Dental metal hypersensitivity in patients with psoriasis vulgaris: A case‐control study using an
            in vitro
            quantitative sensitivity test

SummaryElevated plasma levels of lipoprotein(a) [Lp(a)] represent a significant independent risk factor for the development of atherosclerosis. Interindividual levels of apo(a) vary over 1000-fold and are mainly due to inheritance that is linked to the locus of the apolipoprotein(a) [apo(a)] gene. The apo(a) gene encodes multiple repeats of a sequence exhibiting up to 85% DNA sequence homology with plasminogen kringle IV (K.IV), a lysine binding domain. In our search for sequence polymorphisms in the K.IV coding domain, we identified a polymorphism predicting a Thr→Pro substitution located at amino acid position 12 of kringle IV type 8 of apo(a). The functional and clinical significance of this polymorphism was analysed in a case-control study and by comparing the in vitro lysine binding characteristics of the two Lp(a) subtypes.The case-control study (involving 153 subjects having symptomatic atherosclerosis and 153 age and gender matched normolipidemic controls) revealed an overall allele frequency for the Thr12-→Pro substitution in kringle IV type 8 of 14% and a negative association between presence of the Pro12-subtype and symptomatic atherosclerosis (p <0.03). The in vitro lysine binding studies, using Lp(a) isolated from subjects homozygous for either Thr12 or Pro12 in K.IV type 8, revealed comparable lysine-Sepharose binding fractions for the two subtypes. The binding affinity (Kd) for immobilised plasmin degraded des- AA-fibrin (DesafibTM-X) was also comparable for the two subtypes, however a decreased maximal attainable binding (Bmax) for immobilised desafibTM-X was observed for the Pro12-subtype Lp(a).

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Results from a case-control study comparing mean aneuploidy rates and pregnancy outcomes in women with and without endometriosis undergoing In Vitro Fertilization (IVF) cycles

10.26226/morressier.5af300af738ab10027aa9559 ◽

2018 ◽

Author(s):

Roberta Venturella ◽

Danilo Cimadomo ◽

Laura Francesca Rienzi

Keyword(s):

In Vitro Fertilization ◽

Pregnancy Outcomes ◽

Case Control Study ◽

Case Control ◽

Vitro Fertilization ◽

Control Study

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The relationship between urinary phthalate metabolites and polycystic ovary syndrome in women undergoing in vitro fertilization: Nested case-control study

Chemosphere ◽

10.1016/j.chemosphere.2021.131495 ◽

2021 ◽

pp. 131495

Author(s):

Iman Al-Saleh

Keyword(s):

In Vitro Fertilization ◽

Case Control Study ◽

Polycystic Ovary ◽

Case Control ◽

Ovary Syndrome ◽

Vitro Fertilization ◽

Nested Case Control ◽

The Relationship ◽

Control Study

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Comparing four laboratory three-parent techniques to construct human aged non-surrounded nucleolus germinal vesicle oocytes: A case-control study

International Journal of Reproductive BioMedicine ◽

10.18502/ijrm.v13i6.7284 ◽

2020 ◽

Author(s):

Sara Darbandi ◽

Mahsa Darbandi ◽

Ashok Agarwal ◽

Hamid Reza Khorram khorshid ◽

Mohammad Reza Sadeghi ◽

...

Keyword(s):

