scholarly journals Systematic review and meta-analysis of additional technologies to enhance angioplasty for infrainguinal peripheral arterial occlusive disease

2013 ◽  
Vol 100 (9) ◽  
pp. 1128-1137 ◽  
Author(s):  
E. L. Simpson ◽  
J. A. Michaels ◽  
S. M. Thomas ◽  
A. J. Cantrell
Keyword(s):  
Systematic Review ◽  
Peripheral Arterial Occlusive Disease ◽  
Meta Analysis ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Peripheral Arterial

scholarly journals Subintimal Angioplasty for Peripheral Arterial Occlusive Disease: A Systematic Review

2008 ◽  
Vol 31 (4) ◽  
pp. 687-697 ◽  
Author(s):  
Rosemarie Met ◽  
Krijn P. Van Lienden ◽  
Mark J. W. Koelemay ◽  
Shandra Bipat ◽  
Dink A. Legemate ◽  
...  
Keyword(s):  
Systematic Review ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Subintimal Angioplasty ◽  
Peripheral Arterial

Meta-analysis of randomised controlled prostaglandin E1 studies in peripheral arterial occlusive disease stages III and IV

VASA ◽  
2004 ◽  
Vol 33 (3) ◽  
pp. 137-144 ◽  
Author(s):  
Creutzig ◽  
Lehmacher ◽  
Elze
Keyword(s):  
Ulcer Healing ◽  
Peripheral Arterial Occlusive Disease ◽  
Response Rate ◽  
Meta Analysis ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Disease Stage ◽  
Treatment Groups ◽  
Peripheral Arterial

Background: The relevance of Prostaglandin E1 (PGE1) in the treatment of peripheral arterial occlusive disease stage III and IV was to be evaluated for the first time by a meta-analysis. Patients and methods: Altogether, 643 patients were analyzed from seven randomized, controlled PGE1 studies that were comparable with regard to patient selection, study design and endpoints. Of these, only placebo-controlled studies (n = 254) were included in the formal meta-analysis using the method of DerSimonian and Laird. Additionally, the response rate and the rate of adverse events were determined for the pooled groups of all studies. Results: At the end of treatment, PGE1 showed a significantly better response (ulcer healing and/or pain reduction) as compared to placebo (47.8% for PGE1 vs. 25.2% for placebo, p = 0.0294). A significant difference in favor of PGE1 was also seen for the combined endpoint “major amputation or death” after 6-month follow-up (22.6% for PGE1 vs. 36.2% for placebo, p = 0.0150). The response rate (ulcer healing and/or pain relief) of the pooled treatment groups was 60.2% for PGE1, 25.2% for placebo, and 53.6% for iloprost. The adverse events rate of the pooled treatment groups showed good tolerability for PGE1 with a rate of 39.6% in comparison to 73.9% for iloprost and 15.4% for placebo. Conclusion: For patients with peripheral arterial occlusive disease stage III or IV not eligible for arterial reconstruction, PGE1 therapy not only has significant beneficial effects over placebo on ulcer healing and pain relief, but also increases the rate of patients surviving with both legs after 6-months follow-up.

scholarly journals Factors influencing quality of life following lower limb amputation for peripheral arterial occlusive disease: A systematic review of the literature

2017 ◽  
Vol 41 (6) ◽  
pp. 537-547 ◽  
Author(s):  
Fiona Davie-Smith ◽  
Elaine Coulter ◽  
Brian Kennon ◽  
Sally Wyke ◽  
Lorna Paul
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Lower Limb ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Lower Limb Amputation ◽  
Limb Amputation ◽  
Peripheral Arterial

