scholarly journals Metabolic Analysis of the Asparagine and Glutamine Dynamics in an Industrial CHO Fed‐Batch Process

2021 ◽  
Author(s):  
Brian James Kirsch ◽  
Sandra V. Bennun ◽  
Adam Mendez ◽  
Amy S. Johnson ◽  
Hongxia Wang ◽  
...  
Keyword(s):  
Batch Process ◽  
Fed Batch ◽  
Metabolic Analysis

Production of Rhamnolipid Biosurfactant from Fed Batch Culture by Pseudomonas aeruginosa using Multiple Substrates

2020 ◽  
Vol 16 (6) ◽  
pp. 928-933
Author(s):  
Jujjavarapu S. Eswari
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Batch Process ◽  
Time Interval ◽  
Fed Batch ◽  
Multiple Substrates ◽  
Surface Active Agents ◽  
Limiting Nutrients ◽  
Limiting Nutrient ◽  
Surface Active ◽  
Rhamnolipid Biosurfactant

Objective: Biosurfactants are the surface active agents which are used for the reduction of surface and interfacial tensions of liquids. Rhamnolipids are the surfactants produced by Pseudomonas aeruginosa. It requires minimum nutrition for its growth as it can also grow in distilled water. The rhamnolipids produced by Pseudomonas aeruginosa are extra-cellular glycolipids consisting of L-rhamnose and 3-hydroxyalkanoic acid. Methods: The fed-batch method for the rhamnolipid production is considered in this study to know the influence of the carbon, nitrogen, phosphorous substrates as growth-limiting nutrients. Pulse feeding is employed for limiting nutrient addition at particular time interval to obtain maximum rhamnolipid formation from Pseudomonas aeruginosa compared with the batch process. Results: Out of 3 fed batch strategies constant glucose fed batch strategy shows best and gave maximum rhamnolipid concentration of 0.134 g/l.

scholarly journals Establishing a Fed‐Batch Process for Protease Expression with Bacillus licheniformis in Polymer‐Based Controlled‐Release Microtiter Plates

2019 ◽  
Vol 15 (2) ◽  
pp. 1900088 ◽  
Author(s):  
Tobias Habicher ◽  
Edward K. A. Rauls ◽  
Franziska Egidi ◽  
Timm Keil ◽  
Tobias Klein ◽  
...  
Keyword(s):  
Controlled Release ◽  
Bacillus Licheniformis ◽  
Batch Process ◽  
Fed Batch ◽  
Microtiter Plates ◽  
Protease Expression

The impact of pH inhomogeneities on CHO cell physiology and fed-batch process performance - two-compartment scale-down modelling and intracellular pH excursion

2017 ◽  
Vol 12 (7) ◽  
pp. 1600633 ◽  
Author(s):  
Matthias Brunner ◽  
Philipp Braun ◽  
Philipp Doppler ◽  
Christoph Posch ◽  
Dirk Behrens ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Batch Process ◽  
Cell Physiology ◽  
Process Performance ◽  
Fed Batch ◽  
Cho Cell ◽  
Scale Down ◽  
The Impact

Estimation of Bioreactor Efficiency Through Structured Hydrodynamic Modeling Case Study of a Pichia pastoris Fed-Batch Process

2005 ◽  
pp. 653-671 ◽  
Author(s):  
Frank Delvigne ◽  
Thami El Mejdoub ◽  
Jacqueline Destain ◽  
Jean-Marc Delroisse ◽  
Micheline Vandenbol ◽  
...  
Keyword(s):  
Pichia Pastoris ◽  
Batch Process ◽  
Hydrodynamic Modeling ◽  
Fed Batch

scholarly journals Biomass soft sensor for a Pichia pastoris fed‐batch process based on phase detection and hybrid modeling

2020 ◽  
Vol 117 (9) ◽  
pp. 2749-2759
Author(s):  
Vincent Brunner ◽  
Manuel Siegl ◽  
Dominik Geier ◽  
Thomas Becker
Keyword(s):  
Pichia Pastoris ◽  
Batch Process ◽  
Soft Sensor ◽  
Hybrid Modeling ◽  
Phase Detection ◽  
Fed Batch

scholarly journals Feeding strategy optimization in interaction with target seeding density of a fed-batch process for monoclonal antibody production

2013 ◽  
Vol 7 (S6) ◽  
Author(s):  
Marie-Françoise Clincke ◽  
Grégory Mathy ◽  
Laura Gimenez ◽  
Guillaume Le Révérend ◽  
Boris Fessler ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Antibody Production ◽  
Feeding Strategy ◽  
Batch Process ◽  
Seeding Density ◽  
Fed Batch ◽  
Monoclonal Antibody Production
Sign in / Sign up

Export Citation Format

Share Document