scholarly journals Left ventricular dimensions and cardiovascular outcomes in systolic heart failure: the WARCEF trial

2021 ◽  
Author(s):  
Kazato Ito ◽  
Siyuan Li ◽  
Shunichi Homma ◽  
John L.P. Thompson ◽  
Richard Buchsbaum ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systolic Heart Failure ◽  
Left Ventricular ◽  
Cardiovascular Outcomes ◽  
Left Ventricular Dimensions ◽  
Ventricular Dimensions

Heart failure with preserved ejection fraction (diastolic heart failure)

2012 ◽  
Vol 153 (51) ◽  
pp. 2030-2040 ◽  
Author(s):  
István Czuriga ◽  
Attila Borbély ◽  
Dániel Czuriga ◽  
Zoltán Papp ◽  
István Édes
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Ejection Fraction ◽  
Diastolic Dysfunction ◽  
Diastolic Heart Failure ◽  
Left Ventricular ◽  
Preserved Ejection Fraction ◽  
Normal Left Ventricular ◽  
Left Ventricular Dimensions ◽  
Ventricular Dimensions

Diastolic heart failure, which is also called as heart failure with preserved ejection fraction, is a clinical syndrome in which patients have signs and symptoms of heart failure, normal or near normal left ventricular ejection fraction (≥50%) and evidence of diastolic dysfunction. Recent epidemiological studies have demonstrated that more than half of all heart failure patients have diastolic heart failure. The syndrome is more common in women than in men and the prevalence increases with age. Patients with diastolic heart failure form a fairly heterogeneous group with complex pathophysiologic mechanisms. The disease is often in association with other comorbidities, such as hypertension, diabetes mellitus or obesity. The diagnosis of diastolic heart failure is best achieved by two-dimensional and Doppler echocardiography, which can detect abnormal myocardial relaxation, decreased compliance and increased filling pressure in the setting of normal left ventricular dimensions and preserved ejection fraction. Unlike heart failure with reduced ejection fraction, there is no such an evidence-based treatment for heart failure with preserved ejection fraction, which would improve clinical outcomes. Thus, pharmacological therapy of diastolic heart failure is based mainly on empiric data, and aims to the normalization of blood pressure, reduction of left ventricular dimensions and increased heart rate, maintenance of normal atrial contraction and treatment of symptoms caused by congestion. Beneficial effects of angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers may be utilized in patients with diastolic dysfunction, especially in those with hypertension. Beta-blockers appear to be useful in lowering heart rate and thereby prolonging left ventricular diastolic filling time, while diuretic therapy is the mainstay of treatment for preventing pulmonary congestion. Nonetheless, treatment of the underlying disease is also an important therapeutic approach. This review summarizes the state of current knowledge with regard to diastolic heart failure. Orv. Hetil., 2012, 153, 2030–2040.

Effects of molsidomine on left ventricular dimensions and cardiac function in patients with chronic heart failure

1985 ◽  
Vol 109 (3) ◽  
pp. 691-693 ◽  
Author(s):  
Guy M. Berkenboom ◽  
John C. Sobolski ◽  
Pol P. Vandermoten ◽  
Eric E. Stoupel ◽  
Serge G. Degre
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Cardiac Function ◽  
Left Ventricular ◽  
Left Ventricular Dimensions ◽  
Ventricular Dimensions

Remodelling is inversely proportional to left ventricular dimensions in a real-life population of patients with chronic heart failure after therapy with sacubitril/valsartan

2021 ◽  
pp. 1-6
Author(s):  
Michele Correale ◽  
Adriana Mallardi ◽  
Lucia Tricarico ◽  
Pietro Mazzeo ◽  
Armando Ferraretti ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Real Life ◽  
Left Ventricular ◽  
Left Ventricular Dimensions ◽  
Ventricular Dimensions

Beneficial effects on left ventricular dimensions and function during β-blockade with metoprolol in the treatment of chronic heart failure

2000 ◽  
Vol 2 ◽  
pp. 23-23
Author(s):  
B.A. Groenning ◽  
J.C. Nilsson ◽  
H.B.W. Larson ◽  
L. Sondergaard ◽  
T. Fritz-Hansen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Left Ventricular ◽  
Beneficial Effects ◽  
Left Ventricular Dimensions ◽  
And Function ◽  
Ventricular Dimensions

Changes in left ventricular dimensions and performance resulting from acute and chronic volume overload in the conscious dog

1983 ◽  
Vol 61 (11) ◽  
pp. 1274-1280 ◽  
Author(s):  
Israel Belenkie ◽  
John S. Baumber ◽  
Alfred Rademaker
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Systolic Function ◽  
Volume Overload ◽  
Left Ventricular ◽  
Shortening Velocity ◽  
Left Ventricular Dimensions ◽  
And Performance ◽  
Fractional Shortening ◽  
Ventricular Dimensions

A previously described animal model with an aorta to left atrium shunt has been modified to assess changes in left ventricular dimensions and performance resulting from volume overload of the left ventricle and to determine if any of these changes can predict outcome. In eight surviving dogs, end-diastolic and end-systolic diameters and estimated stroke volume increased rapidly in a curvilinear fashion over approximately 60 days with no significant changes thereafter. Mean normalized circumferential fibre shortening velocity was slightly less than and fractional shortening was similar to the controls; the changes in both indices were parallel to those in the controls. In five dogs that died 5–18 days postoperatively in congestive heart failure, none of the measurements obtained could be used to predict the outcome; the changes in the left ventricular diameters were similar to those in the survivors and systolic function was either normal or enhanced.

scholarly journals ANP & BNP are potent markers for left ventricular dimensions, mass and function in patients with chronic heart failure

2000 ◽  
Vol 2 ◽  
pp. 28-28
Author(s):  
B.A. Groenning ◽  
J.C. Nilsson ◽  
L. Sondergaard ◽  
A. Kjaer ◽  
T. Fritz-Hansen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Left Ventricular ◽  
Left Ventricular Dimensions ◽  
And Function ◽  
Ventricular Dimensions
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