Evaluation and validation of Physiological and Operative Severity Score for the enumeration of mortality and morbidity and Portsmouth‐POSSUM scores in predicting morbidity and mortality in patients undergoing head and neck cancer surgeries

Head & Neck ◽  
2020 ◽  
Vol 42 (10) ◽  
pp. 2968-2974
Author(s):  
Nupur Karan ◽  
Suhail Siddiqui ◽  
Kailash S. Sharma ◽  
Gouri H. Pantvaidya ◽  
Jigeeshu V. Divatia ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Severity Score ◽  
Morbidity And Mortality ◽  
Mortality And Morbidity ◽  
Operative Severity Score

scholarly journals Nanoparticle-Based Chemotherapy Formulations for Head and Neck Cancer: A Systematic Review and Perspectives

Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1938
Author(s):  
Jefferson Muniz de Lima ◽  
Paulo Rogerio Bonan ◽  
Danyel Elias da Cruz Perez ◽  
Michael Hier ◽  
Moulay A. Alaoui-Jamali ◽  
...  
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Side Effects ◽  
Head And Neck ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Basic Research ◽  
Cochrane Central Register ◽  
Level Of Evidence ◽  
Mortality And Morbidity

Head and neck cancer (HNC) is a complex and heterogeneous disease associated with high mortality and morbidity worldwide. Standard therapeutic management of advanced HNC, which is based on radiotherapy often combined with chemotherapy, has been hampered by severe long-term side effects. To overcome these side effects, tumor-selective nanoparticles have been exploited as a potential drug delivery system to improve HNC therapy. A combination of MEDLINE, EMBASE, Cochrane Oral Health Group’s Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL) and ClinicalTrials.gov from inception up to June 2020 was used for this systematic review. A total of 1747 published manuscripts were reviewed and nine relevant references were retrieved for analysis, while eight of them were eligible for meta-analysis. Based on these studies, the level of evidence about the efficacy of nanoformulation for HNC therapy on tumor response and adverse side effects (SAE) was low. Even though basic research studies have revealed a greater promise of nanomaterial to improve the outcome of cancer therapy, none of them were translated into clinical benefits for HNC patients. This systematic review summarized and discussed the recent progress in the development of targeted nanoparticle approaches for HNC management, and open-up new avenues for future perspectives.

scholarly journals The role of infection in the morbidity and mortality of patients with head and neck cancer undergoing multimodality therapy

Cancer ◽  
1991 ◽  
Vol 67 (3) ◽  
pp. 716-721 ◽  
Author(s):  
Maha Hussain ◽  
Julie A. Kish ◽  
Lawrence Crane ◽  
Ahmed Uwayda ◽  
Glen Cummings ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Multimodality Therapy ◽  
Morbidity And Mortality

Management of vascular complications of head and neck cancer

2011 ◽  
Vol 126 (2) ◽  
pp. 111-115 ◽  
Author(s):  
J Rimmer ◽  
C E B Giddings ◽  
F Vaz ◽  
J Brooks ◽  
C Hopper
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Case Reports ◽  
High Risk Patient ◽  
Vascular Complications ◽  
Morbidity And Mortality ◽  
Illustrative Case ◽  
Life Threatening ◽  
Radiation Induced

AbstractBackground:Major vascular complications in patients with head and neck cancer have previously been thought of as terminal events. However, it is now possible to intervene in many situations, with benefits for quality of life as well as survival. Endovascular techniques have reduced morbidity and mortality in many situations, both emergency and elective.Method:We describe the techniques that can be employed in such situations, and present illustrative case reports. Life-threatening haemorrhage, carotid compression and radiation-induced carotid stenosis are all discussed.Conclusion:It is possible to predict where complications may arise, and to take prophylactic steps to allow treatment to continue. Early intervention can reduce both morbidity and mortality in this high-risk patient group.

