Modeling approach to control of carbohydrate metabolism during citric acid accumulation byAspergillus niger: II. Sensitivity analysis

1994 ◽  
Vol 44 (1) ◽  
pp. 112-118 ◽  
Author(s):  
N�stor V. Torres
Keyword(s):  
Sensitivity Analysis ◽  
Citric Acid ◽  
Carbohydrate Metabolism ◽  
Modeling Approach ◽  
Acid Accumulation ◽  
Citric Acid Accumulation

Regulatory aspects of carbohydrate metabolism in relation to citric acid accumulation by aspergillus niger

1991 ◽  
Vol 11 (6) ◽  
pp. 571-581 ◽  
Author(s):  
F. A. Steinböck ◽  
I. Held ◽  
S. Choojun ◽  
H. Harmsen ◽  
M. Röhr ◽  
...  
Keyword(s):  
Citric Acid ◽  
Aspergillus Niger ◽  
Carbohydrate Metabolism ◽  
Regulatory Aspects ◽  
Acid Accumulation ◽  
Citric Acid Accumulation

CrMYB73 , a PH -like gene, contributes to citric acid accumulation in citrus fruit

2015 ◽  
Vol 197 ◽  
pp. 212-217 ◽  
Author(s):  
Shao-jia Li ◽  
Xiao-juan Liu ◽  
Xiu-lan Xie ◽  
Chong-de Sun ◽  
Donald Grierson ◽  
...  
Keyword(s):  
Citric Acid ◽  
Citrus Fruit ◽  
Acid Accumulation ◽  
Citric Acid Accumulation

A TOXICOLOGICAL AND BIOCHEMICAL STUDY OF ω-FLUORO COMPOUNDS

1957 ◽  
Vol 35 (1) ◽  
pp. 407-417
Author(s):  
J. M. Parker ◽  
I. G. Walker
Keyword(s):  
Respiratory Failure ◽  
Citric Acid ◽  
Biochemical Study ◽  
Toxic Compounds ◽  
Molar Basis ◽  
Acid Accumulation ◽  
Citric Acid Accumulation ◽  
Substituted Urea

A series of ω-fluoro compounds have been examined for their toxicity to mice and their ability to cause accumulation of citric acid in vivo. It was found that the toxic members did cause citric acid accumulation. Since fluoroacetate causes citric acid accumulation, it was concluded that the activity of these compounds and their effect on citric acid levels is in agreement with the hypothesis that these compounds were degraded to a fluoroacetyl derivative. The findings suggested that mice can degrade to fluoroacetate, compounds containing the following terminal radicals: amine, nitro, nitrile, thiocyanate, isothiocyanate, mercaptan, fluoride, chloride, bromide, iodide, tosylate, mesylate, 2-ketone, sulphonyl chloride, 1-alkyne, ether, substituted urea, aldehyde, and carboxyl. When compared on a molar basis several of the toxic compounds containing four or more carbon atoms were more toxic than fluoroacetate. 6-Fluorohexylamiue and 6-fluorohexanoic acid, which were representative of this type of compound, were investigated in this regard. These compounds, like fluoroacetate, were not immediately reactive but appeared to be converted to the toxic end-product more efficiently. In the dog, death from 6-fluorohexylamine was due to respiratory failure.

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