Cholecystokinin-, galanin-, and corticotropin-releasing factor-like immunoreactive projections from the nucleus of the solitary tract to the parabrachial nucleus in the rat

1990 ◽  
Vol 293 (4) ◽  
pp. 581-598 ◽  
Author(s):  
Horst Herbert ◽  
Clifford B. Saper
Keyword(s):  
Corticotropin Releasing Factor ◽  
Parabrachial Nucleus ◽  
Solitary Tract

A subpopulation of neurons in the rat rostral nucleus of the solitary tract that project to the parabrachial nucleus express glutamate-like immunoreactivity

1999 ◽  
Vol 821 (2) ◽  
pp. 251-262 ◽  
Author(s):  
Carrie F. Gill ◽  
Jean M. Madden ◽  
Bryttnee P. Roberts ◽  
Laurence D. Evans ◽  
Michael S. King
Keyword(s):  
Parabrachial Nucleus ◽  
Solitary Tract ◽  
Rostral Nucleus

Lateral parabrachial lesions attenuate ingestive effects of area postrema lesions

1989 ◽  
Vol 256 (2) ◽  
pp. R306-R312 ◽  
Author(s):  
G. L. Edwards ◽  
R. C. Ritter
Keyword(s):  
Short Duration ◽  
Area Postrema ◽  
Parabrachial Nucleus ◽  
Solitary Tract ◽  
Palatable Food ◽  
Lateral Parabrachial Nucleus ◽  
Ingestive Behaviors

Lesions of the area postrema and adjacent nucleus of the solitary tract (AP lesions) cause rats to consume increased amounts of palatable food in short duration tests. Because the lateral parabrachial nucleus (lPBN) receives a prominent afferent projection from the AP and adjacent nucleus of the solitary tract, it is possible the lPBN plays a role in the altered ingestive behaviors observed in AP-lesioned rats. The present study examines the role of the lPBN in overingestion of highly palatable foods subsequent to AP lesions. We found that lesions of the lPBN alone did not cause rats to consume increased amounts of palatable food. Rather, when lPBN lesions were produced before AP lesions, increased intake of highly palatable food did not occur. Moreover, when AP-lesioned rats received subsequent lPBN lesions, the previously established overingestion of palatable foods was abolished. These results indicate that the lPBN is necessary in the pathogenesis of AP lesion-induced overingestion of highly palatable foods.

Subcortical sites mediating sympathetic responses from insular cortex in rats

1990 ◽  
Vol 258 (1) ◽  
pp. R245-R255 ◽  
Author(s):  
D. F. Cechetto ◽  
S. J. Chen
Keyword(s):  
Insular Cortex ◽  
Lateral Hypothalamic Area ◽  
Parabrachial Nucleus ◽  
Solitary Tract ◽  
Nerve Activity ◽  
Hypothalamic Area ◽  
Renal Nerve ◽  
Lateral Hypothalamic ◽  
Nerve Response ◽  
Renal Nerve Activity

Stimulation of the insular cortex elicits a number of autonomic responses. The insular cortex projects directly to the lateral hypothalamic area, the parabrachial nucleus, and the nucleus of the solitary tract, which in turn project directly to sympathetic preganglionic areas. To determine which of these subcortical sites mediates sympathetic responses evoked from the insular cortex, changes in renal nerve activity were recorded before and after injection of the synaptic blocking agent cobalt into each of these regions. Blood pressure, heart rate, and renal nerve activity were continuously monitored in chloralose or urethan-anesthetized rats. Single-pulse electrical stimulation (200 microA, 1 ms) elicited either an early increase or decrease in renal nerve activity from pressor and depressor sites, respectively, in the insular cortex. Cobalt injections (500 nl) into the lateral hypothalamic area attenuated the nerve response 10-100%. Cobalt injections into the nucleus of the solitary tract significantly enhanced the initial increase in the nerve response obtained from pressor sites in the insular cortex. Injections into the parabrachial nucleus did not affect the nerve responses. These results suggest that there is a mandatory synapse in the lateral hypothalamic area in the pathway from the insular cortex to the sympathetic nervous system.

Demonstration of a bilateral projection from the rostral nucleus of the solitary tract to the medial parabrachial nucleus in rat

1996 ◽  
Vol 737 (1-2) ◽  
pp. 231-237 ◽  
Author(s):  
Justin B Williams ◽  
David M Murphy ◽  
Kathryn E Reynolds ◽  
Sean J Welch ◽  
Michael S King
Keyword(s):  
Parabrachial Nucleus ◽  
Solitary Tract ◽  
Rostral Nucleus ◽  
Bilateral Projection

scholarly journals Taste coding in the parabrachial nucleus of the pons in awake, freely licking rats and comparison with the nucleus of the solitary tract

2014 ◽  
Vol 111 (8) ◽  
pp. 1655-1670 ◽  
Author(s):  
Michael S. Weiss ◽  
Jonathan D. Victor ◽  
Patricia M. Di Lorenzo
Keyword(s):  
Spike Timing ◽  
Temporal Coding ◽  
Parabrachial Nucleus ◽  
Ratio Schedule ◽  
Free Access ◽  
Solitary Tract ◽  
Variable Response ◽  
Response Latencies ◽  
Related Information ◽  
Taste Coding

In the rodent, the parabrachial nucleus of the pons (PbN) receives information about taste directly from the nucleus of the solitary tract (NTS). Here we examined how information about taste quality (sweet, sour, salty, and bitter) is conveyed in the PbN of awake, freely licking rats, with a focus on how this information is transformed from the incoming NTS signals. Awake rats with electrodes in the PbN had free access to a lick spout that delivered taste stimuli (5 consecutive licks; 100 mM NaCl, 10 mM citric acid, 0.01 mM quinine HCl, or 100 mM sucrose and water) or water (as a rinse) on a variable-ratio schedule. To assess temporal coding, a family of metrics that quantifies the similarity of two spike trains in terms of spike count and spike timing was used. PbN neurons ( n = 49) were generally broadly tuned across taste qualities with variable response latencies. Some PbN neurons were quiescent during lick bouts, and others, some taste responsive, showed time-locked firing to the lick pattern. Compared with NTS neurons, spike timing played a larger role in signaling taste in the first 2 s of the response, contributing significantly in 78% (38/49) of PbN cells compared with 45% of NTS cells. Also, information from temporal coding increased at a faster rate as the response unfolded over time in PbN compared with NTS. Collectively, these data suggest that taste-related information from NTS converges in the PbN to enable a subset of PbN cells to carry a larger information load.

Sign in / Sign up

Export Citation Format

Share Document