scholarly journals Central bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior cruciate ligament tears and cartilage loss

2007 ◽  
Vol 58 (1) ◽  
pp. 130-136 ◽  
Author(s):  
Gabriela Hernández-Molina ◽  
Ali Guermazi ◽  
Jingbo Niu ◽  
Daniel Gale ◽  
Joyce Goggins ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Anterior Cruciate Ligament ◽  
Knee Osteoarthritis ◽  
Cruciate Ligament ◽  
Cartilage Loss ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee ◽  
Anterior Cruciate ◽  
Cruciate Ligament Tears ◽  
And Cartilage

scholarly journals Radiographic and Symptomatic Knee Osteoarthritis 32 to 37 Years After Acute Anterior Cruciate Ligament Rupture

2020 ◽  
Vol 48 (10) ◽  
pp. 2387-2394 ◽  
Author(s):  
Joanna Kvist ◽  
Stephanie Filbay ◽  
Christer Andersson ◽  
Clare L. Ardern ◽  
Håkan Gauffin
Keyword(s):  
Anterior Cruciate Ligament ◽  
Knee Osteoarthritis ◽  
Knee Replacement ◽  
Cruciate Ligament ◽  
Acl Injury ◽  
Total Sample ◽  
Acl Surgery ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee ◽  
Anterior Cruciate

Background: The long-term prevalence of knee osteoarthritis (OA) after anterior cruciate ligament (ACL) injury is unknown, especially in patients without a history of ACL surgery. Purpose: To (1) describe the prevalence of radiographic OA, symptomatic OA, and knee replacement surgery 32 to 37 years after acute ACL injury and to (2) compare the prevalence of radiographic OA, symptomatic OA, and knee symptoms between patients allocated to early ACL surgery or no ACL surgery and patients who crossed over to ACL surgery. Study Design: Cohort study; Level of evidence, 2. Methods: Participants aged 15 to 40 years at the time of ACL injury were allocated to surgical (augmented or nonaugmented ACL repair) or nonsurgical ACL treatment within 14 days of injury. At 32 to 37 years after the initial injury, 153 participants were followed up with plain weightbearing radiographs and completed 4 subscales from the Knee injury and Osteoarthritis Outcome Score (KOOS). Radiographic OA was defined as Kellgren and Lawrence grade 2 or higher. Symptomatic OA was defined as radiographic OA plus knee symptoms measured with the KOOS. Results: Participants allocated to ACL surgery (n = 64) underwent surgery at a mean ± SD of 5 ± 4 days (range, 0-11 days) after injury. Of the 89 participants allocated to no ACL surgery, 53 remained nonsurgically treated, 27 had ACL surgery within 2 years, and 9 had ACL surgery between 3 and 21 years after injury. In the total sample, 95 participants (62%) had radiographic tibiofemoral OA, including 11 (7%) who had knee replacement. The prevalence of radiographic tibiofemoral OA was lower in the group allocated to ACL surgery compared with the group who never had ACL surgery (50% vs 75%; P = .005). The prevalence of symptomatic OA (50% in the total sample) and patellofemoral radiographic OA (35% in the total sample) was similar between groups. Conclusion: Patients allocated to early ACL surgery, performed a mean 5 days after injury, had a lower prevalence of tibiofemoral radiographic OA at 32 to 37 years after injury compared with patients who never had ACL surgery. The prevalences of symptomatic OA, radiographic patellofemoral OA, and knee symptoms were similar irrespective of ACL treatment. Overall, the prevalence of OA after ACL injury was high. Registration: NCT03182647 (ClinicalTrials.gov identifier)

scholarly journals What’s the rate of knee osteoarthritis 10 years after anterior cruciate ligament injury? An updated systematic review

2019 ◽  
Vol 53 (18) ◽  
pp. 1162-1167 ◽  
Author(s):  
Marthe Mehus Lie ◽  
May Arna Risberg ◽  
Kjersti Storheim ◽  
Lars Engebretsen ◽  
Britt Elin Øiestad
Keyword(s):  
Systematic Review ◽  
Anterior Cruciate Ligament ◽  
Knee Osteoarthritis ◽  
Methodological Quality ◽  
Cruciate Ligament ◽  
Acl Tear ◽  
Knee Oa ◽  
Symptomatic Knee ◽  
Anterior Cruciate

BackgroundThis updated systematic review reports data from 2009 on the prevalence, and risk factors, for knee osteoarthritis (OA) more than 10 years after anterior cruciate ligament (ACL) tear.MethodsWe systematically searched five databases (PubMed, EMBASE, AMED, Cinahl and SPORTDiscus) for prospective and retrospective studies published after 1 August 2008. Studies were included if they investigated participants with ACL tear (isolated or in combination with medial collateral ligament and/or meniscal injuries) and reported symptomatic and/or radiographic OA at a minimum of 10 years postinjury. We used a modified version of the Downs and Black checklist for methodological quality assessment and narrative synthesis to report results. The study protocol was registered in PROSPERO.ResultsForty-one studies were included. Low methodological quality was revealed in over half of the studies. At inclusion, age ranged from 23 to 38 years, and at follow-up from 31 to 51 years. Sample sizes ranged from 18 to 780 participants. The reported radiographic OA prevalence varied between 0% and 100% >10 years after injury, regardless of follow-up time. The studies with low and high methodological quality reported a prevalence of radiographic OA between 0%–100% and 1%–80%, respectively. One study reported symptomatic knee OA for the tibiofemoral (TF) joint (35%), and one study reported symptomatic knee OA for the patellofemoral (PF) joint (15%). Meniscectomy was the only consistent risk factor determined from the data synthesis.ConclusionRadiographic knee OA varied between 0% and 100% in line with our previous systematic review from 2009. Symptomatic and radiographic knee OA was differentiated in two studies only, with a reported symptomatic OA prevalence of 35% for the TF joint and 15% for PF joint. Future cohort studies need to include measurement of symptomatic knee OA in this patient group.PROSPERO registration numberCRD42016042693.

Good results five years after surgical management of anterior cruciate ligament tears, and meniscal and cartilage injuries

2010 ◽  
Vol 18 (10) ◽  
pp. 1385-1390 ◽  
Author(s):  
Leonardo Osti ◽  
Rocco Papalia ◽  
Angelo Del Buono ◽  
Cirino Amato ◽  
Vincenzo Denaro ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Surgical Management ◽  
Cruciate Ligament ◽  
Cartilage Injuries ◽  
Anterior Cruciate ◽  
Cruciate Ligament Tears ◽  
And Cartilage

The Effects of Time Course after Anterior Cruciate Ligament Injury in Correlation with Meniscal and Cartilage Loss

2001 ◽  
Vol 29 (1) ◽  
pp. 9-14 ◽  
Author(s):  
George A. C. Murrell ◽  
Sirish Maddali ◽  
Lois Horovitz ◽  
Stephen P. Oakley ◽  
Russell F. Warren
Keyword(s):  
Anterior Cruciate Ligament ◽  
Anterior Cruciate Ligament Injury ◽  
Time Course ◽  
Cruciate Ligament ◽  
Cartilage Loss ◽  
Ligament Injury ◽  
Anterior Cruciate ◽  
And Cartilage
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