Chronic ethanol exposure increasesgoosecoid(GSC) expression in human embryonic carcinoma cell differentiation

2013 ◽  
Vol 34 (1) ◽  
pp. 66-75 ◽  
Author(s):  
Debasish Halder ◽  
Ji Hyun Park ◽  
Mi Ran Choi ◽  
Jin Choul Chai ◽  
Young Seek Lee ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Carcinoma Cell ◽  
Ethanol Exposure ◽  
Chronic Ethanol ◽  
Chronic Ethanol Exposure ◽  
Embryonic Carcinoma ◽  
Embryonic Carcinoma Cell ◽  
Human Embryonic Carcinoma Cell

DMRT-1 expression during NEC8 human embryonic carcinoma cell differentiation

2006 ◽  
Vol 97 (4) ◽  
pp. 277-282 ◽  
Author(s):  
Hitoshi Koji ◽  
Akira Yamada ◽  
Toshihiko Nagasawa ◽  
Shinobu Gamou
Keyword(s):  
Cell Differentiation ◽  
Carcinoma Cell ◽  
Embryonic Carcinoma ◽  
Embryonic Carcinoma Cell ◽  
Human Embryonic Carcinoma Cell

scholarly journals Retinoic Acid Induces Differentiation of Mouse F9 Embryonic Carcinoma Cell by Modulating the miR-485 Targeting of Abhd2

2019 ◽  
Vol 20 (9) ◽  
pp. 2071 ◽  
Author(s):  
Mengying Yu ◽  
Lei Zhang ◽  
Yingxiang Liu ◽  
Defu Liu ◽  
Zekun Guo
Keyword(s):  
Retinoic Acid ◽  
Cell Differentiation ◽  
Carcinoma Cell ◽  
Carcinoma Cells ◽  
Extracellular Signal Regulated Kinase ◽  
Embryonic Carcinoma ◽  
Extracellular Signal ◽  
Embryonic Carcinoma Cells ◽  
Embryonic Carcinoma Cell ◽  
Mediate Cell

Retinoic acid (RA) plays a key role in pluripotent cell differentiation. In F9 embryonic carcinoma cells, RA can induce differentiation towards somatic lineages via the Ras-extracellular signal-regulated kinase (Ras/Erk) pathway, but the mechanism through which it induces the Erk1/2 phosphorylation is unclear. Here, we show that miR-485 is a positive regulator that targets α/β-hydrolase domain-containing protein 2 (Abhd2), which can result in Erk1/2 phosphorylation and triggers differentiation. RA up-regulates miR-485 and concurrently down-regulates Abhd2. We verified that Abhd2 is targeted by miR-485 and they both can influence the phosphorylation of Erk1/2. In summary, RA can mediate cell differentiation by phosphorylating Erk1/2 via miR-485 and Abhd2.

Chronic ethanol exposure induces alterations in the nucleocytoplasmic transport in growing astrocytes

2008 ◽  
Vol 106 (4) ◽  
pp. 1914-1928 ◽  
Author(s):  
María Pilar Marín ◽  
Mónica Tomas ◽  
Guillermo Esteban-Pretel ◽  
Luis Megías ◽  
Carmen López-Iglesias ◽  
...  
Keyword(s):  
Nucleocytoplasmic Transport ◽  
Ethanol Exposure ◽  
Chronic Ethanol ◽  
Chronic Ethanol Exposure
Sign in / Sign up

Export Citation Format

Share Document