horse chestnut
Recently Published Documents


TOTAL DOCUMENTS

520
(FIVE YEARS 112)

H-INDEX

27
(FIVE YEARS 4)

2021 ◽  
Vol 8 (4) ◽  
pp. 333-335
Author(s):  
Hwa Yeon Yi ◽  
Jang Young Lee

Horse chestnut (Aesculus hippocastanum) is a common tree found on roads and parks. The shape of the fruit is very similar to that of the edible Korean chestnut (Castanea crenata); thus, people can eat it by mistake. However, reports of the side effects and toxicity from ingestion are very rare. A 46-year-old male who had no unusual findings in the past had eaten horse chestnut seed which he had mistaken to be Korean chestnut. He visited the emergency department (ED) with complaints of epigastric pain, nausea, and sweating. Blood tests showed a slight increase in the levels of liver enzymes, serum amylase, and pancreatic amylase. During the monitoring, he complained of palpitations, and electrocardiogram showed atrial fibrillation. On the following day after conservative treatment, blood testing and electrocardiogram showed normal findings. He was discharged from the ED as he did not complain of any further symptoms. When a patient who has eaten horse chestnut visits the ED, blood examination and electrocardiogram monitoring are needed, and conservative treatment is required.


2021 ◽  
Vol 14 (12) ◽  
pp. 1301
Author(s):  
Aleksandra Owczarek ◽  
Joanna Kołodziejczyk-Czepas ◽  
Paulina Marczuk ◽  
Julia Siwek ◽  
Katarzyna Wąsowicz ◽  
...  

Horse chestnut (Aesculus hippocastanum) flower is a traditional medicine applied to alleviate symptoms of chronic venous insufficiency (CVI). However, its flavonoid-based composition has not been sufficiently recognized, and the data supporting its traditional application are lacking. In the work, 43 constituents were detected by UHPLC–PDA–ESI–TQ–MS/MS (flavonoids, phenolic acids, flavanols, and coumarins), including 31 reported in the flower for the first time. The quantitative HPLC–PDA study (developed and validated for quality control purposes) indicated the fractionated extraction as an efficient method for enhancing the total polyphenol content (TPHC) in the extracts (up to 414.06 mg/g) and kaempferol glycosides as their dominant constituents (75.05–82.14% TPHC). The activity studies showed significant scavenging properties of the extracts and their constituents towards reactive oxygen species (especially against highly reactive hydroxyl radical, with capacities up to 7.85 mmol ascorbic acid equivalents/g). Moreover, the analytes relevantly protected human plasma biomolecules from peroxynitrite-induced oxidative/nitrative damage; at 1–50 µg/mL, they hindered the protein nitration and lipid peroxidation, decreasing the levels of 3-nitrotyrosine (by up to 50%) and thiobarbituric acid reactive substances (by up to 70%), respectively. The extracts also averted the depletion of plasma thiols (by up to 67%) and improved the non-enzymatic antioxidant capacity of plasma. The demonstrated mechanisms might be partly responsible for the efficacy of the flower in CVI. Additionally, the anti-aggregatory and anticoagulant properties of the extracts were found only mild or negligible, which suggests that they may be safely applied with drugs impacting the coagulation process.


Molecules ◽  
2021 ◽  
Vol 26 (22) ◽  
pp. 6856
Author(s):  
Sonya Tsibranska ◽  
Anela Ivanova ◽  
Slavka Tcholakova ◽  
Nikolai Denkov

The saponin escin, extracted from horse chestnut seeds, forms adsorption layers with high viscoelasticity and low gas permeability. Upon deformation, escin adsorption layers often feature surface wrinkles with characteristic wavelength. In previous studies, we investigated the origin of this behavior and found that the substantial surface elasticity of escin layers may be related to a specific combination of short-, medium-, and long-range attractive forces, leading to tight molecular packing in the layers. In the current study, we performed atomistic molecular dynamics simulations of 441 escin molecules in a dense adsorption layer with an area per molecule of 0.49 nm2. We found that the surfactant molecules are less submerged in water and adopt a more upright position when compared to the characteristics determined in our previous simulations with much smaller molecular models. The number of neighbouring molecules and their local orientation, however, remain similar in the different-size models. To maintain their preferred mutual orientation, the escin molecules segregate into well-ordered domains and spontaneously form wrinkled layers. The same specific interactions (H-bonds, dipole–dipole attraction, and intermediate strong attraction) define the complex internal structure and the undulations of the layers. The analysis of the layer properties reveals a characteristic wrinkle wavelength related to the surface lateral dimensions, in qualitative agreement with the phenomenological description of thin elastic sheets.


