Urinary human chorionic gonadotropin isoform concentrations in doping control samples

2016 ◽  
Vol 8 (11-12) ◽  
pp. 1147-1151 ◽  
Author(s):  
Anthony W. Butch ◽  
Getachew A. Woldemariam
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Doping Control ◽  
In Doping ◽  
Control Samples

Stabilization of human urine doping control samples: IV. Human chorionic gonadotropin

2010 ◽  
Vol 398 (3) ◽  
pp. 1313-1318 ◽  
Author(s):  
Maria Tsivou ◽  
Helen A. Dimopoulou ◽  
Dimitris G. Georgakopoulos ◽  
Michael Α. Koupparis ◽  
Julia Atta-Politou ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Human Urine ◽  
Doping Control ◽  
Control Samples

Analytic evaluation of the β-human chorionic gonadotropin assay on the Abbott IMx and Elecsys2010 for its use in doping control

2007 ◽  
Vol 40 (16-17) ◽  
pp. 1259-1265 ◽  
Author(s):  
Khurram Shahzad ◽  
Dong-Hyun Kim ◽  
Min-Jung Kang
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Doping Control ◽  
Analytic Evaluation ◽  
In Doping

scholarly journals Performance Characteristic of the β-Human Chorionic Gonadotropin Assay on the Access 2 for Its Use in Doping Control

2010 ◽  
Vol 31 (10) ◽  
pp. 2889-2892 ◽  
Author(s):  
Min-Jung Kang ◽  
Hye-Im Lee ◽  
Sang-Mi Shin ◽  
Hye-Hyun Yoo ◽  
Oh-Seung Kwon ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Performance Characteristic ◽  
Doping Control ◽  
In Doping

scholarly journals Targeting the administration of ecdysterone in doping control samples

2019 ◽  
Vol 38 (1) ◽  
pp. 172-184 ◽  
Author(s):  
Maria Kristina Parr ◽  
Gabriella Ambrosio ◽  
Bernhard Wuest ◽  
Monica Mazzarino ◽  
Xavier de la Torre ◽  
...  
Keyword(s):  
Doping Control ◽  
In Doping ◽  
Control Samples

Analysis of luteinizing hormone (LH): Validation of a commercial ELISA kit for LH analysis and quantification in doping control samples

2020 ◽  
Vol 12 (2) ◽  
pp. 239-246 ◽  
Author(s):  
Riika Mäkelä ◽  
Antti Leinonen ◽  
Tina Suominen
Keyword(s):  
Luteinizing Hormone ◽  
Doping Control ◽  
Elisa Kit ◽  
In Doping ◽  
Control Samples

Comparison of newly developed immuno-MS method with existing DELFIA®immunoassay for human chorionic gonadotropin determination in doping analysis

Bioanalysis ◽  
2013 ◽  
Vol 5 (5) ◽  
pp. 623-630 ◽  
Author(s):  
Hanne Lund ◽  
Ann Helene Snilsberg ◽  
Trine Grønhaug Halvorsen ◽  
Peter Hemmersbach ◽  
Léon Reubsaet
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Doping Analysis ◽  
In Doping

scholarly journals Urine Caffeine Concentration in Doping Control Samples from 2004 to 2015

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 286 ◽  
Author(s):  
Millán Aguilar-Navarro ◽  
Gloria Muñoz ◽  
Juan Salinero ◽  
Jesús Muñoz-Guerra ◽  
María Fernández-Álvarez ◽  
...  
Keyword(s):  
Monitoring Program ◽  
Doping Control ◽  
Urine Samples ◽  
Ergogenic Effect ◽  
Caffeine Concentration ◽  
In Doping ◽  
The World ◽  
World Anti Doping Agency ◽  
Individual Sports ◽  
Control Samples

The ergogenic effect of caffeine is well-established, but the extent of its consumption in sport is unknown at the present. The use of caffeine was considered “prohibited” until 2004, but this stimulant was moved from the List of Prohibited Substances to the Monitoring Program of the World Anti-Doping Agency to control its use by monitoring urinary caffeine concentration after competition. However, there is no updated information about the change in the use of caffeine as the result of its inclusion in the Monitoring Program. The aim of this study was to describe the changes in urine caffeine concentration from 2004 to 2015. A total of 7488 urine samples obtained in official competitions held in Spain and corresponding to athletes competing in Olympic sports (2788 in 2004, 2543 in 2008, and 2157 in 2015) were analyzed for urine caffeine concentration. The percentage of samples with detectable caffeine (i.e., >0.1 μg/mL) increased from ~70.1%, in 2004–2008 to 75.7% in 2015. The median urine caffeine concentration in 2015 (0.85 μg/mL) was higher when compared to the median value obtained in 2004 (0.70 μg/mL; p < 0.05) and in 2008 (0.70 μg/mL; p < 0.05). The urine caffeine concentration significantly increased from 2004 to 2015 in aquatics, athletics, boxing, judo, football, weightlifting, and rowing (p < 0.05). However, the sports with the highest urine caffeine concentration in 2015 were cycling, athletics, and rowing. In summary, the concentration of caffeine in the urine samples obtained after competition in Olympic sports in Spain increased from 2004 to 2015, particularly in some disciplines. These data indicate that the use of caffeine has slightly increased since its removal from the list of banned substances, but urine caffeine concentrations suggest that the use of caffeine is moderate in most sport specialties. Athletes of individual sports or athletes of sports with an aerobic-like nature are more prone to using caffeine in competition.

Fluorescence flow cytometer to determine urine particle reference intervals in doping control samples

2011 ◽  
Vol 213 (1-3) ◽  
pp. 95-100 ◽  
Author(s):  
Neil Robinson ◽  
Pierre-Edouard Sottas ◽  
Martial Saugy
Keyword(s):  
Reference Intervals ◽  
Flow Cytometer ◽  
Doping Control ◽  
In Doping ◽  
Control Samples

scholarly journals Immunoprocedures for detecting human chorionic gonadotropin: clinical aspects and doping control

1997 ◽  
Vol 43 (7) ◽  
pp. 1293-1298 ◽  
Author(s):  
Ulf-Håkan Stenman ◽  
Leila Unkila-Kallio ◽  
Juha Korhonen ◽  
Henrik Alfthan
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Major Part ◽  
Doping Control ◽  
Molecular Forms ◽  
Clinical Aspects ◽  
Serum Samples ◽  
Low Concentrations ◽  
Serum And Urine

Abstract The pregnancy hormone human chorionic gonadotropin (hCG) is also present at low concentrations in plasma and urine of men and nonpregnant women. hCG immunoreactivity occurs in various molecular forms: Besides the intact hCG heterodimer, considerable amounts of proteolytically cleaved forms, free subunits, and fragments are found in plasma and urine. Especially in urine, proteolytic fragments constitute a major part of the hCG immunoreactivity. The different forms of hCG cross-react to various degrees in immunoassays and constitute a problem for standardization of specific hCG determinations. After injection of hCG (10 000 IU of Pregnyl®; Organon), above-normal concentrations of hCG can be detected in serum and urine for 7–11 days. Most immunoassays for hCG also measure hCGβ. Quantitative hCG determinations are mainly performed on serum samples, and very few commercial hCG determinations have been validated for determination of urine samples. Considerable care must therefore be exercised when utilizing such assays to analyze urines for doping control.

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