Does momordica charantia (bitter gourd) improve outcomes in people with type 2 diabetes mellitus?

2012 ◽  

Author(s):  
Cheow Peng Ooi ◽  
Zaitun Yassin ◽  
Tengku-Aizan Hamid


2018 ◽  
Vol 21 (7) ◽  
pp. 672-677 ◽  
Author(s):  
Marisol Cortez-Navarrete ◽  
Esperanza Martínez-Abundis ◽  
Karina G. Pérez-Rubio ◽  
Manuel González-Ortiz ◽  
Miriam Méndez-del Villar


2019 ◽  
Vol 231 ◽  
pp. 311-324 ◽  
Author(s):  
Emanuel L. Peter ◽  
Félicien Mushagalusa Kasali ◽  
Serawit Deyno ◽  
Andrew Mtewa ◽  
Prakash B. Nagendrappa ◽  
...  




2020 ◽  
Author(s):  
Emanuel L. Peter ◽  
Prakash B. Nagendrappa ◽  
Anita Kaligirwa ◽  
Patrick Engeu Ogwang ◽  
Crispin Duncan Sesaazi


2018 ◽  
Vol 7 (1) ◽  
Author(s):  
Emanuel L. Peter ◽  
Serawit Deyno ◽  
Andrew Mtewa ◽  
Félicien Mushagalusa Kasali ◽  
Prakash B. Nagendrappa ◽  
...  


2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Emanuel L. Peter ◽  
Andrew G. Mtewa ◽  
Prakash B. Nagendrappa ◽  
Anita Kaligirwa ◽  
Crispin Duncan Sesaazi

Abstract Background Studies on several preclinical models of type 2 diabetes mellitus have been conducted to establish the hypoglycemic activity of Momordica charantia L. Concerned with appropriateness of these models, we designed a systematic review to establish the efficacy and safety of M. charantia L. in preclinical models of type 2 diabetes mellitus. Methods Review authors will search without language restriction in MEDLINE/PubMed, Web of Science, Embase, Scopus, and CINAHL databases through April 2019. Search filters will be applied to enhance search efficiency. The authors will search for gray literature in Google and Google Scholar, OpenGrey, and ProQuest Dissertations & Theses. Two authors will evaluate full texts, extract data, and asses risk of bias independently. The review will include randomized or non-randomized studies that assessed the efficacy or safety of M. charantia L. with vehicle control group. The primary endpoint will be fasting blood glucose level. We will use Egger’s test to assess publication biases. Chi-square test and I2 will be used to assess heterogeneity in effect size of the primary outcome. Using RevMan software version 5.3, the authors will perform a meta-analysis of quantitative data. Discussion The strength of evidence will be rated as high, moderate, low, or very low using GRADE framework for animal studies. This systematic review will potentially improve research practice by identifying risks of bias and design features that compromise translatability and contribute to evidence-based clinical trial design. Systematic review registration PROSPERO CRD42019119181



2007 ◽  
Vol 60 (6) ◽  
pp. 554-559 ◽  
Author(s):  
Antonio Miguel Limcaco Dans ◽  
Maria Vanessa C. Villarruz ◽  
Cecilia A. Jimeno ◽  
Mark Anthony U. Javelosa ◽  
Joel Chua ◽  
...  




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