Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2‐induced STAT3 activation

Kouji Izumi; Lei‐Ya Fang; Atsushi Mizokami; Mikio Namiki; Lei Li; Wen‐Jye Lin; Chawnshang Chang

doi:10.1002/emmm.201202367

Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2‐induced STAT3 activation

EMBO Molecular Medicine ◽

10.1002/emmm.201202367 ◽

2013 ◽

Vol 5 (9) ◽

pp. 1383-1401 ◽

Cited By ~ 124

Author(s):

Kouji Izumi ◽

Lei‐Ya Fang ◽

Atsushi Mizokami ◽

Mikio Namiki ◽

Lei Li ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Macrophage Recruitment ◽

Prostate Cancer Metastasis

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Infiltrating T cells promote prostate cancer metastasis via modulation of FGF11→miRNA-541→androgen receptor (AR)→MMP9 signaling

Molecular Oncology ◽

10.1016/j.molonc.2014.07.013 ◽

2014 ◽

Vol 9 (1) ◽

pp. 44-57 ◽

Cited By ~ 42

Author(s):

Shuai Hu ◽

Lei Li ◽

Shuyuan Yeh ◽

Yun Cui ◽

Xin Li ◽

...

Keyword(s):

Prostate Cancer ◽

T Cells ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Prostate Cancer Metastasis

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Abstract 2080: Inhibiting androgen receptor-associated Src signaling by VAL201 inhibits prostate cancer metastasis in an orthotopic mouse model.

10.1158/1538-7445.am2013-2080 ◽

2013 ◽

Author(s):

George S. Morris ◽

Mari I. Suominen ◽

Katja M. Fagerlund ◽

Jukka-Pekka Rissanen ◽

Jussi M. Halleen ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Mouse Model ◽

Cancer Metastasis ◽

Orthotopic Mouse Model ◽

Src Signaling ◽

Prostate Cancer Metastasis

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Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis

Oncogene ◽

10.1038/onc.2017.226 ◽

2017 ◽

Vol 36 (45) ◽

pp. 6213-6224 ◽

Cited By ~ 17

Author(s):

W-Y Chen ◽

Y-C Tsai ◽

M K Siu ◽

H-L Yeh ◽

C-L Chen ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Tumor Promoter ◽

Prostate Cancer Metastasis

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Abstract B31: Characterization of a novel model of prostate cancer metastasis resulting from androgen receptor suppression

10.1158/1538-7445.tummet15-b31 ◽

2016 ◽

Author(s):

Clinton K. Matson ◽

Peter S. Nelson

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Prostate Cancer Metastasis ◽

Novel Model

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231 TETRANDRINE INDUCES CDK INHIBITORS (P21 WAF1/CIP1 AND P27/KIP1) AND SUPPRESSES ANDROGEN RECEPTOR (AR) ACTIVITY TO MODULATE CELL CYCLE AND SUPRESS PROSTATE CANCER METASTASIS

The Journal of Urology ◽

10.1016/j.juro.2010.02.289 ◽

2010 ◽

Vol 183 (4S) ◽

Author(s):

Sweaty Koul ◽

Paul Maroni ◽

Binod Kumar ◽

Randall B. Meacham ◽

Hari Koul

Keyword(s):

Prostate Cancer ◽

Cell Cycle ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Cdk Inhibitors ◽

Prostate Cancer Metastasis ◽

P21 Waf1 ◽

P27 Kip1

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Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling

Cell Death and Disease ◽

10.1038/cddis.2013.270 ◽

2013 ◽

Vol 4 (8) ◽

pp. e764-e764 ◽

Cited By ~ 102

Author(s):

T-H Lin ◽

K Izumi ◽

S O Lee ◽

W-J Lin ◽

S Yeh ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Macrophage Infiltration ◽

Differential Modulation ◽

Prostate Cancer Metastasis

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Upregulation of potential regulatory signaling molecules correlate with androgen receptor splice variants AR-V7 and AR-V567es in prostate cancer metastasis

Gene ◽

10.1016/j.gene.2020.145377 ◽

2021 ◽

Vol 772 ◽

pp. 145377

Author(s):

Ilker Kiliccioglu ◽

Cenk Y. Bilen ◽

Sinan Sozen ◽

Ece Konac

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Splice Variants ◽

Signaling Molecules ◽

Prostate Cancer Metastasis ◽

Androgen Receptor Splice Variants

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Corrigendum to “Infiltrating T cells promote prostate cancer metastasis via modulation of FGF11→miRNA-541→androgen receptor (AR)→MMP9 signaling” [Mol Oncol 9 (1) (2015) 44-57]

Molecular Oncology ◽

10.1016/j.molonc.2016.10.005 ◽

2016 ◽

Vol 10 (10) ◽

pp. 1628-1629 ◽

Cited By ~ 1

Author(s):

Shuai Hu ◽

Lei Li ◽

Shuyuan Yeh ◽

Yun Cui ◽

Xin Li ◽

...

Keyword(s):

Prostate Cancer ◽

T Cells ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Prostate Cancer Metastasis

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MEIS proteins inhibit HOXB13-dependent prostate cancer metastasis and Androgen Receptor signaling

10.26226/morressier.5f69edb69b74b699bf38c682 ◽

2020 ◽

Author(s):

Srikanth Perike

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Receptor Signaling ◽

Androgen Receptor Signaling ◽

Prostate Cancer Metastasis

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Elevation of androgen receptor promotes prostate cancer metastasis by induction of epithelial‐mesenchymal transition and reduction of KAT 5

Cancer Science ◽

10.1111/cas.13776 ◽

2018 ◽

Vol 109 (11) ◽

pp. 3564-3574 ◽

Cited By ~ 10

Author(s):

Ching‐Yu Lin ◽

Yee‐Jee Jan ◽

Li‐Kuo Kuo ◽

Bi‐Juan Wang ◽

Chieh Huo ◽

...

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Cancer Metastasis ◽

Epithelial Mesenchymal Transition ◽

Mesenchymal Transition ◽

Prostate Cancer Metastasis

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