult Rat Brain

The central nervous system has a limited capacity for self-repair after damage. However, the neonatal brain has agreater capacity for recovery than the adult brain. These differences in the regenerative capability depend on local environmental factors and the maturational stage of growing axons. Among molecules which have both growth-promoting and growth-inhibiting activities is the heterogeneous class of chondroitin sulfate proteoglycans (CSPGs). In this paper, we investigated the chondroitin-4 and chondroitin-6 sulfate proteoglycan expression profile after left sensorimotor cortex ablation of the neonatal and adult rat brain. Immunohistochemical analysis revealed that compared to the normal uninjured cortex, lesion provoked up regulation of CSPGs showing a different pattern of expression in the neonatal vs. the adult brain. Punctuate and membrane-bound labeling was predominate after neonatal lesion, where as heavy deposition of staining in the extracellular matrix was observed after adult lesion. Heavy deposition of CSPG immunoreactivity around the lesionsite in adult rats, in contrast to a less CSPG-rich environment in neonatal rats, indicated that enhancement of the recovery process after neonatal injury is due to amore permissive environment.

scholarly journals Regional distribution of 5α-reductase type 2 in the adult rat brain: An immunohistochemical analysis

2013 ◽  
Vol 38 (2) ◽  
pp. 281-293 ◽  
Author(s):  
M. Paola Castelli ◽  
Alberto Casti ◽  
Angelo Casu ◽  
Roberto Frau ◽  
Marco Bortolato ◽  
...  
Keyword(s):  
Rat Brain ◽  
Regional Distribution ◽  
Immunohistochemical Analysis ◽  
Adult Rat ◽  
Adult Rat Brain

Immunohistochemical analysis of nuclear lamins in the glial cells of adult rat brain

2007 ◽  
Vol 58 ◽  
pp. S209
Author(s):  
Yasuharu Takamori ◽  
Tetsuji Mori ◽  
Taketoshi Wakabayashi ◽  
Hisao Yamada
Keyword(s):  
Rat Brain ◽  
Glial Cells ◽  
Immunohistochemical Analysis ◽  
Adult Rat ◽  
Nuclear Lamins ◽  
Adult Rat Brain

Expression of neurocan after transient middle cerebral artery occlusion in adult rat brain

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S217-S217
Author(s):  
Kentaro Deguchi ◽  
Mikiro Takaishi ◽  
Takeshi Hayashi ◽  
Atsuhiko Oohira ◽  
Shoko Nagotani ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Rat Brain ◽  
Middle Cerebral Artery Occlusion ◽  
Cerebral Artery ◽  
Artery Occlusion ◽  
Adult Rat ◽  
Adult Rat Brain ◽  
Cerebral Artery Occlusion

MITF controls the interface of nucleotide excision repair and transcription through direct regulation of GTF2H1

2015 ◽  
Vol 227 (03) ◽  
Author(s):  
M Seoane ◽  
J Strauss ◽  
AC Puller ◽  
M Noshiravani ◽  
S Feldhaus ◽  
...  
Keyword(s):  
Nucleotide Excision Repair ◽  
Excision Repair ◽  
Nucleotide Excision ◽  
Direct Regulation
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