Discovery of quinoline‐derived trifluoromethyl alcohols as antiepileptic and analgesic agents that block sodium channels

Neuronal Sodium Channels in Neurodegeneration and Neuroprotection

PsycEXTRA Dataset ◽

10.1037/e452222006-001 ◽

2003 ◽

Author(s):

Frank C. Tortella ◽

Keyword(s):

Sodium Channels

Medullary epithelial sodium channels (ENAC) participate in cerebral blood flow (CBF) autoregulation

Journal of Cerebral Blood Flow & Metabolism ◽

10.1038/sj.jcbfm.9591524.0190 ◽

2005 ◽

Vol 25 (1_suppl) ◽

pp. S190-S190

Author(s):

Eugene Golanov ◽

Heather Drummond ◽

Jasleen Shant ◽

Benjamin Clower ◽

Betty Chen

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Sodium Channels ◽

Epithelial Sodium Channels

A Multivariate Approach to Analyze Ordinal Data Collected in Clinical Trials of Analgesic Agents

Methods of Information in Medicine ◽

10.1055/s-0038-1636462 ◽

1979 ◽

Vol 18 (03) ◽

pp. 175-179

Author(s):

E. Mabubini ◽

M. Rainisio ◽

V. Mandelli

Keyword(s):

Clinical Trials ◽

Multivariate Analysis ◽

Analgesic Effect ◽

Ordinal Data ◽

Ordinal Scale ◽

Multivariate Approach ◽

Controlled Clinical Trials ◽

Second Stage ◽

Analgesic Agents ◽

Relevant Factors

After pointing out the drawbacks of the approach commonly used to analyze the data collected in controlled clinical trials carried out to evaluate the analgesic effect of potential agents, the authors suggest a procedure suitable for analyzing data coded according to an ordinal scale. In the first stage a multivariate analysis is carried out on the codec! data and the projection of each result in the space of the most relevant factors is obtained. In the second stage the whole set of these values is processed by distribution-free tests. The procedure has been applied to data previously published by VENTAITBIDDA et al. [18].

Pyrethroids and voltage sensors in sodium channels

10.1603/ice.2016.91249 ◽

2016 ◽

Author(s):

Eugenio Eduardo Oliveira

Keyword(s):

Sodium Channels ◽

Voltage Sensors

Faculty Opinions recommendation of BACE1 regulates voltage-gated sodium channels and neuronal activity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088620.542712 ◽

2007 ◽

Author(s):

Mark Fortini

Keyword(s):

Sodium Channels ◽

Neuronal Activity ◽

Voltage Gated ◽

Voltage Gated Sodium Channels

Faculty Opinions recommendation of Menthol pain relief through cumulative inactivation of voltage-gated sodium channels.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13458958.14833058 ◽

2012 ◽

Author(s):

Stuart Bevan

Keyword(s):

Pain Relief ◽

Sodium Channels ◽

Voltage Gated ◽

Voltage Gated Sodium Channels

Faculty Opinions recommendation of Inactivation of sodium channels underlies reversible neuropathy during critical illness in rats.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1567967.1058065 ◽

2010 ◽

Author(s):

Tarek Sharshar

Keyword(s):

Critical Illness ◽

Sodium Channels

Faculty Opinions recommendation of RING finger protein 121 facilitates the degradation and membrane localization of voltage-gated sodium channels.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725357451.793504304 ◽

2015 ◽

Author(s):

Hugues Abriel

Keyword(s):

Sodium Channels ◽

Ring Finger ◽

Membrane Localization ◽

Ring Finger Protein ◽

Voltage Gated ◽

Finger Protein ◽

Voltage Gated Sodium Channels

Faculty Opinions recommendation of Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734643914.793556096 ◽

2019 ◽

Author(s):

Rayaz Malik ◽

Shazli Azmi

Keyword(s):

Sodium Channels ◽

Small Fibre Neuropathy ◽

Gene Screening ◽

Small Fibre

Faculty Opinions recommendation of SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.7358957.7626055 ◽

2010 ◽

Author(s):

Thomas Hund ◽

Nicholas Leymaster

Keyword(s):

Sodium Channels ◽

Macromolecular Complexes ◽

Cardiac Sodium Channels