Circular RNA circ‐Foxo3 inhibits esophageal squamous cell cancer progression via the miR‐23a/PTEN axis

2019 ◽  
Vol 121 (3) ◽  
pp. 2595-2605 ◽  
Author(s):  
Yao Xing ◽  
Wen‐Juan Zha ◽  
Xiao‐Min Li ◽  
Hao Li ◽  
Fei Gao ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Circular Rna ◽  
Esophageal Squamous Cell Cancer

scholarly journals Circular RNA circ-LRP6 facilitates Myc-driven tumorigenesis in esophageal squamous cell cancer

Bioengineered ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 932-938
Author(s):  
Jiayang Wang ◽  
Weiguo Zhu ◽  
Guangzhou Tao ◽  
Wanwei Wang
Keyword(s):  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Circular Rna ◽  
Esophageal Squamous Cell Cancer

scholarly journals Expression of p14ARF, p15INK4b, p16INK4a and skp2 increases during esophageal squamous cell cancer progression

2012 ◽  
Vol 3 (6) ◽  
pp. 1026-1032 ◽  
Author(s):  
PENG BAI ◽  
XUE XIAO ◽  
JUAN ZOU ◽  
LIN CUI ◽  
TRI M. BUI NGUYEN ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Esophageal Squamous Cell Cancer

CircRNA hsa_circ_0004771 promotes esophageal squamous cell cancer progression via miR-339-5p/CDC25A axis

Epigenomics ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 587-603 ◽  
Author(s):  
Enmin Huang ◽  
Junhui Fu ◽  
Qiuyan Yu ◽  
Peixin Xie ◽  
Zhongxian Yang ◽  
...  
Keyword(s):  
Cancer Progression ◽  
Squamous Cell ◽  
Squamous Cell Cancer ◽  
Cell Cancer ◽  
Tumor Burden ◽  
Esophageal Squamous Cell Cancer ◽  
Regulatory Relationship ◽  
Pair Plasma

Aim: The role of circRNAs in esophageal squamous cell cancer (ESCC) remains unclear. Materials & methods: Here we profiled six pair plasma circRNA in ESCC based on RNA sequencing, and then verified the elevation of hsa_circ_0004771 in 20 cancer tissues and 105 pair case–control plasma samples by quantitative reverse transcriptase PCR. Results: The upregulation of hsa_circ_0004771 was correlated with heavier tumor burden and poor prognosis, knockdown of it inhibited the ESCC cells proliferation both in vitro and in vivo. Mechanistically, hsa_circ_0004771 positively regulated CDC25A by acting as a molecular sponge of miR-339-5p and rescue assay confirmed this regulatory relationship. Conclusion: These results suggested that hsa_circ_0004771 can serve as a general less-invasive biomarker and may provide diagnostic and prognostic value in carcinoma.

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