scholarly journals High-throughput combinatorial screening reveals interactions between signaling molecules that regulate adult neural stem cell fate

2018 ◽  
Vol 116 (1) ◽  
pp. 193-205 ◽  
Author(s):  
Riya Muckom ◽  
Sean McFarland ◽  
Chun Yang ◽  
Brian Perea ◽  
Megan Gentes ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
High Throughput ◽  
Signaling Molecules ◽  
Combinatorial Screening ◽  
Adult Neural Stem Cell ◽  
Stem Cell Fate

scholarly journals Brain micro-ecologies: neural stem cell niches in the adult mammalian brain

2007 ◽  
Vol 363 (1489) ◽  
pp. 123-137 ◽  
Author(s):  
Patricio A Riquelme ◽  
Elodie Drapeau ◽  
Fiona Doetsch
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Subventricular Zone ◽  
Hippocampal Formation ◽  
Mammalian Brain ◽  
Adult Neural Stem Cell ◽  
Stem Cell Fate ◽  
Stem Cell Niches ◽  
Adult Mammalian Brain

Neurogenesis persists in two germinal regions in the adult mammalian brain, the subventricular zone of the lateral ventricles and the subgranular zone in the hippocampal formation. Within these two neurogenic niches, specialized astrocytes are neural stem cells, capable of self-renewing and generating neurons and glia. Cues within the niche, from cell–cell interactions to diffusible factors, are spatially and temporally coordinated to regulate proliferation and neurogenesis, ultimately affecting stem cell fate choices. Here, we review the components of adult neural stem cell niches and how they act to regulate neurogenesis in these regions.

scholarly journals Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

2017 ◽  
Vol 6 (11) ◽  
pp. 1551-1561 ◽  
Author(s):  
J.D. Gothié ◽  
A. Sébillot ◽  
C. Luongo ◽  
M. Legendre ◽  
C. Nguyen Van ◽  
...  
Keyword(s):  
Stem Cell ◽  
Thyroid Hormone ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Mitochondrial Metabolism ◽  
Adult Neural Stem Cell ◽  
Stem Cell Fate

Energy metabolism in adult neural stem cell fate

2011 ◽  
Vol 93 (2) ◽  
pp. 182-203 ◽  
Author(s):  
Victoria A. Rafalski ◽  
Anne Brunet
Keyword(s):  
Stem Cell ◽  
Energy Metabolism ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Adult Neural Stem Cell ◽  
Stem Cell Fate

Instructions from the Vascular System - Directing Neural Stem Cell Fate in Health and Disease

2014 ◽  
Vol 21 (19) ◽  
pp. 2190-2207 ◽  
Author(s):  
S. Schildge ◽  
C. Bohrer ◽  
S. Pfurr ◽  
K. Mammadzada ◽  
K. Schachtrup ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Vascular System ◽  
Stem Cell Fate ◽  
Health And Disease

scholarly journals The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation

2012 ◽  
Vol 72 (7) ◽  
pp. 1068-1084 ◽  
Author(s):  
Allison M. Bond ◽  
Oneil G. Bhalala ◽  
John A. Kessler
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Bone Morphogenetic Proteins ◽  
Stem Cell Fate

Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters

EMBO Reports ◽  
2021 ◽  
Author(s):  
Shang‐Kun Dai ◽  
Pei‐Pei Liu ◽  
Hong‐Zhen Du ◽  
Xiao Liu ◽  
Ya‐Jie Xu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Fate ◽  
Neural Stem Cell ◽  
Stem Cell Fate ◽  
Cell Fate Decisions
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