Processes ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1838
Author(s):  
Thomas Havelt ◽  
Sarah Brettschneider ◽  
Michaela Schmitz

Different analyses and feasibility studies have been conducted on the plant extracts of thyme (Thymus vulgaris), European horse chestnut (Aesculus hippocastanum), Nordmann fir (Abies nordmanniana), and snowdrop (Galanthus elwesii) to evaluate bio-based alternatives to common petrol-based stabilisers. For this purpose, in this study, plant extracts were incorporated into poly-lactic acid films (PLA) at different concentrations. The films’ UV absorbance and migration into packed food was analysed via photometric assays (ABTS radical cation scavenging capacity assay, β-carotene assay) and GC–MS analysis. Furthermore, the synergistic antioxidant effects of various combinations of extracts and isolated active compounds were determined. This way, antioxidant effects can be increased, allowing for a highly effective use of resources. All extracts were successfully incorporated into PLA films and showed notable photoabsorbing effects, while no migration risk was observed. Depending on extract combinations, high synergistic effects of up to 726% can be utilised to improve the effectiveness of bio-based extracts. This applies particularly to tomato paste and Aesculus hippocastanum extracts, which overall show high synergistic and antioxidant effects in combination with each other and with isolated active compounds. The study shows that it is possible to create safe bio-based antioxidant films which show even improved properties when using highlighted target combinations.


2021 ◽  
Vol 33 (SP1) ◽  
pp. 137-149
Author(s):  
Syed Insha Rafiq ◽  
Khalid Muzaffar ◽  
Syed Mansha Rafiq ◽  
DC Saxena ◽  
BN Dar

There has been a growing demand for the production of gluten-free products due to increased occurrence of celiac disease. Thus, different research groups have been investigating the use of various available materials for the development of these functional products to fulfill customer’s needs. Horse Chestnut (Aesculus indica) seeds are underutilized, low-cost, and gluten-free, found in hilly areas of the Himalayan region of Kashmir valley, India. To determine their potential as an alternative to conventional food grains, an investigation was conducted to determine the physicochemical, functional, pasting, and thermal properties of Horse Chestnut (HCN) flour and its compatibility for the development of gluten-free pasta. HCN flour comprised 73.34% carbohydrate, 11.36% protein, 6.34% crude fiber, 3.27% fat, 3.16% ash, 3.15g/g oil absorption capacity, and 4.65% water absorption index. HCN flour showed 505 cp peak, 354 cp trough, 151 cp breakdown, 472 cp final viscosity, and 66.05°C pasting temperature. Transition temperatures (onset, peak, and conclusion) and enthalpy change (ΔH) were 60.12°C, 69.90°C, 81.53°C, and 10.56 J/g, respectively. Pasta prepared from HCN flour using guar gum (0, 0.5, and 1%) was analyzed for color, cooking qualities, and textural and sensory analysis. The present results showed that HCN flour possesses good nutritional quality and has properties comparable to conventional wheat flour. Therefore, HCN-flour-based pasta can act as a nutritious alternative to conventional gluten-free pasta and add variety to the diet of people suffering from celiac disease.


2021 ◽  
pp. 115-122
Author(s):  
Luiza Bakhtiyarovna Azimova ◽  
Al'bina Vasil'yevna Filatova ◽  
Abbaskhan Sabirkhanovich Turaev ◽  
Djalol Turgunbaevich Djurabaev

This paper presents the results of a study of the polysaccharide complex, first obtained using microwave radiation from the shells of horse chestnut seeds (Aesculus Hippocastanum L.), collected on the territory of the Tashkent region of the Republic of Uzbekistan. It is shown that the use of microwave waves makes it possible to intensify the method of obtaining polysaccharides with an increase in their yield. The yield of the obtained product reaches 13%, compared with the method of obtaining without using microwave radiation (9.85%), which indicates the prospects of using microwave radiation in the isolation of polysaccharides from this type of raw material. The molecular weight characteristics were determined, and using GC/MS analysis of trimethylsilyl derivatives, the monosaccharide composition of the complex isolated from the shells of the Semyon chestnut by alkaline extraction was established. It was found that the isolated polysaccharides consist mainly of arabinose and galactose residues (65–100%), and also, as minor monosaccharides, up to 35% of glucose, xylose, mannose, rhamnose, ribose residues. Signals and absorption bands corresponding to total polysaccharides were observed in 13C NMR and IR spectra. The NMR analysis data are consistent with the results of the analysis of the monosaccharide composition of the polysaccharide complex obtained using GC / MS. The antiradical activity of the polysaccharide complex has been established.


Sign in / Sign up

Export Citation Format

Share Document