Microwave assisted L‐proline catalyzed
One‐Pot Three‐Component
Reaction for the synthesis of
4‐aminoaryl‐2‐phenyl‐2H
‐3‐nitrochromene hybrid via Domino
Michael‐Henry‐Michael
addition reaction
Microwave supported, water intervened, nano crystalline TiO2 catalyzed synthesis of 3-(1,5-dioxo-1,5-diphenylpentan-3-yl)quinolin-2(1H)-ones, is described.
A convenient method for synthesizing 3-amino-1,5-benzodiazepine-2-one via the Michael addition reaction of o-phenylenediamine with dehydroalanine ester derivatives, followed by cyclization, was developed. This simple method was used to obtain a variety of N-substituted 3-amino-1,5-benzodiazepine-2-ones in one pot with good yields.