scholarly journals Dental metal hypersensitivity in patients with psoriasis vulgaris: A case‐control study using an in vitro quantitative sensitivity test

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Yasunari Kageyama ◽  
Koichi Aida ◽  
Kimihiko Kawauchi ◽  
Masafumi Morimoto ◽  
Tetsu Akiyama ◽  
...  
Keyword(s):  
Psoriasis Vulgaris ◽  
Case Control Study ◽  
Case Control ◽  
Sensitivity Test ◽  
Metal Hypersensitivity ◽  
Dental Metal ◽  
Control Study

The Identification and Significance of a Thr→Pro Polymorphism in Kringle IV Type 8 of Apolipoprotein(a)

1997 ◽  
Vol 77 (05) ◽  
pp. 0949-0954 ◽  
Author(s):  
J Prins ◽  
F R Lues ◽  
Y Y van der Hoek ◽  
J J.P Kastelein ◽  
B N Bouma ◽  
...  
Keyword(s):  
Case Control Study ◽  
Amino Acid Position ◽  
Case Control ◽  
Binding Studies ◽  
Binding Characteristics ◽  
Apolipoprotein A ◽  
Significant Independent Risk Factor ◽  
And Gender ◽  
Control Study

SummaryElevated plasma levels of lipoprotein(a) [Lp(a)] represent a significant independent risk factor for the development of atherosclerosis. Interindividual levels of apo(a) vary over 1000-fold and are mainly due to inheritance that is linked to the locus of the apolipoprotein(a) [apo(a)] gene. The apo(a) gene encodes multiple repeats of a sequence exhibiting up to 85% DNA sequence homology with plasminogen kringle IV (K.IV), a lysine binding domain. In our search for sequence polymorphisms in the K.IV coding domain, we identified a polymorphism predicting a Thr→Pro substitution located at amino acid position 12 of kringle IV type 8 of apo(a). The functional and clinical significance of this polymorphism was analysed in a case-control study and by comparing the in vitro lysine binding characteristics of the two Lp(a) subtypes.The case-control study (involving 153 subjects having symptomatic atherosclerosis and 153 age and gender matched normolipidemic controls) revealed an overall allele frequency for the Thr12-→Pro substitution in kringle IV type 8 of 14% and a negative association between presence of the Pro12-subtype and symptomatic atherosclerosis (p <0.03). The in vitro lysine binding studies, using Lp(a) isolated from subjects homozygous for either Thr12 or Pro12 in K.IV type 8, revealed comparable lysine-Sepharose binding fractions for the two subtypes. The binding affinity (Kd) for immobilised plasmin degraded des- AA-fibrin (DesafibTM-X) was also comparable for the two subtypes, however a decreased maximal attainable binding (Bmax) for immobilised desafibTM-X was observed for the Pro12-subtype Lp(a).

scholarly journals Comparing four laboratory three-parent techniques to construct human aged non-surrounded nucleolus germinal vesicle oocytes: A case-control study

2020 ◽  
Author(s):  
Sara Darbandi ◽  
Mahsa Darbandi ◽  
Ashok Agarwal ◽  
Hamid Reza Khorram khorshid ◽  
Mohammad Reza Sadeghi ◽  
...  
Keyword(s):  
Case Control Study ◽  
Germinal Vesicle ◽  
Oocyte Donation ◽  
Case Control ◽  
Assisted Reproductive Technique ◽  
Oocyte Competence ◽  
Reproductive Techniques ◽  
Developmental Capacity ◽  
Control Study

Background: The three-parent assisted reproductive technique may increase oocyte competence. Objective: In this case-control study, the suitability of germinal vesicle transfer (GVT), synchronous ooplasmic transfer (sOT), asynchronous ooplasmic transfer using cryopreserved MII oocyte (caOT), and asynchronous ooplasmic transfer using waste MII oocyte (waOT) for maturation of the human-aged non-surrounded nucleolus germinal vesicle-stage (NSN-GV) oocyte were investigated. Materials and Methods: NSN-GV oocytes were subjected to four methods: group A (GVT), B (sOT), C (caOT) D (waOT), and E (Control). The fusion rates, MI, MII, ICSI observations and cleavage at 2-cell, 4-cell, and 8-cell stages were compared in the groups. Results: In GVT, none of the oocytes fused. In sOT, all oocytes fused, 20 achieved the MI, 14 progressed to MII, 8 fertilized, 6 cleaved and 5, 4, and 3 achieved the 2- cells, 4-cells and 8-cells, respectively. In caOT, all oocytes fused and achieved the MI, 8 progressed to MII and fertilized, 6 cleaved and 6, 5, and 5 achieved the 2-cells, 4- cells, and 8-cells respectively. In waOT, all oocytes fused, 5 and 3 progressed to MI and MII, respectively, but only one fertilized, cleaved and reached a 4-cells stage. In group E, 6 and 2 oocytes progressed to MI and MII, respectively, and only one fertilized but arrested at the zygote stage. caOT had the highest survival rate when compared to sOT (p = 0.04), waOT (p = 0.002), and control (p = 0.001). Conclusion: The caOT method was beneficial over sOT, waOT, and GVT in supplementing the developmental capacity of human-aged NSN-GV oocytes. Key words: Assisted reproductive techniques, In vitro oocyte maturation techniques, Nuclear transfer techniques, Oocytes, Oocyte donation.

