scholarly journals New psychoactive substances: a public health issue

2017 ◽  
Vol 25 (5) ◽  
pp. 323-325 ◽  
Author(s):  
Amira Guirguis
Keyword(s):  
Public Health ◽  
Health Issue ◽  
Public Health Issue ◽  
New Psychoactive Substances ◽  
Psychoactive Substances

Identifying changes in trends in the age standardized incidence of melanoma in Australia

2019 ◽  
Vol 3 (4) ◽  
pp. 250-252 ◽  
Author(s):  
David M Hille
Keyword(s):  
Public Health ◽  
Linear Regression ◽  
Iterative Process ◽  
Linear Trend ◽  
Piecewise Linear ◽  
Health Issue ◽  
Public Health Issue ◽  
Piecewise Linear Regression ◽  
Significant Public Health ◽  
Males And Females

ObjectiveTo identify changes in the linear trend of the age-standardized incidence of melanoma in Australia for all persons, males, and females. MethodsA two-piece piecewise linear regression was fitted to the data. The piecewise breakpoint varied through an iterative process to determine the model that best fits the data.ResultsStatistically significant changes in the trendof the age-standardized incidence of melanoma in Australia were found for all persons, males, and females. The optimal breakpoint for all persons and males was at 1998. For females, the optimal breakpoint was at 2005. The trend after these breakpoints was flatter than prior to the breakpoints, but still positive.ConclusionMelanoma is a significant public health issue in Australia. Overall incidence continues to increase. However, the rate at which the incidence is increasing appears to be decreasing.

Sex Segregation in Sports as a Public Health Issue

2017 ◽  
Author(s):  
Nancy Leong ◽  
Emily Bartlett
Keyword(s):  
Public Health ◽  
Sex Segregation ◽  
Health Issue ◽  
Public Health Issue

Somatisation disorder: a major public health issue

1995 ◽  
Vol 163 (10) ◽  
pp. 558-558 ◽  
Author(s):  
John L Quintner
Keyword(s):  
Public Health ◽  
Health Issue ◽  
Public Health Issue ◽  
Major Public Health Issue ◽  
Somatisation Disorder

The Other View of Disposable Diapers

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 350-351
Author(s):  
ROBERT L. CAMPBELL
Keyword(s):  
Public Health ◽  
Solid Wastes ◽  
Health Hazards ◽  
The Other ◽  
Health Issue ◽  
Public Health Issue ◽  
Public Health Hazards ◽  
Disposable Diapers

To The Editor.— I'm writing to you to express my extreme disappointment at the publication of the commentary titled "Baby Bottoms and Environmental Conundrums: Disposable Diapers and the Pediatrician" that appeared in the August 1991 issue of Pediatrics.1 Public Health Issue About Diaper Disposal. The authors have treated briefly the issue of public health and diaper disposal.1,p387 The reader is left with a perception that discarded diapers pose public health hazards. While the issue of public health and the disposal of diapers and other solid wastes is important, it is treated neither adequately nor fairly in this commentary.

scholarly journals Metabolomics predicts the pharmacological profile of new psychoactive substances

2018 ◽  
Vol 33 (3) ◽  
pp. 347-354 ◽  
Author(s):  
Eulàlia Olesti ◽  
Ilario De Toma ◽  
Johannes G Ramaekers ◽  
Tibor M Brunt ◽  
Marcel·lí Carbó ◽  
...  
Keyword(s):  
Public Health ◽  
Steroid Hormones ◽  
Learning Algorithm ◽  
New Drugs ◽  
New Psychoactive Substances ◽  
Psychoactive Substances ◽  
Pharmacological Profile ◽  
Monoamine Neurotransmitters ◽  
Drug Risk ◽  
Policy Information

Background: The unprecedented proliferation of new psychoactive substances (NPS) threatens public health and challenges drug policy. Information on NPS pharmacology and toxicity is, in most cases, unavailable or very limited and, given the large number of new compounds released on the market each year, their timely evaluation by current standards is certainly challenging. Aims: We present here a metabolomics-targeted approach to predict the pharmacological profile of NPS. Methods: We have created a machine learning algorithm employing the quantification of monoamine neurotransmitters and steroid hormones in rats to predict the similarity of new drugs to classical ones of abuse (MDMA (3,4-methyl enedioxy methamphetamine), methamphetamine, cocaine, heroin and Δ9-tetrahydrocannabinol). Results: We have characterized each classical drug of abuse and two examples of NPS (mephedrone and JWH-018) following alterations observed in the targeted metabolome profile (monoamine neurotransmitters and steroid hormones) in different brain areas, plasma and urine at 1 h and 4 h post drug/vehicle administration. As proof of concept, our model successfully predicted the pharmacological profile of a synthetic cannabinoid (JWH-018) as a cannabinoid-like drug and synthetic cathinone (mephedrone) as a MDMA-like psychostimulant. Conclusion: Our approach allows a fast NPS pharmacological classification which will benefit both drug risk evaluation policies and public health.

Breastfeeding—A Public Health Issue, Not Just a Matter of Choice

2012 ◽  
Vol 7 (2) ◽  
pp. 67-68 ◽  
Author(s):  
Ruth A. Lawrence
Keyword(s):  
Public Health ◽  
Health Issue ◽  
Public Health Issue
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