A histological comparison of deep and superficial lobe pleomorphic adenomas of the parotid gland

Head & Neck ◽  
2003 ◽  
Vol 25 (8) ◽  
pp. 649-653 ◽  
Author(s):  
Michael S. Harney ◽  
Colette Murphy ◽  
Stephen Hone ◽  
Mary Toner ◽  
Conrad V. Timon
Keyword(s):  
Parotid Gland ◽  
Superficial Lobe ◽  
Pleomorphic Adenomas

scholarly journals Differentiation of Benign and Malignant Parotid Gland Tumors with MRI and Diffusion Weighted Imaging

2021 ◽  
Author(s):  
Umut Perçem Orhan Söylemez ◽  
Başak Atalay
Keyword(s):  
Parotid Gland ◽  
Signal Intensity ◽  
Perineural Spread ◽  
Adc Value ◽  
Parotid Gland Tumors ◽  
Superficial Lobe ◽  
Adjacent Structures ◽  
Significant Difference ◽  
Pleomorphic Adenomas ◽  
Adc Values

Objective: This study investigated the effectivity of Magnetic Resonance Imaging (MRI) findings and Apparent Diffusion Coefficient (ADC) value in evaluating parotid gland tumors (PGTs), and aimed to reduce the biopsy procedure before surgery. Methods: This retrospective study included 54 PGTs of 42 patients’ (24 female, 18 male, mean age; 51.4±15.9). All of the patients had an MRI, and histopathologic diagnosis. The signal intensity [T1 and T2 Weighted (W), T1W after intravenous contrast agent injection] and mean ADC values of the PGTs were measured. Also contrast enhancement pattern (homogenous, heterogeneous, peripheral or none), margin features (well or ill-defined), sizes, location (superficial lobe/deeplobe/both), perineural spread, presence of lymphadenopathy, and extension to adjacent structures were noted. Results: The distribution of PGTs was; 21 pleomorphic adenomas, 18 Warthin tumors, 2 lymph nodes, 2 mucoepidermoid carcinomas, 5 adenoid cystic carcinoma, 1 basal cell carcinoma,2 metastases and 2 lymphomas; (13 malignant and 41 benign lesions). Morphologic parameters; ill-defined margin, perineural spread, lymphadenopathy, and extension to adjacent structures were found to be significantly associated with malign lesions (p<0.01). There was a significant difference between ADC values of malignant and benign PGTs (p<0.05). Also ADC values and T2 signal intensity was significantly lower in Warthin tumors rather than pleomorphic adenomas (p<0.05). Conclusions: Mean ADC values when considered with morphological features may be accessible methods to distinguish benign and malignant PGTs, also ADC values and T2 signal intensity may be useful for differentiating pleomorphic adenomas from Warthin tumors, thereby reducing the number of biopsies and thus complications.

scholarly journals Etiology and familial inheritance of pleomorphic adenomas

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Krysten Clark
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
White Male ◽  
Salivary Gland Tumor ◽  
Major Salivary Gland ◽  
Gland Tumor ◽  
Superficial Lobe ◽  
Increased Risk ◽  
Pleomorphic Adenomas

Background: A pleomorphic adenoma is the most common salivary gland neoplasm in both children and adults. Pleomorphic adenomas are derived from ductal and myoepithelial cells and are most commonly found in the superficial lobe of the parotid gland. The purpose of this article is to discuss the genes involved in pleomorphic adenomas and the possible autosomal dominant mode of inheritance. Case Description: The first patient was a white male who was diagnosed with carcinoma ex pleomorphic adenoma, a highly aggressive tumor, at the age of 57. He had an undiagnosed pleomorphic adenoma for approximately 15 years prior. The tumor was excised and the patient underwent radiation in the location of his parotid gland for 4 years until he deceased. The second patient is a white female, his daughter, who was diagnosed with a benign pleomorphic adenoma at the age of 46. Her salivary gland tumor was excised and normal follow up appointments occurred. Practical Implications: Pleomorphic adenomas most commonly affect the parotid gland, the largest of the three major salivary gland tumors. Occurrence and excision of this salivary gland tumor will cause a decrease in the secretion of saliva, leading to a dry mouth and an increased risk of caries.

scholarly journals An Exceptional Case of Intraparotid Plexiform Neurofibroma Originating from Autonomic Fibers of the Auriculotemporal Nerve

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Sarantis Blioskas ◽  
Sotiris Sotiriou ◽  
Katerina Rizou ◽  
Triantafyllia Koletsa ◽  
Petros Karkos ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Plexiform Neurofibroma ◽  
Surgical Excision ◽  
Neurofibromatosis Type ◽  
Exceptional Case ◽  
Benign Tumors ◽  
First Case ◽  
Superficial Lobe ◽  
The Right ◽  
Auriculotemporal Nerve

Plexiform neurofibromas are benign tumors that tend to occur in patients suffering from neurofibromatosis type 1 (NF-1). This report addresses a rare case where the tumor affected the parotid gland, deriving almost exclusively from the peripheral portion of the facial nerve. A 6-year-old male was referred to us complaining about a gradually enlarging swelling over the right parotid area. Imaging localized the lesion to the superficial lobe of the parotid gland, suggesting a neurofibroma. Cosmetic disfigurement and a functional deficit led us to perform complete surgical resection. Meticulous surgical dissection as well as auriculotemporal nerve origin made complete extirpation possible with almost zero morbidity and ensured alleviation of both aesthetic impairment and pain. This is the first case of an intraparotid PN in a pediatric NF-1 patient, which originated from branches of the auriculotemporal nerve and particularly from fibers of the autonomic nervous system. Radical surgical excision was decided according to established decision-making algorithms.