PREGNANCY OUTCOMES after IN VITRO FERTILIZATION FOR MODERATE AND SEVERE endometriosis. A CASE-CONTROL STUDY.

2021 ◽  
pp. 102274
Author(s):  
Edouard Ribot ◽  
Julie Berbis ◽  
Ilyes Hamouda ◽  
Daniel Cohen ◽  
Aubert Agostini ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Pregnancy Outcomes ◽  
Case Control Study ◽  
Case Control ◽  
Vitro Fertilization ◽  
Control Study

scholarly journals Dehydroepiandrosterone supplementation in women undergoing assisted reproductive technology with poor ovarian response. A prospective case-control study

2017 ◽  
Vol 46 (1) ◽  
pp. 143-149 ◽  
Author(s):  
Haifa A. Al-Turki
Keyword(s):  
Pregnancy Rate ◽  
Live Birth ◽  
Case Control Study ◽  
Ovarian Response ◽  
Case Control ◽  
Poor Ovarian Response ◽  
Control Study ◽  
Prospective Case Control Study

Objective The effects of dehydroepiandrosterone (DHEA) supplementation in Saudi Arabian women with poor ovarian response (POR) is presently unknown. The present study aimed to assess the benefits of DHEA supplementation in women undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). Methods This was a prospective case-control study involving 62 women who were diagnosed with POR and underwent IVF/ICSI between January 2012 and June 2016. The positive influence of DHEA in 34 women, compared with 28 women without supplementation, was defined as improvements in the number of oocytes retrieved, the fertilization rate, the number of grade I embryos generated and the pregnancy rate. Results Both groups were evenly matched for age, body mass index and laboratory test parameters. There were statistically significant differences between the groups with and without DHEA supplementation for oocyte yield (6.35 ± 2.41 versus 3.98 ± 3.2), Grade I embryos generated (55% versus 30%), positive pregnancy rate (21/34 versus 10/28), and live birth rate (18/34 versus 4/28). Conclusion DHEA supplementation in women with POR had a positive effect on hormonal profiles, the quality of the endometrium, the number of oocytes retrieved, the quality of embryos, and the pregnancy and live birth rates.

In vitro fertilization when men, women, or both partners are positive for HIV: a case–control study

2017 ◽  
Vol 295 (6) ◽  
pp. 1493-1507 ◽  
Author(s):  
Pauline Vankerkem ◽  
Yannick Manigart ◽  
Annick Delvigne ◽  
Lieveke Ameye ◽  
Deborah Konopnicki ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Case Control Study ◽  
Case Control ◽  
Vitro Fertilization ◽  
Control Study

Two consecutive singleton pregnancies versus one twins pregnancy as preferred outcome of in vitro fertilization for mothers and infants: a retrospective case–control study

2016 ◽  
Vol 32 (4) ◽  
pp. 687-692 ◽  
Author(s):  
Giovanni Battista La Sala ◽  
Daria Morini ◽  
Salvatore Gizzo ◽  
Alessia Nicoli ◽  
Stefano Palomba
Keyword(s):  
In Vitro Fertilization ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Vitro Fertilization ◽  
Control Study ◽  
Singleton Pregnancies

In Vitro Maturation Potential of Monocyte-Derived Dendritic Cells Is Impaired in Patients With Spinal Cord Injury: A Case-Control Study

2005 ◽  
Vol 86 (5) ◽  
pp. 974-978 ◽  
Author(s):  
Sung-Ching Pan ◽  
Szu-Min Hsieh ◽  
Yen-Ho Wang ◽  
Bor-Luen Chiang ◽  
Tien-Shang Huang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Dendritic Cells ◽  
In Vitro Maturation ◽  
Case Control Study ◽  
Case Control ◽  
Cord Injury ◽  
Control Study
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