Social, policy, and public health perspectives on new psychoactive substances

2011 ◽  
Vol 3 (7-8) ◽  
pp. 515-523 ◽  
Author(s):  
H.R. Sumnall ◽  
M. Evans-Brown ◽  
J. McVeigh
Keyword(s):  
Public Health ◽  
Social Policy ◽  
New Psychoactive Substances ◽  
Psychoactive Substances

scholarly journals Metabolomics predicts the pharmacological profile of new psychoactive substances

2018 ◽  
Vol 33 (3) ◽  
pp. 347-354 ◽  
Author(s):  
Eulàlia Olesti ◽  
Ilario De Toma ◽  
Johannes G Ramaekers ◽  
Tibor M Brunt ◽  
Marcel·lí Carbó ◽  
...  
Keyword(s):  
Public Health ◽  
Steroid Hormones ◽  
Learning Algorithm ◽  
New Drugs ◽  
New Psychoactive Substances ◽  
Psychoactive Substances ◽  
Pharmacological Profile ◽  
Monoamine Neurotransmitters ◽  
Drug Risk ◽  
Policy Information

Background: The unprecedented proliferation of new psychoactive substances (NPS) threatens public health and challenges drug policy. Information on NPS pharmacology and toxicity is, in most cases, unavailable or very limited and, given the large number of new compounds released on the market each year, their timely evaluation by current standards is certainly challenging. Aims: We present here a metabolomics-targeted approach to predict the pharmacological profile of NPS. Methods: We have created a machine learning algorithm employing the quantification of monoamine neurotransmitters and steroid hormones in rats to predict the similarity of new drugs to classical ones of abuse (MDMA (3,4-methyl enedioxy methamphetamine), methamphetamine, cocaine, heroin and Δ9-tetrahydrocannabinol). Results: We have characterized each classical drug of abuse and two examples of NPS (mephedrone and JWH-018) following alterations observed in the targeted metabolome profile (monoamine neurotransmitters and steroid hormones) in different brain areas, plasma and urine at 1 h and 4 h post drug/vehicle administration. As proof of concept, our model successfully predicted the pharmacological profile of a synthetic cannabinoid (JWH-018) as a cannabinoid-like drug and synthetic cathinone (mephedrone) as a MDMA-like psychostimulant. Conclusion: Our approach allows a fast NPS pharmacological classification which will benefit both drug risk evaluation policies and public health.

New psychoactive substances: challenges for drug surveillance, control, and public health responses

The Lancet ◽  
2019 ◽  
Vol 394 (10209) ◽  
pp. 1668-1684 ◽  
Author(s):  
Amy Peacock ◽  
Raimondo Bruno ◽  
Natasa Gisev ◽  
Louisa Degenhardt ◽  
Wayne Hall ◽  
...  
Keyword(s):  
Public Health ◽  
New Psychoactive Substances ◽  
Psychoactive Substances ◽  
Drug Surveillance

NEW PSYCHOACTIVE SUBSTANCES AS A CRIME OBJECT

2017 ◽  
pp. 258
Author(s):  
Arnis Slesars ◽  
Aija Jermacāne
Keyword(s):  
Public Health ◽  
United Nations ◽  
Criminal Liability ◽  
New Psychoactive Substances ◽  
Psychoactive Substance ◽  
Psychoactive Substances ◽  
New Psychoactive Substance ◽  
Advantages And Disadvantages ◽  
Public Health Threat ◽  
History Of

A new psychoactive substance is defined as a new narcotic or psychotropic drug, in pure form or in preparation, that is not controlled by the United Nations drug conventions (1961, 1971), but which may pose a public health threat comparable to that posed by substances listed in these conventions. The author researched and analyzed: 1.History of new psychoactive substances in Latvia; 2.Legislative approaches for restricting new psychoactive substances in Latvia; 3.Advantages and disadvantages of criminal liability against new psychoactive substances in Latvia.

scholarly journals New psychoactive substances: a public health issue

2017 ◽  
Vol 25 (5) ◽  
pp. 323-325 ◽  
Author(s):  
Amira Guirguis
Keyword(s):  
Public Health ◽  
Health Issue ◽  
Public Health Issue ◽  
New Psychoactive Substances ◽  
Psychoactive Substances

HCV prevalence and risk behaviours among injectors of new psychoactive substances in a risk environment in Hungary—An expanding public health burden

2017 ◽  
Vol 41 ◽  
pp. 1-7 ◽  
Author(s):  
Anna Tarján ◽  
Mária Dudás ◽  
Lucas Wiessing ◽  
Gergely Horváth ◽  
Erzsébet Rusvai ◽  
...  
Keyword(s):  
Public Health ◽  
New Psychoactive Substances ◽  
Risk Behaviours ◽  
Psychoactive Substances ◽  
Risk Environment ◽  
Public Health Burden ◽  
Health Burden ◽  
Hcv Prevalence

Getting up to speed with the public health and regulatory challenges posed by new psychoactive substances in the information age

Addiction ◽  
2013 ◽  
Vol 108 (10) ◽  
pp. 1700-1703 ◽  
Author(s):  
Paul Griffiths ◽  
Michael Evans-Brown ◽  
Roumen Sedefov
Keyword(s):  
Public Health ◽  
Information Age ◽  
New Psychoactive Substances ◽  
Psychoactive Substances ◽  
The Public ◽  
Regulatory Challenges

scholarly journals Head shops and new psychoactive substances: a public health perspective

2021 ◽  
pp. 1-8
Author(s):  
B. P Smyth
Keyword(s):  
Public Health ◽  
Addiction Treatment ◽  
New Psychoactive Substances ◽  
Psychoactive Substances ◽  
Drug Problem ◽  
Public Health Perspective ◽  
General Hospitals ◽  
Irish Government

In 2010, Ireland found itself at the eye of an international storm as a network of head shops emerged selling new psychoactive substances (NPS) and Irish youth rapidly became the heaviest users of NPS in Europe. Within months, the Irish government enacted novel legislation, which has since been copied by other countries, which effectively stopped the head shops selling NPS. Critics of this policy argued that it could cause harms to escalate. A number of separate studies indicate that a range of drug-related harms increased amongst Irish youth during the period of head shop expansion. Within months of their closure, health harms began to decline. NPS-related addiction treatment episodes reduced and admissions to both psychiatric and general hospitals related to any drug problem began to fall. Population use underwent sustained decline. Consequently, the closure of head shops can be viewed as a success in terms of public health.

“New Psychoactive Substances” (NPS)

2016 ◽  
Vol 49 (03) ◽  
Author(s):  
A Goebel
Keyword(s):  
New Psychoactive Substances ◽  
Psychoactive Substances

Voltammetric profiling of new psychoactive substances: Piperazine derivatives

2021 ◽  
Vol 883 ◽  
pp. 115054
Author(s):  
D. Martins ◽  
E.M.P.J. Garrido ◽  
F. Borges ◽  
J.M.P.J. Garrido
Keyword(s):  
New Psychoactive Substances ◽  
Psychoactive Substances ◽  
Piperazine Derivatives

scholarly journals Mortality involving New Psychoactive Substances across Europe, 2016- 2017

2021 ◽  
pp. 100016
Author(s):  
Hugo López-Pelayo ◽  
Julian Vicente ◽  
Ana Gallegos ◽  
Andrew McAuley ◽  
Yacin Buyuk ◽  
...  
Keyword(s):  
New Psychoactive Substances ◽  
Psychoactive Substances
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