Simultaneous Kinetic-Spectrophotometric Determination of Nb(V) and Ta(V) Using H-Point Standard Addition Method

2006 ◽  
Vol 53 (5) ◽  
pp. 995-1003 ◽  
Author(s):  
Abbas Afkhami ◽  
Ali Reza Zarei
2004 ◽  
Vol 148 (3-4) ◽  
pp. 259-265 ◽  
Author(s):  
Jahanbakhsh Ghasemi ◽  
Soodabe Seifi ◽  
Mozafar Sharifi ◽  
Rostam Ghorbani ◽  
Ali Amini

2021 ◽  
pp. 77-85

Simultaneous spectrophotometric determination of captopril and hydro-chlorothiazide in pharmaceutical formulations by the H-point standard addition method (HPSAM) is described. Absorbance at 211.5 and 230.3 nm was monitored upon the addition of standard solutions of captopril. The results showed that in prepared mixtures, captopril and hydrochlorothiazide can be determined simultaneously at concentration ratios varying from 1.0:0.8 to 2.5:1.5 μg/mL, respectively. Percentage recovery was found to be 95.33–104.37% for captopril and 96.8–105% for hydrochlorothiazide, with a relative standard deviation (RSD) of 2.46%. The method was successfully used to evaluate the antihypertensive captopril drug in a binary combination of hydrochlorothiazide in real samples with high precision and accuracy within the recovery percentage.


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