Effect of metabolic syndrome on cardiovascular, hepatic events, and death in chronic hepatitis B patients: Methodological issues

Hepatology ◽  
2017 ◽  
Vol 65 (5) ◽  
pp. 1779-1780 ◽  
Author(s):  
Erfan Ayubi ◽  
Saeid Safiri ◽  
Mohadeseh Sani ◽  
Amin Doosti-Irani ◽  
Ali Sanjari Moghaddam
2020 ◽  
Vol 158 (6) ◽  
pp. S-1291
Author(s):  
Karen J. Campoverde Reyes ◽  
Javier Eduardo Guevara Alvarez ◽  
Kamolyut Lapumnuaypol ◽  
Pir A. Shah ◽  
satinder p. kaur ◽  
...  

2022 ◽  
Author(s):  
Khin Naing Thin ◽  
Andrew Tran ◽  
Jie Li ◽  
Eunice Yewon Lee ◽  
Hongli Yang ◽  
...  

Introduction: Chronic hepatitis B (CHB) patients with metabolic syndrome (MetS) may present increased risk of liver-related outcomes (LROs) but prior studies were limited by small sample size and/or conflicting results. Using a systematic review and meta-analytic approach, we aimed to determine the association between MetS and LROs in CHB. Methods: Two researchers independently screened studies from the PubMed, Embase, Web of Science, and Cochrane Library databases from inception to January 21, 2020 and extracted the data. Estimates were pooled using a random-effects model. Results: We screened 2,228 articles and included 10 eligible studies (18,360 CHB patients, 2,557 with MetS). MetS was significantly associated with LROs overall (OR=2.45, 95%CI=1.39-4.32) but not the individual LRO components but subgroup analyses were limited by small study numbers. Discussion/Conclusion: MetS is associated with almost 3 folds higher risk of LROs in CHB and should be considered in management decisions. However, additional studies are needed.


Gut ◽  
2010 ◽  
Vol 59 (2) ◽  
pp. 277.1-277
Author(s):  
Henry Lik-Yuen Chan ◽  
Grace Lai-Hung Wong ◽  
Vincent Wai-Sun Wong

Gut ◽  
2010 ◽  
Vol 59 (2) ◽  
pp. 276-277 ◽  
Author(s):  
Li-Chun Chang ◽  
Chen-Shuan Chung ◽  
Chun-Jen Liu ◽  
Jia-Horng Kao

2020 ◽  
Vol 158 (6) ◽  
pp. S-1274
Author(s):  
He Qiu ◽  
Michelle Shi ◽  
Diana Wee ◽  
Sohum A. Patwa ◽  
Tai-Ping Lee

Hepatology ◽  
2016 ◽  
Vol 64 (5) ◽  
pp. 1507-1517 ◽  
Author(s):  
Jenny Yeuk-Ki Cheng ◽  
Vincent Wai-Sun Wong ◽  
Yee-Kit Tse ◽  
Angel Mei-Ling Chim ◽  
Henry Lik-Yuen Chan ◽  
...  

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