Understanding the importance of low‐molecular weight (ethylene oxide‐ and propylene oxide‐induced) DNA adducts and mutations in risk assessment: Insights from 15 years of research and collaborative discussions

Environmental and Molecular Mutagenesis ◽

10.1002/em.22248 ◽

2018 ◽

Vol 60 (2) ◽

pp. 100-121 ◽

Author(s):

L. H. Pottenger ◽

G. Boysen ◽

K. Brown ◽

J. Cadet ◽

R. P. Fuchs ◽

...

Keyword(s):

Risk Assessment ◽

Molecular Weight ◽

Ethylene Oxide ◽

Dna Adducts ◽

Propylene Oxide ◽

Low Molecular Weight

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13C-NMR of Anionic Low-Molecular-Weight Stat-Poly(Ethylene Oxide-Co-Propylene Oxide): Correlation with Monte Carlo Simulation

International Journal of Polymer Analysis and Characterization ◽

10.1080/10236669508233870 ◽

1995 ◽

Vol 1 (2) ◽

pp. 159-173 ◽

Author(s):

M. F. Llauro ◽

C. Monnet ◽

A. Goux ◽

R. Spitz ◽

T. Hamaide

Keyword(s):

Molecular Weight ◽

Monte Carlo Simulation ◽

Monte Carlo ◽

Ethylene Oxide ◽

Propylene Oxide ◽

13C Nmr ◽

Low Molecular Weight ◽

Poly Ethylene Oxide ◽

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Thermal oxidation of poly(ethylene oxide–propylene oxide–ethylene oxide) triblock copolymer: focus on low molecular weight degradation products

Polymer Degradation and Stability ◽

10.1016/s0141-3910(02)00079-4 ◽

2002 ◽

Vol 77 (1) ◽

pp. 55-66 ◽

Author(s):

Guillaume Gallet ◽

Bengt Erlandsson ◽

Ann-Christine Albertsson ◽

Sigbritt Karlsson

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Thermal Oxidation ◽

Propylene Oxide ◽

Triblock Copolymer ◽

Degradation Products ◽

Low Molecular Weight ◽

Poly Ethylene Oxide ◽

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Propylene oxide-ethylene oxide block copolymers as demulsifiers for water-in-oil emulsions, I. Effect of molecular weight and hydrophilic-lipophylic balance on the demulsification efficiency

Monatshefte für Chemie - Chemical Monthly ◽

10.1007/bf00817254 ◽

1996 ◽

Vol 127 (6-7) ◽

pp. 621-629 ◽

Author(s):

N. N. Zaki ◽

M. E. Abdel-Raouf ◽

A. -A. A. Abdel-Azim

Keyword(s):

Molecular Weight ◽

Block Copolymers ◽

Ethylene Oxide ◽

Propylene Oxide ◽

Oil Emulsions ◽

Demulsification Efficiency

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Isothermal Thickening and Thinning Processes in Low-Molecular-Weight Poly(ethylene oxide) Fractions Crystallized from the Melt. 8. Molecular Shape Dependence. Volume 32, Number 15, July 27, 1999, pp 4784−4793.

Macromolecules ◽

10.1021/ma9824046 ◽

1999 ◽

Vol 32 (15) ◽

pp. 5174-5174

Author(s):

Er-Qiang Chen ◽

Song-Wook Lee ◽

Anqiu Zhang ◽

Bon-Suk Moon ◽

Ian Mann ◽

...

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Molecular Shape ◽

Low Molecular Weight ◽

Shape Dependence ◽

Poly Ethylene Oxide ◽

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Melting behaviour of low molecular weight poly (ethylene-oxide) fractions

Colloid & Polymer Science ◽

10.1007/bf01643767 ◽

1976 ◽

Vol 254 (8) ◽

pp. 695-715 ◽

Author(s):

C. P. Buckley ◽

A. J. Kovacs

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Low Molecular Weight ◽

Melting Behaviour ◽

Poly Ethylene Oxide ◽

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Review for "Safety Risk Management for Low Molecular Weight Process‐related Impurities in Monoclonal Antibody Therapeutics: Categorization, Risk Assessment, Testing Strategy, and Process Development With Leveraging Clearance Potential"

10.1002/btpr.3119/v1/review2 ◽

2020 ◽

Keyword(s):

Risk Assessment ◽

Molecular Weight ◽

Monoclonal Antibody ◽

Risk Management ◽

Process Development ◽

Low Molecular Weight ◽

Testing Strategy ◽

Safety Risk ◽

Antibody Therapeutics ◽

Related Impurities

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Onset of chain folding in low-molecular-weight poly(ethylene oxide) fractions crystallized from the melt

Macromolecules ◽

10.1021/ma00158a032 ◽

1986 ◽

Vol 19 (4) ◽

pp. 1124-1128 ◽

Author(s):

John D. Hoffman

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Low Molecular Weight ◽

Chain Folding ◽

Poly Ethylene Oxide ◽

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Isothermal Thickening and Thinning Processes in Low Molecular Weight Poly(ethylene oxide) Fractions Crystallized from the Melt

ACS Symposium Series - Scattering from Polymers ◽

10.1021/bk-2000-0739.ch008 ◽

1999 ◽

pp. 118-139 ◽

Author(s):

Er-Qiang Chen ◽

Song-Wook Lee ◽

Anqiu Zhang ◽

Bon-Suk Moon ◽

Ian Mann ◽

...

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Low Molecular Weight ◽

Poly Ethylene Oxide ◽

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Crystallinity and fusion of low molecular weight poly(ethylene oxide): effect of end-group

Polymer ◽

10.1016/0032-3861(77)90195-1 ◽

1977 ◽

Vol 18 (8) ◽

pp. 852-854 ◽

Author(s):

M.J. Fraser ◽

D.R. Cooper ◽

C. Booth

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Low Molecular Weight ◽

Poly Ethylene Oxide ◽

Poly Ethylene ◽

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CATIONIC POLYMERIZATION OF ETHYLENE OXIDE: IV. THE PROPAGATION REACTIONS

Canadian Journal of Chemistry ◽

10.1139/v60-265 ◽

1960 ◽

Vol 38 (10) ◽

pp. 1967-1975 ◽

Author(s):

G. T. Merrall ◽

G. A. Latrémouille ◽

A. M. Eastham

Keyword(s):

Molecular Weight ◽

Ethylene Oxide ◽

Cationic Polymerization ◽

Chain Growth ◽

Low Molecular Weight ◽

Studies of the boron-fluoride-catalyzed reaction of ethylene oxide with simple alcohols and low molecular weight polyglycols indicate three ways in which chain growth could occur, but only one of these is considered to be important after the initial stages of polymerization. The rate of disappearance of monomer reaches a maximum at a molecular weight of about 400. A mechanism is proposed to account for both polymerization and depolymerization and it is shown how equilibrium between these two reactions could result.

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