Antibiotic concentration in the exudate of venous ulcers: The prediction of ulcer healing rate

1983 ◽  
Vol 70 (9) ◽  
pp. 532-534 ◽  
Author(s):  
N. F. Gowland Hopkins ◽  
C. W. Jamieson
Keyword(s):  
Ulcer Healing ◽  
Healing Rate ◽  
Antibiotic Concentration ◽  
Venous Ulcers ◽  
Ulcer Healing Rate

Ankle Motility is a Risk Factor for Healing of Chronic Venous Leg Ulcers

2001 ◽  
Vol 16 (1) ◽  
pp. 38-40 ◽  
Author(s):  
J. R. Barwell ◽  
M. Taylor ◽  
J. Deacon ◽  
C. Davies ◽  
M. R. Whyman ◽  
...  
Keyword(s):  
Risk Factor ◽  
Pump Power ◽  
Ulcer Healing ◽  
Independent Risk Factor ◽  
Healing Rate ◽  
Leg Ulcer ◽  
Venous Leg Ulcer ◽  
Compression Bandaging ◽  
Venous Ulcers ◽  
Ulcer Healing Rate

Objective: To investigate the effect of ankle motility on chronic venous leg ulcer healing, and to relate this to calf pump function and muscle bulk. Methods: This was a prospective cohort study undertaken in a leg ulcer clinic. Ankle motility, calf-ankle circumference ratio and calf pump power (derived from digital photoplethysmography) were assessed as to their effect on ulcer healing rate. Thirty consecutive patients undergoing multi-layer compression bandaging for open chronic venous ulcers were included. Results: Ankle motility was an independent risk factor for ulcer healing ( p = 0.001, hazard ratio 1.08, 95% CI 1.03–1.13). Ankle motility correlated with calf-ankle circumference ratio ( r = 0.48, p<0.01). No relationship was found between photoplethysmography-derived calf pump power, ankle motility or ulcer healing rate. Conclusions Ulcers in legs with poor ankle motility are slower to heal and this may be related to reduced calf muscle bulk. Ankle exercises or physiotherapy could be considered in such patients.

Compression in leg ulcer treatment: inelastic compression

2014 ◽  
Vol 29 (1_suppl) ◽  
pp. 146-152 ◽  
Author(s):  
Giovanni Mosti
Keyword(s):  
Ulcer Healing ◽  
Healing Rate ◽  
Great Majority ◽  
Compression Therapy ◽  
Venous Hypertension ◽  
Reduced Pressure ◽  
Elastic Compression ◽  
Venous Ulcers ◽  
Arterial Inflow ◽  
Pumping Function

Compression therapy is extremely effective in promoting ulcer healing. Which material to use, if elastic or inelastic, is still a matter of debate. This paper will provide an overview on the recent findings in compression therapy mainly for venous or mixed ulcers which are the great majority of leg ulcers. In this paper it will be demonstrated that inelastic compression has been proved to be significantly more effective than elastic compression in reducing venous reflux, increasing venous pumping function and decreasing ambulatory venous hypertension. In addition it is comfortable, well accepted by patients and achieved an extremely high healing rate in venous ulcers. With reduced pressure inelastic compression is able to improve venous pumping function in patients with mixed ulcers without affecting but improving the arterial inflow. It will be also clearly shown that studies claiming a better effect of elastic compression compared to inelastic in favouring healing rate have significant methodological flaws making their conclusions at least doubtful. In conclusion inelastic- is significantly more effective than elastic compression in reducing ambulatory venous hypertension which is the main pathophysiological determinant of venous ulcers and demonstrated to be very effective in getting ulcer healing. New multicentric, randomized and controlled studies, without methodological flaws, will be necessary to prove that elastic- is at least as effective as inelastic compression or, maybe, more effective.

scholarly journals Effect of Laser Irradiation at Different Wavelengths (940, 808, and 658 nm) on Pressure Ulcer Healing: Results from a Clinical Study