Intraluminal crystalloids in malignant salivary gland tumours

1987 ◽  
Vol 101 (11) ◽  
pp. 1175-1181 ◽  
Author(s):  
Jae Y. Ro ◽  
Bruce Mackay ◽  
John G. Batsakis ◽  
Joiner Cartwright
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Parotid Glands ◽  
Salivary Duct ◽  
X Ray ◽  
Salivary Gland Tumours ◽  
Pleomorphic Adenomas

AbstractThe ultrastructural, X-ray microanalytical, histochemical and immunocytochemi-cal features of intraluminal crystalloids found in adenocarcinomas of the parotid gland have been studied. The crystalloids, putatively derived from an abnormal crystalization of salivary duct proteins, are considerably different from the crystalloids found in normal parotid glands, pleomorphic adenomas, and sialocysts.

Synchronous unilateral pleomorphic adenomas in the parotid gland: report of a case

2009 ◽  
Vol 47 (2) ◽  
pp. 155-156 ◽  
Author(s):  
Darryl M. Coombes ◽  
Reem Kaddour ◽  
Neil Shah
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenomas

High-Grade Mucoepidermoid Carcinoma Ex Metastasizing Pleomorphic Adenomas in the Parotid Gland and Parapharyngeal Space: a Case Report and Literature Review

2021 ◽  
Vol 25 (3) ◽  
pp. 201
Author(s):  
Eun Ji Lee ◽  
Ha Young Lee ◽  
Suk Jin Choi ◽  
Myung Kwan Lim ◽  
Young Hye Kang
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Parotid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Parapharyngeal Space ◽  
High Grade ◽  
Pleomorphic Adenomas

Surgical Anatomy of the Parotid Gland

2021 ◽  
pp. 13-23
Keyword(s):  
Parotid Gland ◽  
Facial Nerve ◽  
External Auditory Meatus ◽  
Styloid Process ◽  
Terminal Segment ◽  
External Carotid Artery ◽  
Surgical Anatomy ◽  
Mastoid Process ◽  
External Carotid ◽  
Superficial Lobe

The parotid gland consists of two lobes: superficial and deep with regard to its relation with the facial nerve. It is wrapped around the mandibular ramus and secretes saliva through the parotid (Stensen's) duct. It is a paired organ, weighing 15-30g each. Its superficial lobe overlies the lateral surface of the masseter muscle and is bounded superiorly by the zygomatic arch, while its deep lobe is located in the pre-styloid compartment of the parapharyngeal space between the mastoid process posteriorly, ramus of mandible anteriorly, and external auditory meatus superiorly. Medially, the gland reaches to the styloid process. Inferiorly, the parotid tail extends down to the anteromedial margin of sternocleido-mastoid muscle. Several structures run through the parotid gland, namely, terminal segment of external carotid artery, retro-mandibular vein, parotid lymph nodes, and facial nerve, which soon gives two divisions (temporo-facial and cervico-facial) that give off five branches inside the gland radiating forwards. This chapter explores the surgical anatomy of the parotid gland.

Huge Lipoma of the Right Parotid Gland: Case Report and Review of 42 Cases

2016 ◽  
Vol 95 (1) ◽  
pp. E8-E13 ◽  
Author(s):  
Timuçin Baykul ◽  
M. Asım Aydın ◽  
Yavuz Fındık ◽  
Derya Yıldırım
Keyword(s):  
Differential Diagnosis ◽  
Parotid Gland ◽  
Preoperative Diagnosis ◽  
Soft Mass ◽  
Parotid Region ◽  
Lipomatous Tumor ◽  
Parotid Tumors ◽  
Superficial Lobe ◽  
The Right

Lipomas are rarely found in the parotid gland region. Because of their rarity at this site, they are not often considered in the differential diagnosis of parotid tumors. The parotid lipoma is a slowly growing, asymptomatic, freely movable, soft mass. Preoperative diagnosis is generally difficult. We present a case of a slowly enlarging mass of the parotid region in a 44-year-old man that proved to be a lipomatous tumor of the parotid gland. We also review 42 other cases from the literature. Our patient's huge tumor was located in the superficial lobe of the gland, and a parotidectomy with preservation of the facial nerve was performed. There was no complication or recurrence of the tumor after a follow-up of 1 year.

Giant Pleomorphic Adenomas of Parotid Gland: a Case Series

2020 ◽  
Author(s):  
Yogendra Kumar Pareek ◽  
Deendayal Gupta ◽  
Yogesh Aseri ◽  
Digvijay Singh Rawat ◽  
Bhuvenesh K. Singh ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Case Series ◽  
Pleomorphic Adenomas

scholarly journals Recurrent Pleomorphic Adenomas of the Parotid Gland.

1992 ◽  
Vol 85 (11) ◽  
pp. 1787-1793
Author(s):  
Toshio Yamashita ◽  
Koichi Tomoda ◽  
Ghiyonori Ino ◽  
Toshio Yamawaki ◽  
Tadami Kumazawa
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenomas
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