Prognostic significance, angiographic characteristics and impact of antithrombotic and anticoagulant therapy on outcomes in high versus low grade coronary artery ectasia: A long-term follow-up study

2018 ◽  
Vol 93 (7) ◽  
pp. 1219-1227 ◽  
Author(s):  
Prasad Gunasekaran ◽  
Dusan Stanojevic ◽  
Taylor Drees ◽  
John Fritzlen ◽  
Megan Haghnegahdar ◽  
...  
Author(s):  
Usama Boles ◽  
Urban Wiklund ◽  
Santhosh David ◽  
Khalid Ahmed ◽  
Michael Y. Henein

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Bengt Wahlin ◽  
Thomas Meedt ◽  
Fredrik Jonsson ◽  
Michael Y. Henein ◽  
Solveig Wållberg-Jonsson

Objective. A long-term follow-up of patients with rheumatoid arthritis (RA) to evaluate factors related to coronary artery calcification (CAC).Methods. All 22 eligible patients (4 males/18 females, mean age 65 years, and RA-duration 30–36 years) from the original (baseline;n=39) study of atherosclerosis were included. Inflammation, cardiovascular risk factors, and biomarkers were measured at baseline. At follow-up 13 years later, CAC was assessed by computed tomography (CT) and the grade of inflammation was measured. Multivariate analysis of differences between patients with low (0–10) and high CAC (>10) was done by orthogonal projection to latent structures (OPLS).Results. Ten patients had CAC 0–10 and 12 had >10 (range 18–1700). Patients with high CAC had significantly higher ESR (24.3 versus 9.9 mm/h) and swollen joint count (2 versus 0). The OPLS models discriminated between patients having high or low CAC. With only baseline variables, the sensitivity was 73% and the specificity 82%. The model that also included inflammatory variables from follow-up had a sensitivity of 89% and a specificity of 85%. Exclusion of baseline intima media thickness and plaque from the latter model modestly reduced the accuracy (sensitivity 80% and specificity 83%).Conclusions. CAC is related to inflammation in patients with RA.


1995 ◽  
Vol 129 (4) ◽  
pp. 663-665 ◽  
Author(s):  
Yves Juillière ◽  
Véronique Berder ◽  
Christine Suty-Selton ◽  
Philippe Buffet ◽  
Nicolas Danchin ◽  
...  

2008 ◽  
Vol 20 (10) ◽  
pp. 966-970 ◽  
Author(s):  
Soo Young Park ◽  
Seong Woo Jeon ◽  
Min Kyu Jung ◽  
Chang Min Cho ◽  
Won Young Tak ◽  
...  

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