scholarly journals Tunable methacrylated hyaluronic acid‐based hydrogels as scaffolds for soft tissue engineering applications

2019 ◽  
Vol 108 (2) ◽  
pp. 279-291 ◽  
Author(s):  
Benjamin S. Spearman ◽  
Nikunj K. Agrawal ◽  
Andrés Rubiano ◽  
Chelsey S. Simmons ◽  
Sahba Mobini ◽  
...  
2020 ◽  
Vol 11 (1) ◽  
pp. 8424-8430

Hydrogels are cross-linked three-dimensional (3D) polymeric network, which can hold the water within its porous structure. They have recently been used in various biomedical applications. In this study, injectable hyaluronic acid (HA) hydrogels were prepared using different concentrations of 1,4-butanediol diglycidyl ether (BDDE) as a crosslinker (1-5% w/w) and investigated their rheological, swelling and injectability properties. The results demonstrated that the rheological characteristics of hydrogels enhanced with increasing crosslinker concentration. The elastic modulus of the hydrogels ranged from 280 Pa to 990 Pa, while the complex viscosities were found between 42 Pa.s and 190 Pa.s at an oscillation frequency of 1 Hz. These results clearly suggest that the injectable HA hydrogels are a potential candidate for various soft tissue engineering applications due to their highly tunable rheological properties.


2007 ◽  
Vol 8 (9) ◽  
pp. 2739-2745 ◽  
Author(s):  
Eva Wisse ◽  
Raymond A. E. Renken ◽  
Jorg R. Roosma ◽  
Anja R. A. Palmans ◽  
E. W. Meijer

2017 ◽  
Vol 46 (3) ◽  
pp. 637-649 ◽  
Author(s):  
Nupur Kumar ◽  
Dayananda Desagani ◽  
Girish Chandran ◽  
Narendra Nath Ghosh ◽  
Ganesh Karthikeyan ◽  
...  

2017 ◽  
Vol 195 ◽  
pp. 10-13 ◽  
Author(s):  
Poulami Basu ◽  
Alexandros Repanas ◽  
Anamika Chatterjee ◽  
Birgit Glasmacher ◽  
U. NarendraKumar ◽  
...  

RSC Advances ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 482-490 ◽  
Author(s):  
Lucila Navarro ◽  
Roque J. Minari ◽  
Santiago E. Vaillard

Elastomeric poly-ester materials have extraordinary potential for soft tissue engineering applications.


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