Background: The majority of lower limb amputations are undertaken in people with peripheral arterial occlusive disease, and approximately 50% have diabetes. Quality of life is an important outcome in lower limb amputations; little is known about what influences it, and therefore how to improve it. Objectives: The aim of this systematic review was to identify the factors that influence quality of life after lower limb amputation for peripheral arterial occlusive disease. Methods: MEDLINE, EMBASE, CINAHL, PsycINFO, Web of Science and Cochrane databases were searched to identify articles that quantitatively measured quality of life in those with a lower limb amputation for peripheral arterial occlusive disease. Articles were quality assessed by two assessors, evidence tables summarised each article and a narrative synthesis was performed. Study design: Systematic review. Results: Twelve articles were included. Study designs and outcome measures used varied. Quality assessment scores ranged from 36% to 92%. The ability to walk successfully with a prosthesis had the greatest positive impact on quality of life. A trans-femoral amputation was negatively associated with quality of life due to increased difficulty in walking with a prosthesis. Other factors such as older age, being male, longer time since amputation, level of social support and presence of diabetes also negatively affected quality of life. Conclusion: Being able to walk with a prosthesis is of primary importance to improve quality of life for people with lower limb amputation due to peripheral arterial occlusive disease. To further understand and improve the quality of life of this population, there is a need for more prospective longitudinal studies, with a standardised outcome measure. Clinical relevance This is of clinical relevance to those who are involved in the rehabilitation of persons with lower limb amputations. Improved quality of life is associated with successful prosthetic use and focus should be directed toward achieving this.

scholarly journals Quality Indicators in Peripheral Arterial Occlusive Disease Treatment: A Systematic Review

2019 ◽  
Vol 58 (5) ◽  
pp. 738-745 ◽  
Author(s):  
Sandra Hischke ◽  
Henrik C. Rieß ◽  
Maria K. Bublitz ◽  
Levente Kriston ◽  
Thea Schwaneberg ◽  
...  
Keyword(s):  
Systematic Review ◽  
Quality Indicators ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Disease Treatment ◽  
Peripheral Arterial

scholarly journals The Association of Periodontitis and Peripheral Arterial Occlusive Disease—A Systematic Review

2019 ◽  
Vol 20 (12) ◽  
pp. 2936 ◽  
Author(s):  
Mark Kaschwich ◽  
Christian-Alexander Behrendt ◽  
Guido Heydecke ◽  
Andreas Bayer ◽  
Eike Sebastian Debus ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Peripheral Arterial Occlusive Disease ◽  
Case Series ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Pubmed Database ◽  
Peripheral Arterial ◽  
Meta Analyses ◽  
Degrees Of Severity

Background: Observational studies support an association between periodontitis (PD) and atherosclerotic vascular disease, but little is known specifically about peripheral arterial occlusive disease (PAOD). Objectives: To systematically review the evidence for an association between PD and PAOD. Data Sources: Medline via PubMed. Review Methods: We searched the Pubmed database for original studies, case reports, case series, meta-analyses and systematic reviews that assessed whether there is an association between PD (all degrees of severity) and PAOD (all degrees of severity). The reporting of this systematic review was in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement following the Population, Intervention, Control, and Outcome (PICO) format. Results: 17 out of 755 detected studies were included in the qualitative synthesis. Nine studies demonstrated associations between PD and PAOD, and two studies reported associations between tooth loss and PAOD. Six studies addressed the pathomechanism regarding PD as a possible trigger for PAOD. No study that dismissed an association could be detected. Odds ratios or hazard ratios ranged from 1.3 to 3.9 in four large cohort studies after adjusting for established cardiovascular risk factors. Conclusions: The presented evidence supports a link between PD and PAOD. Further studies which address the temporality of PD and PAOD and randomized controlled intervention trials examining the causal impact of PD on PAOD are needed. Although our results cannot confirm a causal role of PD in the development of PAOD, it is likely that PD is associated with PAOD and plays a contributing role.

High prevalence of peripheral arterial occlusive disease (PAOD) in patients with obstructive sleep apnea

Pneumologie ◽  
2012 ◽  
Vol 66 (S 01) ◽  
Author(s):  
G Vogel ◽  
C Schäfer ◽  
L Adam ◽  
J Weisser-Thomas ◽  
C Hammerstingl ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Peripheral Arterial Occlusive Disease ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Obstructive Sleep ◽  
High Prevalence ◽  
Peripheral Arterial
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