ChemInform Abstract: SYNTHESIS OF HETEROCYCLIC COMPOUNDS USING DIKETENE, ON THE ADDITION REACTION TO THE C=C DOUBLE BOND OF DIKETENE

1974 ◽  
Vol 5 (48) ◽  
pp. no-no
Author(s):  
T. KATO ◽  
M. SATO ◽  
N. KATAGIRI ◽  
Y. KITAGAWA
Keyword(s):  
Double Bond ◽  
Heterocyclic Compounds ◽  
Addition Reaction

Synthesis of Heterocyclic Compounds Using Diketene: On the Addition Reaction to the C=C Double Bond of Diketene

Heterocycles ◽  
1974 ◽  
Vol 2 (2) ◽  
pp. 257 ◽  
Author(s):  
Tetsuzo Kato ◽  
Masayuki Sato ◽  
Nobuya Katagiri ◽  
Yoshinori Kitagawa
Keyword(s):  
Double Bond ◽  
Heterocyclic Compounds ◽  
Addition Reaction

Palladium-mediated cascade or multicomponent reactions: A new route to carbo- and heterocyclic compounds

2006 ◽  
Vol 78 (2) ◽  
pp. 231-239 ◽  
Author(s):  
Geneviève Balme ◽  
Didier Bouyssi ◽  
Nuno Monteiro
Keyword(s):  
Transition Metal ◽  
Intramolecular Cyclization ◽  
Heterocyclic Compounds ◽  
Multicomponent Reactions ◽  
Addition Reaction ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Nucleophiles ◽  
Carbon Carbon Bond

In recent years, new processes based on transition-metal-mediated intramolecular addition reaction of heteronucleophiles and stabilized carbon nucleophiles to unactivated alkenes and alkynes have been developed in our laboratory. In this article, we summarize a number of recent synthetic applications of these new processes. Emphasis is placed on the development of multicomponent reactions based on a Pd-mediated intramolecular cyclization coupled with a carbon-carbon bond-forming reaction. Applications of this methodology to the synthesis of natural lignans are also reported.

Solvent effect on the radical addition reaction to double bond: Experimental and quantum chemical investigations

2005 ◽  
Vol 415 (4-6) ◽  
pp. 202-205 ◽  
Author(s):  
Jacques Lalevée ◽  
Xavier Allonas ◽  
Jean Pierre Fouassier ◽  
Daniel Rinaldi ◽  
Manuel F. Ruiz Lopez ◽  
...  
Keyword(s):  
Double Bond ◽  
Solvent Effect ◽  
Quantum Chemical ◽  
Addition Reaction ◽  
Radical Addition

scholarly journals Synthesis, Characterization and Biological Screening of Azepine Derivative: 2-hydroxy-1,3-di(naphthalene-2-yl)-1H-benzo[b]azepine-5(4H)one

2021 ◽  
Vol 42 (1) ◽  
pp. 75-79
Author(s):  
Amit Sharma ◽  
Ashok Kumar Singh
Keyword(s):  
Heterocyclic Compounds ◽  
Polyphosphoric Acid ◽  
Addition Reaction ◽  
Moderate Activity ◽  
Biological Application ◽  
Numerous Application ◽  
Spectral Techniques ◽  
Antibacterial Assay ◽  
Bacteria And Fungi ◽  
Different Strains

The synthesis of unsaturated heterocyclic compounds containing nitrogen atoms in the ring is very important due to its various biological application in the pharmaceutical industry. Azepine derivatives find numerous application almost every field in medicinal chemistry and some of its are commercially available as drugs. The two-component of azepine derivatives were synthesized by using the aniline and maleic anhydride as a starting material followed by condensation with sodium borohydride in presence of dry benzene, subsequently cyclization by polyphosphoric acid then, finally by an addition reaction with naphthalene-2-ol to form the desired derivative. The formation of the synthesized azepine derivative was confirmed by spectral techniques such as IR, 1H-NMR, and 13C-NMR. The antibacterial assay shows that the synthesized compound (2A) possesses the most highly potent activity in the Bacillus subtilis and moderate activity against other different strains of bacteria and fungi.

scholarly journals 1,6-Naphthyridin-2(1H)-ones: Synthesis and Biomedical Applications

2021 ◽  
Vol 14 (10) ◽  
pp. 1029
Author(s):  
Juan Marcos Oliveras ◽  
Raimon Puig de la Bellacasa ◽  
Roger Estrada-Tejedor ◽  
Jordi Teixidó ◽  
José I. Borrell
Keyword(s):  
Double Bond ◽  
Heterocyclic Compounds ◽  
Biomedical Applications ◽  
The Body ◽  
Synthetic Methods

Naphthyridines, also known as diazanaphthalenes, are a group of heterocyclic compounds that include six isomeric bicyclic systems containing two pyridine rings. 1,6-Naphthyridines are one of the members of such a family capable of providing ligands for several receptors in the body. Among such structures, 1,6-naphthyridin-2(1H)-ones (7) are a subfamily that includes more than 17,000 compounds (with a single or double bond between C3 and C4) included in more than 1000 references (most of them patents). This review will cover the analysis of the diversity of the substituents present at positions N1, C3, C4, C5, C7, and C8 of 1,6-naphthyridin-2(1H)-ones, the synthetic methods used for their synthesis (both starting from a preformed pyridine or pyridone ring), and the biomedical applications of such compounds.

Sign in / Sign up

Export Citation Format

Share Document