Case Control Study ◽

Germinal Vesicle ◽

Oocyte Donation ◽

Case Control ◽

Assisted Reproductive Technique ◽

Oocyte Competence ◽

Reproductive Techniques ◽

Developmental Capacity ◽

Control Study

Background: The three-parent assisted reproductive technique may increase oocyte competence. Objective: In this case-control study, the suitability of germinal vesicle transfer (GVT), synchronous ooplasmic transfer (sOT), asynchronous ooplasmic transfer using cryopreserved MII oocyte (caOT), and asynchronous ooplasmic transfer using waste MII oocyte (waOT) for maturation of the human-aged non-surrounded nucleolus germinal vesicle-stage (NSN-GV) oocyte were investigated. Materials and Methods: NSN-GV oocytes were subjected to four methods: group A (GVT), B (sOT), C (caOT) D (waOT), and E (Control). The fusion rates, MI, MII, ICSI observations and cleavage at 2-cell, 4-cell, and 8-cell stages were compared in the groups. Results: In GVT, none of the oocytes fused. In sOT, all oocytes fused, 20 achieved the MI, 14 progressed to MII, 8 fertilized, 6 cleaved and 5, 4, and 3 achieved the 2- cells, 4-cells and 8-cells, respectively. In caOT, all oocytes fused and achieved the MI, 8 progressed to MII and fertilized, 6 cleaved and 6, 5, and 5 achieved the 2-cells, 4- cells, and 8-cells respectively. In waOT, all oocytes fused, 5 and 3 progressed to MI and MII, respectively, but only one fertilized, cleaved and reached a 4-cells stage. In group E, 6 and 2 oocytes progressed to MI and MII, respectively, and only one fertilized but arrested at the zygote stage. caOT had the highest survival rate when compared to sOT (p = 0.04), waOT (p = 0.002), and control (p = 0.001). Conclusion: The caOT method was beneficial over sOT, waOT, and GVT in supplementing the developmental capacity of human-aged NSN-GV oocytes. Key words: Assisted reproductive techniques, In vitro oocyte maturation techniques, Nuclear transfer techniques, Oocytes, Oocyte donation.

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PREGNANCY OUTCOMES after IN VITRO FERTILIZATION FOR MODERATE AND SEVERE endometriosis. A CASE-CONTROL STUDY.

Journal of Gynecology Obstetrics and Human Reproduction ◽

10.1016/j.jogoh.2021.102274 ◽

2021 ◽

pp. 102274

Author(s):

Edouard Ribot ◽

Julie Berbis ◽

Ilyes Hamouda ◽

Daniel Cohen ◽

Aubert Agostini ◽

...

Keyword(s):

In Vitro Fertilization ◽

Pregnancy Outcomes ◽

Case Control Study ◽

Case Control ◽

Vitro Fertilization ◽

Control Study

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In Vitro Thrombotic Tendency of Reactive Thrombocytosis in Critically Ill Patients: A Prospective Case-control Study

Anaesthesia and Intensive Care ◽

10.1177/0310057x1204000313 ◽

2012 ◽

Vol 40 (3) ◽

pp. 472-478 ◽

Cited By ~ 14

Author(s):

O. C. Duff* ◽

K. M. Ho ◽

S. M. Maybury

Keyword(s):

Critically Ill ◽

Critically Ill Patients ◽

Case Control Study ◽

Case Control ◽

Reactive Thrombocytosis ◽

Thrombotic Tendency ◽

Control Study ◽

Prospective Case Control Study

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Dehydroepiandrosterone supplementation in women undergoing assisted reproductive technology with poor ovarian response. A prospective case-control study

Journal of International Medical Research ◽

10.1177/0300060517720005 ◽

2017 ◽

Vol 46 (1) ◽

pp. 143-149 ◽

Cited By ~ 5

Author(s):

Haifa A. Al-Turki

Keyword(s):

Pregnancy Rate ◽

Live Birth ◽

Case Control Study ◽

Ovarian Response ◽

Case Control ◽

Poor Ovarian Response ◽

Control Study ◽

Prospective Case Control Study

Objective The effects of dehydroepiandrosterone (DHEA) supplementation in Saudi Arabian women with poor ovarian response (POR) is presently unknown. The present study aimed to assess the benefits of DHEA supplementation in women undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). Methods This was a prospective case-control study involving 62 women who were diagnosed with POR and underwent IVF/ICSI between January 2012 and June 2016. The positive influence of DHEA in 34 women, compared with 28 women without supplementation, was defined as improvements in the number of oocytes retrieved, the fertilization rate, the number of grade I embryos generated and the pregnancy rate. Results Both groups were evenly matched for age, body mass index and laboratory test parameters. There were statistically significant differences between the groups with and without DHEA supplementation for oocyte yield (6.35 ± 2.41 versus 3.98 ± 3.2), Grade I embryos generated (55% versus 30%), positive pregnancy rate (21/34 versus 10/28), and live birth rate (18/34 versus 4/28). Conclusion DHEA supplementation in women with POR had a positive effect on hormonal profiles, the quality of the endometrium, the number of oocytes retrieved, the quality of embryos, and the pregnancy and live birth rates.

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