Clinical activity of androgen deprivation therapy in patients with metastatic/relapsed androgen receptor-positive salivary gland cancers

Head & Neck ◽  
2015 ◽  
Vol 38 (5) ◽  
pp. 724-731 ◽  
Author(s):  
Laura D. Locati ◽  
Federica Perrone ◽  
Barbara Cortelazzi ◽  
Salvatore Lo Vullo ◽  
Paolo Bossi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Androgen Receptor ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation ◽  
Clinical Activity

scholarly journals Next-generation androgen receptor inhibitors in non-metastatic castration-resistant prostate cancer

2020 ◽  
Vol 12 ◽  
pp. 175883592097813
Author(s):  
Pernelle Lavaud ◽  
Clément Dumont ◽  
Constance Thibault ◽  
Laurence Albiges ◽  
Giulia Baciarello ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Overall Survival ◽  
Androgen Receptor ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation ◽  
Next Generation ◽  
Castration Resistant Prostate Cancer ◽  
Free Survival ◽  
Castration Resistant ◽  
Recent Advances

Until recently, continuing androgen deprivation therapy (ADT) and closely monitoring patients until evolution towards metastatic castration-resistant prostate cancer (CRPC) were recommended in men with non-metastatic CRPC (nmCRPC). Because delaying the development of metastases and symptoms in these patients is a major issue, several trials have investigated next-generation androgen receptor (AR) axis inhibitors such as apalutamide, darolutamide, and enzalutamide in this setting. This review summarizes the recent advances in the management of nmCRPC, highlighting the favourable impact of next-generation AR inhibitors on metastases-free survival, overall survival and other clinically meaningful endpoints.

P-109 Androgen deprivation therapy for salivary gland tumours: experience of a single institution

Oral Oncology ◽  
2021 ◽  
Vol 118 ◽  
pp. 3
Author(s):  
Carolina Pereira ◽  
Diana Pessoa ◽  
Miguel Rito ◽  
Teresa Alexandre ◽  
Isabel Sargento ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation ◽  
Single Institution ◽  
Salivary Gland Tumours

scholarly journals Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails

Oncogene ◽  
2010 ◽  
Vol 29 (25) ◽  
pp. 3593-3604 ◽  
Author(s):  
Y Niu ◽  
T-M Chang ◽  
S Yeh ◽  
W-L Ma ◽  
Y Z Wang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Androgen Receptor ◽  
Androgen Deprivation Therapy ◽  
Androgen Deprivation
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