Active poly(ADPribose) metabolism in DNAase- and salt-resistant rat testis chromatin with high transcriptional activity/competence

2003 ◽  
Vol 89 (4) ◽  
pp. 688-697 ◽  
Author(s):  
Maria Rosaria Faraone Mennella ◽  
Guglielmo Roma ◽  
Benedetta Farina
mSystems ◽  
2021 ◽  
Author(s):  
Anh D. Ha ◽  
Mohammad Moniruzzaman ◽  
Frank O. Aylward

The discovery of giant viruses has transformed our understanding of viral complexity. Although viruses have traditionally been viewed as filterable infectious agents that lack metabolism, giant viruses can reach sizes rivalling cellular lineages and possess genomes encoding central metabolic processes.


1983 ◽  
Vol 11 (9) ◽  
pp. 2551-2562 ◽  
Author(s):  
J.P. Goddard ◽  
M. Squire ◽  
M Bienz ◽  
J.D. Smith

1999 ◽  
Vol 19 (5) ◽  
pp. 3904-3915 ◽  
Author(s):  
Edward E. Schmidt ◽  
Eric S. Hanson ◽  
Mario R. Capecchi

ABSTRACT During mammalian spermatogenesis, meiosis is followed by a brief period of high transcriptional activity. At this time a large amount of mRNA is stored as messenger ribonucleoprotein (mRNP) particles. All subsequent processes of sperm maturation occur in the complete absence of transcription, primarily using proteins which are newly synthesized from these stored mRNAs. By expressing transgene mRNAs in the early haploid spermatids of mice, we have investigated the sequence requirements for determining whether specific mRNAs in these cells will be stored as mRNP particles or be assembled into polysomes. The results suggest that mRNAs which are transcribed in spermatids are assembled into mRNP particles by a mechanism that acts independently of mRNA sequence. Our findings reveal a fundamental similarity between the mechanisms of translational control used in spermatogenesis and oogenesis.


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