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
J. Taradaj ◽  
T. Halski ◽  
M. Kucharzewski ◽  
T. Urbanek ◽  
U. Halska ◽  
...  
Keyword(s):  
Laser Therapy ◽  
Ulcer Healing ◽  
Healing Rate ◽  
Pressure Ulcers ◽  
Maximum Output Power ◽  
Maximum Output ◽  
Average Dose ◽  
Radiation Emission ◽  
Group I ◽  
Ulcer Healing Rate

The aim of the study was to assess the efficacy of laser therapy (at different wavelengths: 940, 808, and 658 nm) for treating pressure ulcers. The primary endpoint in this trial included both the percentage reduction of the ulcer surface area and the percentage of completely healed wounds after one month of therapy (ulcer healing rate). The secondary endpoint was the ulcer healing rate at the follow-up evaluation (3 months after the end of the study). In total, 72 patients with stage II and III pressure ulcers received laser therapy once daily, 5 times per week for 1 month using a (GaAlAs) diode laser with a maximum output power of 50 mW and continuous radiation emission. Three separate wavelengths were used for the laser treatment: 940 nm (group I), 808 nm (group II), and 658 nm (group III). An average dose of 4 J/cm2was applied. In group IV, a placebo was applied (laser device was turned off). The laser therapy at a wavelength of 658 nm appeared to be effective at healing pressure ulcers. The wavelengths of 808 and 940 nm did not have any effect in our study.

EFFECT OF SUPPORT SURFACE ON PRESSURE ULCER HEALING RATE*

2004 ◽  
Vol 31 (Supplement) ◽  
pp. S2
Author(s):  
Rachel Ochs ◽  
Susan Horn ◽  
Randall Smout ◽  
Lia van Rijswijk
Keyword(s):  
Pressure Ulcer ◽  
Ulcer Healing ◽  
Healing Rate ◽  
Support Surface ◽  
Ulcer Healing Rate ◽  
Effect Of Support

EMR-Induced Ulcer Healing Rate According to the Duration of Omeprazole Therapy

2004 ◽  
Vol 59 (5) ◽  
pp. P153
Author(s):  
Sun-Young Lee ◽  
Jae J. Kim ◽  
Jun Haeng Lee ◽  
Young-Ho Kim ◽  
Poong-Lyul Rhee ◽  
...  
Keyword(s):  
Ulcer Healing ◽  
Healing Rate ◽  
Ulcer Healing Rate

scholarly journals Recurrence of Acute Duodenal Ulcer

1994 ◽  
Vol 8 (1) ◽  
pp. 21-26
Author(s):  
RJ Bailey ◽  
IG Morrison-Cleator ◽  
A Farley ◽  
A Archambault ◽  
M Oravec ◽  
...  
Keyword(s):  
Ulcer Healing ◽  
Healing Rate ◽  
Multicentre Trial ◽  
Epigastric Pain ◽  
Symptomatic Relief ◽  
Ulcer Recurrence ◽  
Double Blind ◽  
Duodenal Ulcers ◽  
Treatment Groups ◽  
Ulcer Healing Rate

Nizatidine, 300 mg once nightly, was compared with cimetidine, 800 mg once nightly, for treatment of 212 adult out-patients with acute duodenal ulcers in an eight-week randomized, double-blind, multicentre trial. Patients were endoscoped at weeks 2, 4 and 8, regardless of ulcer healing status. No significant differences in ulcer healing rates between treatment groups were seen at weeks 2 and 4, but at week 8, nizatidine had a significantly higher ulcer healing rate (P=0.036) than cimetidine (86% versus 74%, respectively). Patients with healed ulcers at either week 2 or week 4 had a final endoscopy performed at week 8. The rate of ulcer recurrence was significantly greater (P=0.021) in the cimetidine group at week 8 compared with the nizatidine group: 21% versus 7.3%, respectively. Increasing tolerance to H2receptor antagonist therapy with prolonged use may explain the higher recurrence rate of cimetidine. Both drugs provided equally rapid and effective symptomatic relief from epigastric pain after two weeks of therapy. Both were equally safe and free from treatment-related adverse effects.

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