The pitfalls of the dexamethasone suppression test: A biological marker of endogenous depression?

1987 ◽  
Vol 2 (2) ◽  
pp. 85-103 ◽  
Author(s):  
H. E. Klein ◽  
M. Berger
1983 ◽  
Vol 12 (2) ◽  
pp. 103-108 ◽  
Author(s):  
William H. Nelson ◽  
William W. Orr ◽  
Carl R. Sullivan

The dexamethasone suppression test (DST) appears to be a sensitive and specific biological marker for endogenous depression that can have important diagnostic and treatment implications. The authors present three case studies of patients treated on a combined medicine-psychiatric inpatient unit, and who presented with complex psychobiological illnesses. They discuss the usefulness of the DST in the hospital management of these patients from a diagnostic and treatment perspective.


1985 ◽  
Vol 72 (2) ◽  
pp. 166-171 ◽  
Author(s):  
H. M. A. S. Standish-Barry ◽  
A. S. Hale ◽  
A. Honig ◽  
N. Bouras ◽  
P. K. Bridges ◽  
...  

1983 ◽  
Vol 67 (4) ◽  
pp. 258-264 ◽  
Author(s):  
H. Aggernses ◽  
C. Kirkegaard ◽  
I. Krog-Meyer ◽  
B. Kijne ◽  
J. K. Larsen ◽  
...  

1984 ◽  
Vol 6 (1) ◽  
pp. 33-42 ◽  
Author(s):  
M.Toscano Aguilar ◽  
M. Lemaire ◽  
P. Castro ◽  
M. Libotte ◽  
J. Reynders ◽  
...  

1984 ◽  
Vol 18 (4) ◽  
pp. 374-377 ◽  
Author(s):  
H. A. Whiteford ◽  
Larry Evans

The tricyclic antidepressants and the monoamine oxidase inhibitors have been shown to be effective in the treatment of some patients with phobic and panic disorders. To explain this action it has been suggested that a number of these patients may have an atypical biological depression. In an attempt to test this hypothesis we used the dexamethasone suppression test (DST), which has been proposed as a state dependent biological marker of depression. We compared the non-suppression rate of agoraphobic patients suffering panic attacks with controls and with patients suffering major depression. Twenty-nine per cent of the agoraphobics showed non-suppression compared with 12% of the control group and 64% of the depressives.


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