Synthesis, Structure-Activity Relationship Studies, and ADMET Properties of 3-Aminocyclohex-2-en-1-ones as Chemokine Receptor 2 (CXCR2) Antagonists

Activity Relationship ◽

Structure Activity ◽

Cxcr2 Antagonists

Discovery, structure-activity relationship study and biological evaluation of 2-thioureidothiophene-3-carboxylates as a novel class of C-X-C chemokine receptor 2 (CXCR2) antagonists

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112387 ◽

2020 ◽

Vol 204 ◽

pp. 112387

Author(s):

Ding Xue ◽

Wenmin Chen ◽

Nouri Neamati

Keyword(s):

Chemokine Receptor ◽

Biological Evaluation ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Cxcr2 Antagonists

Synthesis and Structure−Activity Relationship of the First Nonpeptidergic Inverse Agonists for the Human Cytomegalovirus Encoded Chemokine Receptor US28

10.1021/jm050418d ◽

2005 ◽

Vol 48 (20) ◽

pp. 6461-6471 ◽

Cited By ~ 27

Author(s):

Janneke W. Hulshof ◽

Paola Casarosa ◽

Wiro M. P. B. Menge ◽

Leena M. S. Kuusisto ◽

Henk van der Goot ◽

...

Keyword(s):

Human Cytomegalovirus ◽

Chemokine Receptor ◽

Activity Relationship ◽

Inverse Agonists ◽

Structure Activity ◽

Synthesis and structure–activity relationship of 3-phenyl-3H-quinazolin-4-one derivatives as CXCR3 chemokine receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.03.070 ◽

2005 ◽

Vol 15 (11) ◽

pp. 2910-2913 ◽

Cited By ~ 25

Author(s):

Stefania Storelli ◽

Pauline Verdijk ◽

Dennis Verzijl ◽

Henk Timmerman ◽

Andrea C. van de Stolpe ◽

...

Keyword(s):

Chemokine Receptor ◽

Activity Relationship ◽

Receptor Antagonists ◽

Structure Activity ◽

Structure–Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3)

10.1021/acs.jmedchem.8b00336 ◽

2018 ◽

Vol 61 (8) ◽

pp. 3745-3751 ◽

Cited By ~ 2

Author(s):

Haruka Sekiguchi ◽

Tomoko Kuroyanagi ◽

David Rhainds ◽

Kazuya Kobayashi ◽

Yuka Kobayashi ◽

...

Keyword(s):

Chemokine Receptor ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study

ChemInform Abstract: Structure-Activity Relationship Studies of Natural Product Chemokine Receptor CCR5 Antagonist Anibamine Toward the Development of Novel anti Prostate Cancer Agents.

ChemInform ◽

10.1002/chin.201304150 ◽

2013 ◽

Vol 44 (4) ◽

pp. no-no

Author(s):

Feng Zhang ◽

Christopher K. Arnatt ◽

Kendra M. Haney ◽

Harrison C. Fang ◽

John E. Bajacan ◽

...

Keyword(s):

Prostate Cancer ◽

Natural Product ◽

Chemokine Receptor ◽

Ccr5 Antagonist ◽

Activity Relationship ◽

Structure Activity ◽

Chemokine Receptor Ccr5 ◽

Abstract Structure ◽

Receptor Ccr5

Structure activity relationship studies of natural product chemokine receptor CCR5 antagonist anibamine toward the development of novel anti prostate cancer agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2012.07.049 ◽

2012 ◽

Vol 55 ◽

pp. 395-408 ◽

Cited By ~ 10

Author(s):

Feng Zhang ◽

Christopher K. Arnatt ◽

Kendra M. Haney ◽

Harrison C. Fang ◽

John E. Bajacan ◽

...

Keyword(s):

Prostate Cancer ◽

Natural Product ◽

Chemokine Receptor ◽

Ccr5 Antagonist ◽

Activity Relationship ◽

Structure Activity ◽

Chemokine Receptor Ccr5 ◽

Receptor Ccr5

Discovery and Structure−Activity Relationship of N-(Ureidoalkyl)-Benzyl-Piperidines As Potent Small Molecule CC Chemokine Receptor-3 (CCR3) Antagonists

10.1021/jm0201767 ◽

2002 ◽

Vol 45 (17) ◽

pp. 3794-3804 ◽

Cited By ~ 34

Author(s):

George V. De Lucca ◽

Ui T. Kim ◽

Curt Johnson ◽

Brian J. Vargo ◽

Patricia K. Welch ◽

...

Keyword(s):

Small Molecule ◽

Chemokine Receptor ◽

Activity Relationship ◽

Cc Chemokine ◽

Structure Activity ◽

Structure–Activity Relationship Study of a CXC Chemokine Receptor Type 4 Antagonist, FC131, Using a Series of Alkene Dipeptide Isosteres

10.1021/jm2016914 ◽

2012 ◽

Vol 55 (6) ◽

pp. 2746-2757 ◽

Cited By ~ 23

Author(s):

Kazuya Kobayashi ◽

Shinya Oishi ◽

Ryoko Hayashi ◽

Kenji Tomita ◽

Tatsuhiko Kubo ◽

...

Keyword(s):

Chemokine Receptor ◽

Receptor Type ◽

Activity Relationship ◽

Structure Activity ◽

Cxc Chemokine ◽

Relationship Study ◽

Alkene Dipeptide Isosteres

HIV-1 X4 Activities of Polycationic “Viologen” Based Dendrimers by Interaction with the Chemokine Receptor CXCR4: Study of Structure–Activity Relationship

10.1021/jm301337y ◽

2012 ◽

Vol 55 (23) ◽

pp. 10405-10413 ◽

Cited By ~ 25

Author(s):

Simona Asaftei ◽

Dana Huskens ◽

Dominique Schols

Keyword(s):

Chemokine Receptor ◽

Activity Relationship ◽

Chemokine Receptor Cxcr4 ◽

Structure Activity ◽

Hiv 1

Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽

10.1055/s-0028-1084781 ◽

2008 ◽

Vol 74 (09) ◽

Author(s):

MA Brenzan ◽

CV Nakamura ◽

BPD Filho ◽

T Ueda-Nakamura ◽

MCM Young ◽

...

Keyword(s):

Leishmania Amazonensis ◽

Activity Relationship ◽

Structure Activity ◽