Use of a Trypsin, Peru Balsam, and Castor Oil Spray on the Oral Mucosa: Case Report and Review of the Literature

We describe an extraordinary case of a nevus of Ota with intraoral mucosal involvement. We performed a selective review of the English literature and discuss the potential malignant behavior when the oral mucosa is involved.

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Multiple Second Primary Oral Squamous Cell Carcinomas in a Nonsmoker and Nondrinker Woman: Case Report and Review of the Literature

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-1684 ◽

2015 ◽

Vol 16 (4) ◽

pp. 322-328 ◽

Cited By ~ 2

Author(s):

Maria Luiza Diniz de Sousa Lopes ◽

Ana Rafaela Luz de Aquino ◽

Maria de Lourdes Silva de Arruda Morais ◽

Lélia Bristo de Medeiros ◽

Éricka Janine Dantas da Silveira

Keyword(s):

Case Report ◽

Oral Mucosa ◽

Squamous Cell ◽

Unusual Case ◽

Squamous Cell Carcinomas ◽

Second Primary ◽

Review Of The Literature ◽

Oral Squamous Cell Carcinomas ◽

Diagnosis And Management

ABSTRACT Aim This manuscript aims to describe an unusual case of multiple second primary squamous cell carcinomas (SCCs) in several sites of the oral mucosa in a nonsmoker and nondrinker woman and to discuss the diagnostic criteria, clinicopathological aspects and outcome of second primary tumor (SPT). Background Patients treated for SCC of the head and neck are at high risk for developing SPT arising from the same dysplastic mucosal field. Currently, there is no reliable method to predict which of the patients will develop SPT. Case description A 64-year-old nonsmoker and nondrinker woman developed several second primary oral SCCs in 7 years of follow-up, most of them being synchronic, treated by surgery without and with chemotherapy and radiotherapy. Conclusion Patients treated for SCC require a long-term and careful follow-up as the development of SPT contributes with significantly negative impact on the prognosis. Clinical significance This report describes the diagnosis and management of a very unusual case of several SPTs affecting different sites of the oral mucosa in the same patient. Moreover, the patient had no apparent risk factors associated with the development of the oral cancer. Therefore, a brief update concerning SPT and its diagnosis and management is also provided. How to cite this article de Sousa Lopes MLD, de Aquino ARL, de Arruda Morais MLS, de Medeiros LB, da Silveira EJD. Multiple Second Primary Oral Squamous Cell Carcinomas in a Nonsmoker and Nondrinker Woman: Case Report and Review of the Literature. J Contemp Dent Pract 2015;16(4):322-328.

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Scleral Discoloration Because of Minocycline Use: A Case Report and Review of the Literature

Military Medicine ◽

10.1093/milmed/usab208 ◽

2021 ◽

Author(s):

Yasmin F.K. Islam ◽

Erich P. Horn

Keyword(s):

Case Report ◽

Tympanic Membrane ◽

Oral Mucosa ◽

Older Patients ◽

Vision Loss ◽

Subcutaneous Fat ◽

Review Of The Literature ◽

Younger Patients ◽

Medical Comorbidities

ABSTRACT In this case report, we highlight minocycline-induced scleral hyperpigmentation, combined with ear and fingernail discoloration that developed after over 15 years of use for rosacea in a 78-year-old male with multiple medical comorbidities. Minocycline, a tetracycline antibiotic, is used to treat rosacea and acne as well as some orthopedic infections. It is typically used for extended periods of time; long-term use of minocycline is associated with hyperpigmentation of the sclera, conjunctiva, retina, teeth, skin, subcutaneous fat, oral mucosa, tympanic membrane, and gingiva. This case highlights that hyperpigmentation is more likely to occur in older patients than in younger patients. Scleral hyperpigmentation is not associated with vision loss; however, cosmetic concerns can prompt discontinuation of minocycline. Nonetheless, after cessation, the lesions persist in some patients. Monitoring for hyperpigmentation in patients using minocycline is important, as the hyperpigmentation is more likely to be permanent with long-term use.

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