Association between nutritional risk index and outcomes for head and neck cancer patients receiving concurrent chemo‐radiotherapy

Head & Neck ◽  
2020 ◽  
Vol 42 (9) ◽  
pp. 2560-2570
Author(s):  
Justin Oh ◽  
Alvin Liu ◽  
Eric Tran ◽  
Eric Berthelet ◽  
Jonn Wu ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Risk Index ◽  
Nutritional Risk ◽  
Nutritional Risk Index

Prognosis in Head and Neck Cancer: Importance of Nutritional and Biological Inflammatory Status

2021 ◽  
pp. 019459982110045
Author(s):  
Nicolas Saroul ◽  
Mathilde Puechmaille ◽  
Céline Lambert ◽  
Achraf Sayed Hassan ◽  
Julian Biau ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Prognostic Factors ◽  
Inflammatory Response ◽  
Nutritional Status ◽  
Head And Neck ◽  
Neck Cancer ◽  
Risk Index ◽  
Nutritional Risk ◽  
Inflammatory Status ◽  
Nutritional Risk Index

Objectives To determine the importance of nutritional status, social status, and inflammatory status in the prognosis of head and neck cancer. Study Design Single-center retrospective study of prospectively collected data. Setting Tertiary referral center. Methods Ninety-two consecutive patients newly diagnosed for cancer of the upper aerodigestive tract without metastases were assessed at time of diagnosis for several prognostic factors. Nutritional status was assessed by the nutritional risk index, social status by the EPICES score, and inflammatory status by the systemic inflammatory response index. The primary endpoint was overall survival. Results In multivariable analysis, the main prognostic factors were the TNM classification (hazard ratio [HR] = 3.34, P = .002, for stage T3-4), malnutrition as assessed by the nutritional risk index (HR = 3.64, P = .008, for severe malnutrition), and a systemic inflammatory response index score ≥1.6 (HR = 3.32, P = .02). Social deprivation was not a prognostic factor. Conclusion Prognosis in head and neck cancer is multifactorial; however, malnutrition and inflammation are important factors that are potentially reversible by early intervention.

The Geriatric Nutritional Risk Index as a Prognostic Factor in Patients with Advanced Head and Neck Cancer

2020 ◽  
Vol 131 (1) ◽  
Author(s):  
Masahiro Nakayama ◽  
Masahiko Gosho ◽  
Masahiro Adachi ◽  
Rieko Ii ◽  
Shin Matsumoto ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Prognostic Factor ◽  
Head And Neck ◽  
Neck Cancer ◽  
Risk Index ◽  
Nutritional Risk ◽  
Advanced Head ◽  
Geriatric Nutritional Risk Index ◽  
Nutritional Risk Index

NUTRITION ASSESSMENT IN HEAD AND NECK CANCER PATIENTS PRE and POST CHEMORADIOTHERAPY.

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Piyush Kumar ◽  
Bhavya P Pateneedi ◽  
Dharam P Singh ◽  
Arvind K Chauhan
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Nutritional Risk ◽  
Total Leukocyte Count ◽  
Risk Indicator ◽  
Anthropometric Parameters ◽  
Skin Fold Thickness ◽  
Before And After

INTRODUCTION: Head and neck cancer patients are frequently malnourished at the time of diagnosis and prior to the beginning of treatment. Deterioration of the nutritional status results in an increase in chemo radiotherapy related toxicity and this may increase the prolonged treatment time, which has been associated with poor clinical outcome. The present study aims to do nutritional assessment before and after chemo radiotherapy in head and neck cancer patients. MATERIAL AND METHODS: The present study was undertaken at the Department of Radiation Oncology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly. In this study, 50 patients of Head and neck tumours were enrolled and their nutrition was assessed before and after chemoradiotherapy. Nutrition assessment was done using different laboratory parameters like haemoglobin, total leukocyte count, blood urea, serum creatinine and serum bilirubin. Anthropometric parameters used are Body mass index, Skin fold thickness, and Mid-arm circumference. Nutritional risk indicator and PG-SGA score is measured before and after chemoradiotherapy. All the parameters were assessed and analysed using different statistical tests- Chi-square test, Fisher Exact test and paired t test.RESULTS: Haemoglobin decrease was statistically significant during treatment (p less than 0.001) and the decrease in total leukocyte count during treatment was showing trend towards significance (p value-0.056). There was deterioration in other parameters like blood urea, serum creatinine and serum bilirubin but was not statistically significant. Anthropometric parameters- Body mass index, mid-arm circumference and skin fold thickness and percent body fat showed a significant change (p less than 0.00001). Nutritional risk indicator and PG-SGA class has decreased for majority of patients during treatment, the change is statistically significant (p less than 0.00001 and p=0.0251) respectively.CONCLUSION: The nutrition has important role to play in the management of head and neck cancers by chemo radiotherapy. It helps to reduce the complications and improve the tolerance of chemo radiotherapy, thus avoiding treatment breaks which may lead to failure of treatment.

scholarly journals Nutritional risk and quality of life in head and neck cancer patients receiving chemoradiation

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
R Jean Hine ◽  
Allen Sherman ◽  
Eric Siegel ◽  
Jose A Penagaricano ◽  
Annemarie Maddox ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Nutritional Risk

NRS-2002 for pre-treatment nutritional risk screening and nutritional status assessment in head and neck cancer patients

2014 ◽  
Vol 23 (6) ◽  
pp. 1495-1502 ◽  
Author(s):  
Helena Orell-Kotikangas ◽  
Pia Österlund ◽  
Kauko Saarilahti ◽  
Paula Ravasco ◽  
Ursula Schwab ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Nutritional Status ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Nutritional Risk ◽  
Status Assessment ◽  
Nrs 2002 ◽  
Pre Treatment ◽  
Nutritional Risk Screening

Do Nutritional and Inflammatory Biomarkers Have Prognostic Significance in the Early Post Operative Period in Head and Neck Cancer? – A Pilot Study

2018 ◽  
Vol 55 (1) ◽  
pp. 79
Author(s):  
Nikhila Sham Sunder Bharadwaj ◽  
Ravi Nayar ◽  
Vishal Rao ◽  
Mehnanaz Fathima ◽  
Afrose Parveen
Keyword(s):  
Head And Neck Cancer ◽  
Pilot Study ◽  
Head And Neck ◽  
Neck Cancer ◽  
Risk Index ◽  
Prognostic Significance ◽  
Co Morbidity ◽  
Nutritional Risk Index ◽  
G Ratio ◽  
Tobacco Usage

This pilot study evaluated prognostic significance of patient/tumor factors and nutritional/inflammatory parameters with respect to the early post operative complications such as Wound Infection (WI) rates and Length of Hospital Stay (LOS) in 26 Head and Neck Cancer (HNC) surgical patients. The prognostic indices were calculated using patient and tumor related variables including age, sex, co-morbidity, tobacco usage, pathological diagnosis, hemoglobin (Hb) and albumin. The WI rate in the present study was found to be 30% and significantly correlated with both tobacco usage (p=0.021) and nutritional indices such as Albumin/ Globulin ratio (A/G) (p = 0.034) and Nutritional Risk Index (NRI) (p = 0.043). LOS (9.32 ± 2.719) was significantly correlated to Albumin levels (p = 0.002), A/G ratio (p = 0.02) and Prognostic Nutritional Index (PNI) (p = 0.006) and NRI (p = 0.002). This pilot study suggested that a positive history of tobacco usage and immune nutritional factors may influence early post-operative outcomes in head and neck surgery.

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