Prevalence of H. Pylori Infection in Non-Cirrhotic Patients with Chronic Delta Hepatitis

Objective: The relationship between Hepatitis Delta infection and Helicobacter infection in patients with non-cirrhotic hepatitis B infection was retrospectively investigated. Material and Methods: Stool samples of 117 patients included with Delta hepatitis infection in the study At total 36 of them were tested for H. Pylori infection. To detect H. Pylori, stool samples were tested using a commercial stool H. Pylori antigen assay. Results: Of these, 13 (19%) patients had H. Pylori seropositivity in the Hepatitis B infection group and 23 (48%) patients tested positive for H. Pylori infection in hepatitis delta infection group. There was a statistically significant difference between groups regarding H. Pylori seropositivity by the faecal test (p= 0.001). Conclusion: This study provides new knowledge on H. Pylori infection and reflects the need for evidence-based and comorbid dieases-oriented guidelines in the field of gastroenterology.

Viral neuromyopathy associated with acute hepatitis B infection

Viral myositis is commonly seen with influenza and COVID-19 infections. While it has been described with acute viral hepatitis, concomitant involvement of the peripheral nerves causing a neuromyopathy has not been reported. A 67-year-old man with acute hepatitis B infection developed a severe myalgia and lower limb weakness around 1 month into his illness. Investigations revealed a neuromyopathy and rhabdomyolysis. MRI whole body with short tau inversion recovery sequences showed scattered muscle hyperintensities in the upper and lower limbs. He was treated with intravenous immunoglobulin and improved. This is the first report of an acute neuromyopathy associated with acute hepatitis B viral infection and demonstration of muscle MRI abnormalities in this condition.

Hepatitis B-Associated Symptomatic Iron Overload, with Complete Resolution after Nucleoside Analogue Treatment

Symptomatic iron overload and hyperferritinemia are rarely mentioned as complications of chronic hepatitis B infection. We report a case of a 70-year-old woman who presented with symptoms of iron overload including aches in the calves, fatigue, poor appetite, and low mood. Laboratory results showed a serum ferritin of 2449 μg/L and transferrin saturation of 74%. Her symptoms completely resolved with hepatitis B antiviral treatment. Serum ferritin and transferrin saturation also normalized. Symptomatic iron overload is a rare yet clinically important complication that can result from chronic hepatitis B infection.

Assessment of Knowledge, Attitude, and Practice to Wards Hepatitis B Prevention Among Debre Tabor Health Science College Students, South Gondar, Amhara, Ethiopia 2021

BACKGROUND: Hepatitis B infection is caused by the hepatitis B virus which attacks the liver and can cause both acute and chronic disease and puts people at high risk of death from cirrhosis and liver cancer. Hepatitis B virus (HBV) is a highly contagious virus which is 50-100 times more infectious than HIV but have similar mode of transmission. Hepatitis B is the most common serious liver infection in the world. Hepatitis B infection is one of the major public health problems and is the tenth leading cause of death. OBJECTIVES: The aim of this study is to assess knowledge, attitude, and practice towards hepatitis B prevention among students in Debre Tabor Health Science College. METHODS: A cross-sectional study was conducted among 422 health science students in Debre tabor, town September to october,2021. The study participants were selected using a simple random sampling technique after proportionally allocating the sample size from the total number of students, and finally study subjects was selected by systematic random sampling based on their list studying at Debre tabor health science college. The data were collected by trained data collectors using a structured self-questionnaire. The collected data were checked, coded and entered to SPSS version 20, and for data cleaning and analysis. RESULT: The response rate was 84.1% (n = 355). A total of 262(73.8%) of the students knew about the transmission of HBV infection. Majority of the students (73.5%) agreed for vaccination against HBV infection. About 10.4%, 16.3%, 5.6%, 15.5%, 10.4%, 5.1%, and 5.07% of were responds know wearing of gloves, wearing of goggles, adequate disposal of sharp materials, avoid patients diagnosed with hepatitis B, multivitamin/Blood Tonic, use antibiotics after contact, and other protective measures taken to protect against hepatitis B infection students knew about the preventive measures against HBV infection. CONCLUSION: The overall awareness regarding HBV disease was found to be deficient among the health science students.

Hepatitis B Virus Infection and Intrahepatic Cholestasis during Pregnancy: Review and Management

Hepatitis B Infection (HBV), one of the major epidemics in China, has an impact on mother-to-child transmission. In addition, a number of existing studies have shown that there is a correlation between HBV infection and pregnancy complications and adverse pregnancy outcomes.