Associations of coronary plaque characteristics by integrated backscatter intravascular ultrasound with detectability of vessel external elastic lamina using optical frequency domain imaging in human coronary arteries: A sub‐analysis of the MISTIC‐1 trial

2019 ◽  
Vol 94 (7) ◽  
pp. 947-955 ◽  
Author(s):  
Masato Ishikawa ◽  
Takashi Muramatsu ◽  
Mamoru Nanasato ◽  
Ryo Nagasaka ◽  
Hidemaro Takatsu ◽  
...  
Author(s):  
Satoru Sasaki ◽  
Kenji Nakajima ◽  
Keizo Watanabe ◽  
Yudai Nozaki ◽  
Tadashi Yuguchi ◽  
...  

AbstractThis study aims to test the hypothesis that the effect of excimer laser coronary angioplasty (ELCA) not only vaporizes thrombi and their underlying coronary plaque, it also changes their quality. We performed a series of cross-sectional analyses in 52 lesions in 51 patients before and after ELCA with integrated backscatter-intravascular ultrasound (IB-IVUS). The constituent parts of the plaque can be assessed by IB-IVUS (i.e., calcified, fibrous, lipid) according to integrated backscatter values. Minimum lumen diameter, lumen volume and vessel volume expanded after ELCA, while plaque volume did not significantly decrease. There was also a decrease of ‘lipid’ component (35.4–30.3%, P < 0.001) and an increase of IB-IVUS-derived ‘fibrous’ part (34.5–38.3%, P < 0.001). These results may help in understanding plaque change after ELCA. Excimer laser coronary angioplasty seems to contribute to the modification of coronary plaque composition in addition to debulking it.


2019 ◽  
Vol 42 (6) ◽  
pp. 618-628 ◽  
Author(s):  
Takao Konishi ◽  
Daisuke Sunaga ◽  
Naohiro Funayama ◽  
Tadashi Yamamoto ◽  
Hironori Murakami ◽  
...  

2013 ◽  
Vol 77 (9) ◽  
pp. 2327-2333 ◽  
Author(s):  
Takashi Muramatsu ◽  
Hector M. Garc^|^iacute;a-Garc^|^iacute;a ◽  
Yoshinobu Onuma ◽  
Yao-Jun Zhang ◽  
Christos V. Bourantas ◽  
...  

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