A randomised, double‐blind, placebo‐controlled trial of metformin on myocardial efficiency in insulin‐resistant chronic heart failure patients without diabetes

Anders Hostrup Larsen; Niels Jessen; Helene Nørrelund; Lars Poulsen Tolbod; Hendrik Johannes Harms; Søren Feddersen; Flemming Nielsen; Kim Brøsen; Nils Henrik Hansson; Jørgen Frøkiær; Steen Hvitfeldt Poulsen; Jens Sörensen; Henrik Wiggers

doi:10.1002/ejhf.1656

A randomised, double‐blind, placebo‐controlled trial of metformin on myocardial efficiency in insulin‐resistant chronic heart failure patients without diabetes

European Journal of Heart Failure ◽

10.1002/ejhf.1656 ◽

2019 ◽

Vol 22 (9) ◽

pp. 1628-1637 ◽

Cited By ~ 8

Author(s):

Anders Hostrup Larsen ◽

Niels Jessen ◽

Helene Nørrelund ◽

Lars Poulsen Tolbod ◽

Hendrik Johannes Harms ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo ◽

Heart Failure Patients ◽

Insulin Resistant ◽

Myocardial Efficiency

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The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chronic heart failure and diabetes or prediabetes (Met-HeFT)

American Heart Journal ◽

10.1016/j.ahj.2020.09.020 ◽

2021 ◽

Vol 231 ◽

pp. 137-146

Author(s):

Henrik Wiggers ◽

Lars Køber ◽

Gunnar Gislason ◽

Morten Schou ◽

Mikael Kjær Poulsen ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Isosorbide Dinitrate ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo ◽

Factorial Trial

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Effect of liraglutide, a glucagon-like peptide-1 analogue, on left ventricular function in stable chronic heart failure patients with and without diabetes (LIVE)-a multicentre, double-blind, randomised, placebo-controlled trial

European Journal of Heart Failure ◽

10.1002/ejhf.657 ◽

2016 ◽

Vol 19 (1) ◽

pp. 69-77 ◽

Cited By ~ 174

Author(s):

Anders Jorsal ◽

Caroline Kistorp ◽

Pernille Holmager ◽

Rasmus Stilling Tougaard ◽

Roni Nielsen ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Left Ventricular Function ◽

Ventricular Function ◽

Controlled Trial ◽

Left Ventricular ◽

Double Blind ◽

Heart Failure Patients ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1

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Influence of angiotensin converting enzyme inhibition on exercise performance and clinical symptoms in chronic heart failure: a multicentre, double-blind, placebo-controlled trial

European Heart Journal ◽

10.1093/eurheartj/14.suppl_c.18 ◽

1993 ◽

Vol 14 (suppl C) ◽

pp. 18-23 ◽

Cited By ~ 12

Author(s):

L. Dossegger ◽

E. Aldor ◽

M. G. Baird ◽

S. Braun ◽

J. G. F. Cleland ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Angiotensin Converting Enzyme ◽

Clinical Symptoms ◽

Controlled Trial ◽

Angiotensin Converting Enzyme Inhibition ◽

Converting Enzyme ◽

Double Blind ◽

Double Blind Placebo ◽

Converting Enzyme Inhibition

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A multi-center, randomized, double-blind, placebo-parallel controlled trial for the efficacy and safety of shenfuqiangxin pills in the treatment of chronic heart failure (Heart-Kidney yang deficiency syndrome)

Medicine ◽

10.1097/md.0000000000020271 ◽

2020 ◽

Vol 99 (21) ◽

pp. e20271 ◽

Cited By ~ 1

Author(s):

Lijun Guo ◽

Hui Yuan ◽

Dawu Zhang ◽

Jian Zhang ◽

Qi Hua ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Controlled Trial ◽

Deficiency Syndrome ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Kidney Yang Deficiency

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Effect of rosuvastatin in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

The Lancet ◽

10.1016/s0140-6736(08)61240-4 ◽

2008 ◽

Vol 372 (9645) ◽

pp. 1231-1239 ◽

Cited By ~ 669

Author(s):

GISSI-HF investigators

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo

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Chinese herbal medicine for chronic heart failure: a multicenter, randomized, double-blind, placebo-controlled trial

Journal of Traditional Chinese Medical Sciences ◽

10.1016/j.jtcms.2014.11.010 ◽

2014 ◽

Vol 1 (2) ◽

pp. 98-108 ◽

Cited By ~ 2

Author(s):

Liangtao Luo ◽

Juan Wang ◽

Aiqing Han ◽

Peng Zhang ◽

Shuzhen Guo ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Herbal Medicine ◽

Chinese Herbal Medicine ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo ◽

Chinese Herbal

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Effect of Yangxinkang Tablets (养心康片) on chronic heart failure: A multi-center randomized double-blind placebo-controlled trial

Chinese Journal of Integrative Medicine ◽

10.1007/s11655-015-2170-x ◽

2015 ◽

Vol 21 (10) ◽

pp. 733-742 ◽

Cited By ~ 3

Author(s):

Shao-xiang Xian ◽

Zhong-qi Yang ◽

Pei-hua Ren ◽

Xiao-han Ye ◽

Sui-lin Ye ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Controlled Trial ◽

Double Blind ◽

Double Blind Placebo

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Faculty Opinions recommendation of Maintenance of serum potassium with sodium zirconium cyclosilicate (ZS-9) in heart failure patients: results from a phase 3 randomized, double-blind, placebo-controlled trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725515440.793511074 ◽

2015 ◽

Author(s):

WH Wilson Tang

Keyword(s):

Heart Failure ◽

Serum Potassium ◽

Controlled Trial ◽

Phase 3 ◽

Double Blind ◽

Double Blind Placebo ◽

Heart Failure Patients ◽

Sodium Zirconium ◽

Sodium Zirconium Cyclosilicate

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Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study

Cardiovascular Drugs and Therapy ◽

10.1007/s10557-020-07050-5 ◽

2020 ◽

Author(s):

Anders Hostrup Larsen ◽

Henrik Wiggers ◽

Ole Lindgård Dollerup ◽

Nichlas Riise Jespersen ◽

Nils Henrik Hansson ◽

...

Keyword(s):

Heart Failure ◽

Body Weight ◽

Insulin Sensitivity ◽

Chronic Heart Failure ◽

Controlled Study ◽

Double Blind ◽

Increase Insulin Sensitivity ◽

Double Blind Placebo ◽

Heart Failure Patients

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PDE 5 inhibition with udenafil improves left ventricular systolic/diastolic functions and exercise capacity in patients with chronic heart failure with reduced ejection fraction; A 12-week, randomized, double-blind, placebo-controlled trial

American Heart Journal ◽

10.1016/j.ahj.2015.03.018 ◽

2015 ◽

Vol 169 (6) ◽

pp. 813-822.e3 ◽

Cited By ~ 21

Author(s):

Kyung-Hee Kim ◽

Hyung-Kwan Kim ◽

In-Chang Hwang ◽

Hyun-Jai Cho ◽

Nari Je ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Ejection Fraction ◽

Exercise Capacity ◽

Controlled Trial ◽

Left Ventricular ◽

Double Blind ◽

Double Blind Placebo ◽

Reduced Ejection Fraction ◽

Diastolic Functions

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