scholarly journals CD 47 is an adverse prognostic factor and a therapeutic target in gastric cancer

2015 ◽  
Vol 4 (9) ◽  
pp. 1322-1333 ◽  
Author(s):  
Kazumichi Yoshida ◽  
Hironori Tsujimoto ◽  
Kouji Matsumura ◽  
Manabu Kinoshita ◽  
Risa Takahata ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factor ◽  
Therapeutic Target ◽  
Adverse Prognostic Factor

scholarly journals ARL4C might serve as a prognostic factor and a novel therapeutic target for gastric cancer: bioinformatics analyses and biological experiments

2021 ◽  
Vol 25 (8) ◽  
pp. 4014-4027
Author(s):  
Ning Xie ◽  
Yunfan Bai ◽  
Lu Qiao ◽  
Yuru Bai ◽  
Jian Wu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factor ◽  
Therapeutic Target ◽  
Bioinformatics Analyses ◽  
Novel Therapeutic ◽  
Cancer Bioinformatics

scholarly journals KRAS G12V Mutation is an Adverse Prognostic Factor of Chinese Gastric Cancer Patients

2019 ◽  
Vol 10 (4) ◽  
pp. 821-828 ◽  
Author(s):  
Xin-Hui Fu ◽  
Zhi-Ting Chen ◽  
Wen-Hui Wang ◽  
Xin-Juan Fan ◽  
Yan Huang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factor ◽  
Cancer Patients ◽  
Adverse Prognostic Factor ◽  
Gastric Cancer Patients

scholarly journals Hypoxia Promotes Metastasis of Gastric Cancer Through ANXA1 Pathway

2021 ◽  
Author(s):  
Qing-Hua Liu ◽  
Lei Xia ◽  
Xiao-Yue Wu ◽  
Chen-Chen Lu ◽  
Jing-Yuan Song ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cell Migration ◽  
Prognostic Factor ◽  
Therapeutic Target ◽  
Prognostic Markers ◽  
Migration And Invasion ◽  
Annexin A1 ◽  
Node Metastasis ◽  
Hif Pathway

Abstract Background: To determinethe involvement of hypoxia inducible factor1α (HIF) pathway inmetastasis of gastric cancer (GC). Method: It was determined that the expression of HIF and annexin A1 (ANXA1) in human GC (n=76),using immunohis to chemistry, as well as,the involvement of HIF pathway in GC cell migration and invasion in vitro. The correlation between HIF/ANXA1 and the prognosis wasalso evaluated.Results: HIF1αwas substantiallyupregulatedin GC tissues, compared to that of non-cancer. HIF1α was positively correlated withlymph node metastasis, but inversely correlated with survival in GC patients. HIF1αwas an independent prognostic factor in GC patients, and the combination of HIF1α and ANXA1 might serve asuseful prognostic markers in GCpatients.Furthermore,HIF-1αseems topromote GC migration and invasion through HIF1α/ANXA1/MMP-2 pathway. Conclusions: Our findings suggestthat HIF-1αmay serve as a promising prognostic biomarkerand therapeutic target for inhibiting GC metastasis.

scholarly journals HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target

2008 ◽  
Vol 19 (9) ◽  
pp. 1523-1529 ◽  
Author(s):  
C. Gravalos ◽  
A. Jimeno
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factor ◽  
Therapeutic Target ◽  
Novel Therapeutic

scholarly journals COL12A1, a novel potential prognostic factor and therapeutic target in gastric cancer

2019 ◽  
Author(s):  
Xiaoxia Jiang ◽  
Mengjie Wu ◽  
Xin Xu ◽  
Liwei Zhang ◽  
Yingying Huang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factor ◽  
Therapeutic Target ◽  
Potential Prognostic Factor

Upregulation of Trefoil Factor 3 (TFF3) After Rectal Cancer Chemoradiotherapy Is an Adverse Prognostic Factor and a Potential Therapeutic Target

2012 ◽  
Vol 84 (5) ◽  
pp. 1151-1158 ◽  
Author(s):  
Enrique Casado ◽  
Victor Moreno Garcia ◽  
Jose Javier Sánchez ◽  
María Teresa Gómez del Pulgar ◽  
Jaime Feliu ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Prognostic Factor ◽  
Therapeutic Target ◽  
Trefoil Factor ◽  
Potential Therapeutic Target ◽  
Adverse Prognostic Factor ◽  
Trefoil Factor 3

scholarly journals The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

2010 ◽  
Vol 10 (10) ◽  
pp. 1009-1018 ◽  
Author(s):  
Alvarez Hector ◽  
Elizabeth A. Montgomery ◽  
Collins Karikari ◽  
Marcia I. Canto ◽  
Kerry B. Dunbar ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Tyrosine Kinase ◽  
Esophageal Adenocarcinoma ◽  
Receptor Tyrosine Kinase ◽  
Therapeutic Target ◽  
Adverse Prognostic Factor ◽  
Axl Receptor Tyrosine Kinase
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