scholarly journals Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network

Hepatology ◽  
2014 ◽  
Vol 60 (4) ◽  
pp. 1399-1408 ◽  
Author(s):  
Victor J. Navarro ◽  
Huiman Barnhart ◽  
Herbert L. Bonkovsky ◽  
Timothy Davern ◽  
Robert J. Fontana ◽  
...  
2021 ◽  
Vol 218 ◽  
pp. 108426
Author(s):  
Jawad Ahmad ◽  
Joseph A Odin ◽  
Paul H Hayashi ◽  
Robert J Fontana ◽  
Hari Conjeevaram ◽  
...  

Author(s):  
Diogo Costa Santos ◽  
Graça Lérias ◽  
Isabel Madruga

Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the Western world. In recent years, natural herbal and dietary supplements have become widely available to the general public and have increased in popularity. Reports of idiosyncratic liver injury caused by such supplements have also increased over the last decade. Horse chestnut is a herb used in dietary supplements primarily for complications of venous insufficiency. Clinically significant acute liver injury has been very rarely associated with its use. We present the case of a 70-year-old man with idiosyncratic horse chestnut-induced liver injury.


Digestion ◽  
2020 ◽  
pp. 1-4
Author(s):  
Sabine Weber ◽  
Grace L.H. Wong ◽  
Vincent W.S. Wong ◽  
Andreas Benesic ◽  
Henry L.Y. Chan ◽  
...  

2020 ◽  
Vol 24 (1) ◽  
pp. 141-155 ◽  
Author(s):  
Elizabeth Zheng ◽  
Naemat Sandhu ◽  
Victor Navarro

2019 ◽  
Vol 156 (6) ◽  
pp. S-1315
Author(s):  
Helgi K. Björnsson ◽  
Einar S. Björnsson ◽  
Ikhlas A. Khan ◽  
Bharathi Avula ◽  
Victor Navarro

2019 ◽  
Vol 18 (2) ◽  
pp. 201
Author(s):  
Mariana Porto Magalhaes ◽  
Raymundo Paraná ◽  
Genário Oliveira Santos Junior ◽  
Caio Gomes dos Santos Araújo ◽  
Vinicius Santos Nunes ◽  
...  

<strong>Background:</strong> Drug Induced Liver Injury (DILI) is responsible for wide spectrum of liver injury. Clinically, these events are presented in various forms and for reaching a different diagnosis other injury causes must be excluded. <strong>Aim:</strong> Identify and characterize cases of hepatotoxicity induced by drugs, herbal and dietary supplements in University Hospital in Brazil. <strong>Material and Methods: </strong>Observational and retrospective study. Was collected in records of University Hospital, between August 2009 at August 2014. The causality of the drug reactions suspected were evaluated Council for International Organizations of Medical Sciences (CIOMS). <strong>Results:</strong> We selected 30 suspected cases, 50% was female and average was 39 years. The therapeutic classes most common was: anti-infectives; antineoplastic agents; central nervous system drugs, anabolic steroid and herbal and dietary supplements (HDS). Cholestatic or mixed injury was observed in 73% these cases; 60% were highly probable, according to CIOMS.  <strong>Conclusion:</strong> DILI is caused by a wide variety of drugs, dietary supplements and dietary supplements. Anti-infectives and chemotherapy were responsible for much of the response


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