Nutritional Assessment of the Head and Neck Cancer Patient

1980 ◽  
Vol 88 (6) ◽  
pp. 695-699 ◽  
Author(s):  
Matthew J. Lambert
Keyword(s):  
Radiation Therapy ◽  
Head And Neck Cancer ◽  
Cancer Patient ◽  
Head And Neck ◽  
Neck Cancer ◽  
Nutritional Support ◽  
Nutritional Assessment ◽  
Nutritional Deficiency ◽  
Neck Cancer Patient ◽  
Morbidity And Mortality

Malnutrition is a common problem in patients with head and neck cancer. Its presence may lead to an increase in morbidity and mortality following an operation, chemotherapy, and radiation therapy. A standard nutritional assessment will define the nature and degree of the nutritional deficiency while periodic reassessment will document the effects of nutritional support.

Prediction of mortality and morbidity in head and neck cancer patients 80 years of age and older undergoing surgery

2017 ◽  
Vol 128 (4) ◽  
pp. 871-877 ◽  
Author(s):  
Heidi E. L'Esperance ◽  
Dorina Kallogjeri ◽  
Shahnawaz Yousaf ◽  
Jay F. Piccirillo ◽  
Jason T. Rich
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Mortality And Morbidity ◽  
Prediction Of Mortality

scholarly journals Possible causes for delay in diagnosis and treatment in head and neck cancer: an institutional study

2018 ◽  
Vol 5 (6) ◽  
pp. 2291 ◽  
Author(s):  
Nikesh Agarwal ◽  
Daulat Singh ◽  
Manoj Verma ◽  
Shantunu Sharma ◽  
R. K. Spartacus ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Medical Consultation ◽  
Morbidity And Mortality ◽  
Diagnosis And Treatment ◽  
Medical Attention ◽  
Time Interval ◽  
Delay In Diagnosis

Background: Head and neck cancer is one of the leading cancers among Indian population. Early diagnosis and treatment is cornerstone for improving survival in any malignancy, any delay leads to advanced form of disease, leading to higher morbidity and mortality. Given the location, head and neck cancers are easily visible or palpable on clinical examination. In spite of this, many patients are diagnosed at advanced stage.Methods: A cross sectional observational study was conducted at a tertiary care center of western india including 156 newly diagnosed head and neck cancer patients. Delay in seeking medical attention was defined as time interval of more than 3 months from the first symptom recognition to the first medical consultation. Subjects were then divided into delay and non-delay group and compared to identify the factors associated with delay in seeking medical attention.Results: Delay in seeking medical consultation was seen in 109 (69.9%) patients. The factors found significantly associated with delay were older age (p<0.001), rural background (p<0.001), illiteracy (p<0.001), joint family (p<0.001), poor socioeconomic status (p<0.001), longer distance from hospital (p<0.001), tobacco chewing (p=0.018), insufficient knowledge (p<0.001) and fear (p=0.031) of the disease.Conclusions: Many of the identified factors for delay in seeking medical attention in head and neck cancer patients are amenable to improvement. Improving health coverage and awareness of available health services, specially in far rural areas could prevent delay in diagnosis and treatment and thus significantly reduce morbidity and mortality as well as burden on health system.

Surgical morbidity and mortality in patients after microvascular reconstruction for head and neck cancer

2017 ◽  
Vol 43 (2) ◽  
pp. 502-508 ◽  
Author(s):  
Y-H. Joo ◽  
K-J. Cho ◽  
J-O. Park ◽  
S-Y. Kim ◽  
M-S. Kim
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Morbidity And Mortality ◽  
Microvascular Reconstruction ◽  
Surgical Morbidity

Longitudinal Analysis of Morbidity and Mortality Conference Data for Head and Neck Cancer Patients

2013 ◽  
Vol 149 (2_suppl) ◽  
pp. P69-P69
Author(s):  
Stephen Y. Lai ◽  
Richa Rashmi ◽  
Carol M. Lewis ◽  
Amy C. Hessel ◽  
Paul W. Gidley ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Longitudinal Analysis ◽  
Morbidity And Mortality ◽  
Morbidity And Mortality Conference ◽  
Mortality Conference

Mortality and morbidity with intraoperative radiotherapy for head and neck cancer

1996 ◽  
Vol 17 (5) ◽  
pp. 308-310 ◽  
Author(s):  
Jeffrey R. Haller ◽  
Rodney E. Mountain ◽  
David E. Schuller ◽  
Subir Nag
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Intraoperative Radiotherapy ◽  
Mortality And Morbidity
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