scholarly journals Synthesis and Biological Evaluation of Pentacycloundecylamines and Triquinylamines as Voltage-Gated Calcium Channel Blockers

2016 ◽  
Vol 349 (4) ◽  
pp. 252-267 ◽  
Author(s):  
Lois-May Young ◽  
Werner J. Geldenhuys ◽  
Olwen C. Domingo ◽  
Sarel F. Malan ◽  
Cornelis J. Van der Schyf
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Biological Evaluation ◽  
Channel Blockers ◽  
Voltage Gated ◽  
Voltage Gated Calcium Channel ◽  
Synthesis And Biological Evaluation

scholarly journals Voltage-gated calcium channel blockers for psychiatric disorders: genomic reappraisal

2019 ◽  
Vol 216 (5) ◽  
pp. 250-253 ◽  
Author(s):  
Paul J. Harrison ◽  
Elizabeth M. Tunbridge ◽  
Annette C. Dolphin ◽  
Jeremy Hall
Keyword(s):  
Calcium Channels ◽  
Calcium Channel ◽  
Psychiatric Disorders ◽  
Calcium Channel Blockers ◽  
Channel Blockers ◽  
Risk Genes ◽  
Voltage Gated ◽  
Voltage Gated Calcium Channels ◽  
Voltage Gated Calcium Channel ◽  
Second Use

SummaryWe reappraise the psychiatric potential of calcium channel blockers (CCBs). First, voltage-gated calcium channels are risk genes for several disorders. Second, use of CCBs is associated with altered psychiatric risks and outcomes. Third, research shows there is an opportunity for brain-selective CCBs, which are better suited to psychiatric indications.

Pre-clinical evaluation of voltage-gated calcium channel blockers derived from the spider P. nigriventer in glioma progression

Toxicon ◽  
2017 ◽  
Vol 129 ◽  
pp. 58-67 ◽  
Author(s):  
Natália Fontana Nicoletti ◽  
Thaís Cristina Erig ◽  
Rafael Fernandes Zanin ◽  
Marcelo Ricardo Roxo ◽  
Nelson Pires Ferreira ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Clinical Evaluation ◽  
Calcium Channel Blockers ◽  
Channel Blockers ◽  
Voltage Gated ◽  
Voltage Gated Calcium Channel ◽  
Glioma Progression

ChemInform Abstract: Facile Synthesis and Biological Evaluation of 3,3-Diphenylpropanoyl Piperazines as T-Type Calcium Channel Blockers.

ChemInform ◽  
2011 ◽  
Vol 42 (20) ◽  
pp. no-no
Author(s):  
Yeon-hee Choi ◽  
Du Jong Baek ◽  
Seon Hee Seo ◽  
Jae Kyun Lee ◽  
Ae Nim Pae ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Biological Evaluation ◽  
Channel Blockers ◽  
Facile Synthesis ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers

1999 ◽  
Vol 9 (8) ◽  
pp. 1121-1126 ◽  
Author(s):  
Lain-Yen Hu ◽  
Todd R. Ryder ◽  
Sham S. Nikam ◽  
Elizabeth Millerman ◽  
Balazs G. Szoke ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Biological Evaluation ◽  
Channel Blockers ◽  
Synthesis And Biological Evaluation

ChemInform Abstract: Synthesis and Biological Evaluation of Substituted 4-(OBz)Phenylalanine Derivatives as Novel N-Type Calcium Channel Blockers.

ChemInform ◽  
2010 ◽  
Vol 30 (33) ◽  
pp. no-no
Author(s):  
Lain-Yen Hu ◽  
Todd R. Ryder ◽  
Sham S. Nikam ◽  
Elizabeth Millerman ◽  
Balazs G. Szoke ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Biological Evaluation ◽  
Channel Blockers ◽  
Synthesis And Biological Evaluation
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