Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins

Xiaotian Zhong; Weijun Ma; Caryl L. Meade; Amy S. Tam; Eliza Llewellyn; Richard Cornell; Kaffa Cote; John J. Scarcelli; Jeffrey K. Marshall; Boriana Tzvetkova; Bruno Figueroa; Dana DiNino; Annette Sievers; Christopher Lee; Jane Guo; Evan Mahan; Christopher Francis; Khetemenee Lam; Aaron M. D'Antona; Richard Zollner; Hongli L. Zhu; Ron Kriz; Will Somers; Laura Lin

doi:10.1002/btpr.2724

Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins

Biotechnology Progress ◽

10.1002/btpr.2724 ◽

2018 ◽

Vol 35 (1) ◽

pp. e2724 ◽

Cited By ~ 11

Author(s):

Xiaotian Zhong ◽

Weijun Ma ◽

Caryl L. Meade ◽

Amy S. Tam ◽

Eliza Llewellyn ◽

...

Keyword(s):

Antibody Production ◽

Expression Platform ◽

Therapeutic Glycoproteins

Decision letter for "High‐throughput compound screen reveals mTOR inhibitors as potential therapeutics to reduce (auto)antibody production by human plasma cells"

10.1002/eji.201948241/v2/decision1 ◽

2019 ◽

Keyword(s):

Human Plasma ◽

High Throughput ◽

Antibody Production ◽

Plasma Cells ◽

Mtor Inhibitors ◽

Auto Antibody ◽

Potential Therapeutics

Genetic Control of DH Reading Frame and Its Effect on B-Cell Development and Antigen-Specifc Antibody Production

Critical Reviews™ in Immunology ◽

10.1615/critrevimmunol.v30.i4.20 ◽

2010 ◽

Vol 30 (4) ◽

pp. 327-344 ◽

Cited By ~ 33

Author(s):

Harry W. Schroeder, Jr. ◽

Michael Zemlin ◽

Mohamed Khass ◽

Huan H. Nguyen ◽

Robert L. Schelonka

Keyword(s):

B Cell ◽

Genetic Control ◽

Antibody Production ◽

Cell Development ◽

B Cell Development ◽

Reading Frame

Effects of Dietary Threonine Level on Antibody Production in Growing Broilers

Nihon Chikusan Gakkaiho ◽

10.2508/chikusan.65.956 ◽

1994 ◽

Vol 65 (10) ◽

pp. 956-960 ◽

Cited By ~ 3

Author(s):

Kazuaki TAKAHASHI ◽

Shigeru KONASHI ◽

Yukio AKIBA ◽

Masaaki HORIGUCHI

Keyword(s):

Antibody Production

Detailed Review of Monoclonal Antibody Production and Its Advantage as a Role in Malignancy and Transplant Rejection

International Journal of Scientific and Research Publications (IJSRP) ◽

10.29322/ijsrp.8.11.2018.p8337 ◽

2018 ◽

Vol 8 (11) ◽

Author(s):

Chandrasekaran M M. ◽

N. Sivakumaran

Keyword(s):

Monoclonal Antibody ◽

Antibody Production ◽

Transplant Rejection ◽

Monoclonal Antibody Production ◽

Detailed Review

Lymphocytotoxic antibody production following calf aortic valve xenografts in human cardiac valve replacement

Pathology ◽

10.3109/00313027209068945 ◽

1972 ◽

Vol 4 (3) ◽

pp. 231-234 ◽

Cited By ~ 1

Author(s):

B.J. Stephens ◽

T.J.A. Livsey ◽

M.F. O'Brien

Keyword(s):

Aortic Valve ◽

Valve Replacement ◽

Antibody Production ◽

Cardiac Valve ◽

Cardiac Valve Replacement ◽

Lymphocytotoxic Antibody

Faculty Opinions recommendation of CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1003948.24358 ◽

2002 ◽

Author(s):

John Kearney

Keyword(s):

Antibody Production ◽

Body Cavity ◽

Natural Antibody ◽

Cell Homing

Faculty Opinions recommendation of CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1003948.124307 ◽

2002 ◽

Author(s):

Hugh McDevitt

Keyword(s):

Antibody Production ◽

Body Cavity ◽

Natural Antibody ◽

Cell Homing

Faculty Opinions recommendation of Age- and infection intensity-dependent cytokine and antibody production in human trichuriasis: the importance of IgE.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004706.51067 ◽

2002 ◽

Author(s):

William Evan Secor

Keyword(s):

Antibody Production ◽

Infection Intensity

Faculty Opinions recommendation of Cutting edge: cooperation of IPS-1- and TRIF-dependent pathways in poly IC-enhanced antibody production and cytotoxic T cell responses.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1098907.555070 ◽

2008 ◽

Author(s):

Michael Gale

Keyword(s):

T Cell ◽

Antibody Production ◽

T Cell Responses ◽

Cutting Edge ◽

Cytotoxic T Cell ◽

Cell Responses ◽

Cytotoxic T Cell Responses

Faculty Opinions recommendation of Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718285403.793526433 ◽

2016 ◽

Author(s):

Paul Kubes ◽

Justin Deniset

Keyword(s):

B Cells ◽

Antibody Production ◽

Marginal Zone ◽

Innate Lymphoid Cells ◽

Lymphoid Cells ◽

Marginal Zone B Cells