Non‐carbon loss long‐term continuous lactic acid production from mixed sugars using thermophilic Enterococcus faecium QU 50

2020 ◽  
Vol 117 (6) ◽  
pp. 1673-1683 ◽  
Author(s):  
Mohamed Ali Abdel‐Rahman ◽  
Jiaming Tan ◽  
Yukihiro Tashiro ◽  
Takeshi Zendo ◽  
Kenji Sakai ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Enterococcus Faecium ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Carbon Loss ◽  
Mixed Sugars

Enterococcus faecium QU 50: a novel thermophilic lactic acid bacterium for high-yield l-lactic acid production from xylose

2014 ◽  
Vol 362 (2) ◽  
pp. 1-7 ◽  
Author(s):  
Mohamed Ali Abdel-Rahman ◽  
Yukihiro Tashiro ◽  
Takeshi Zendo ◽  
Kenji Sakai ◽  
Kenji Sonomoto
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacterium ◽  
Enterococcus Faecium ◽  
Acid Production ◽  
Lactic Acid Production ◽  
High Yield

scholarly journals Dynamic Simulation of Continuous Mixed Sugars Fermentation with Increasing Cell Retention Time for Lactic Acid Production using Enterococcus mundtii QU 25

2020 ◽  
Author(s):  
Ying Wang ◽  
Ka-Lai Chan ◽  
Mohamed Ali Abdel-Rahman ◽  
Kenji Sonomoto ◽  
Shao-Yuan Leu
Keyword(s):  
Lactic Acid ◽  
Retention Time ◽  
Acid Production ◽  
Fermentation Process ◽  
Lactic Acid Production ◽  
Critical Role ◽  
Cell Retention ◽  
Mixed Sugars ◽  
Enterococcus Mundtii ◽  
Mixed Sugar

Abstract Background: Simultaneous and effective conversion of both pentose and hexoses in fermentation is a critical and challenging task toward the lignocellulosic economy. This study aims to investigate the feasibility of an innovative co-fermentation process featured with cell recycle unit (CF/CR) for mixed sugar utilization. A l-lactic acid producing strain Enterococcus mundtii QU 25 was applied in the continuous fermentation process to utilize the mixed sugar at different productivities over the changes of flowing conditions. Structured numerical platform were constructed with the experiments to optimize the biological process and clarify the cell metabolisms through kinetics analysis. The structured model, kinetic parameters, and achievement of the fermentation strategy shall provide new insights towards whole sugar fermentation via real-time monitoring for process control and optimization.Results: Significant carbon catabolite repression of co-fermentation using glucose/xylose mixture was overcome by replacing glucose with cellobiose, of which the consumption ratio of hexose to pentose was improved dramatically from 10.4:1 to 2.17:1. An outstanding product concentration of 65.15 g·L -1 and productivity of 13.03 g·L -1 ·h -1 were achieved with 50 g·L -1 cellobiose and 30 g·L -1 xylose, at an optimized dilution rate of 0.2 h -1 with gradually increased cell retention time. Among the total lactic acid production, xylose contributed to more than 34% of the mixed sugars, which was close to the related contents in agricultural residuals. The model successfully simulated the transition of sugar consumption, cell growth, and lactic acid production among the batch, continuous process, and CF/CR system.Conclusion: Cell retention time played a critical role in balancing pentose and hexose consumption, cell decay, and lactic acid production in the CF/CR process. With the increase of cell concentration, consumption of mixed sugars increased with the productivity of final products, hence the impacts of substrate inhibiting reduced. With the validated parameters, the model showed highest accuracy simulating the CF/CR process, of which significantly longer cell retention times over hydraulic retention time were tested.

scholarly journals Enantioselective lactic acid production by an Enterococcus faecium strain showing potential in agro-industrial waste bioconversion: Physiological and proteomic studies

2014 ◽  
Vol 173 ◽  
pp. 31-40 ◽  
Author(s):  
Alessandro Pessione ◽  
Michele Zapponi ◽  
Giorgia Mandili ◽  
Paolo Fattori ◽  
Erika Mangiapane ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Enterococcus Faecium ◽  
Acid Production ◽  
Industrial Waste ◽  
Lactic Acid Production ◽  
Faecium Strain

Utilizing Gelatinized Starchy Waste from Rice Noodle Factory as Substrate for L(+)-Lactic Acid Production by Amylolytic Lactic Acid Bacterium Enterococcus faecium K-1

2020 ◽  
Vol 192 (2) ◽  
pp. 353-366 ◽  
Author(s):  
Kridsada Unban ◽  
Ramita Khanongnuch ◽  
Apinun Kanpiengjai ◽  
Kalidas Shetty ◽  
Chartchai Khanongnuch
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacterium ◽  
Enterococcus Faecium ◽  
Acid Production ◽  
Lactic Acid Production

Effective (+)-Lactic Acid Production by Co-fermentation of Mixed Sugars

2010 ◽  
Vol 150 ◽  
pp. 347-348 ◽  
Author(s):  
M.A. Abdel-Rahman ◽  
Y. Tashiro ◽  
T. Zendo ◽  
K. Sonomoto
Keyword(s):  
Lactic Acid ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Mixed Sugars

Amylolytic Enzymes Acquired from L-Lactic Acid Producing Enterococcus faecium K-1 and Improvement of Direct Lactic Acid Production from Cassava Starch

2017 ◽  
Vol 183 (1) ◽  
pp. 155-170 ◽  
Author(s):  
Kridsada Unban ◽  
Apinun Kanpiengjai ◽  
Goro Takata ◽  
Keiko Uechi ◽  
Wen-Chien Lee ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Enterococcus Faecium ◽  
Acid Production ◽  
Lactic Acid Production ◽  
Cassava Starch ◽  
Amylolytic Enzymes

l-Lactic acid production from glycerol coupled with acetic acid metabolism by Enterococcus faecalis without carbon loss

2016 ◽  
Vol 121 (1) ◽  
pp. 89-95 ◽  
Author(s):  
Nao Murakami ◽  
Mana Oba ◽  
Mariko Iwamoto ◽  
Yukihiro Tashiro ◽  
Takuya Noguchi ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Lactic Acid ◽  
Enterococcus Faecalis ◽  
Acid Production ◽  
Acid Metabolism ◽  
Lactic Acid Production ◽  
Carbon Loss

scholarly journals Thermophilic Enterococcus faecium QU 50 enabled open repeated batch fermentation for l-lactic acid production from mixed sugars without carbon catabolite repression

RSC Advances ◽  
2017 ◽  
Vol 7 (39) ◽  
pp. 24233-24241 ◽  
Author(s):  
J. Tan ◽  
M. A. Abdel-Rahman ◽  
M. Numaguchi ◽  
Y. Tashiro ◽  
T. Zendo ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Enterococcus Faecium ◽  
Catabolite Repression ◽  
Acid Production ◽  
Batch Fermentation ◽  
Carbon Catabolite Repression ◽  
Lactic Acid Production ◽  
Acid Fermentation ◽  
Repeated Batch Fermentation ◽  
Repeated Batch

Thermophilic lactic acid bacterium enabled homo-l-lactic acid fermentation from hexose/pentose without carbon catabolite repression, and open repeated production by immobilization.

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