Racemic synthesis of 2′-substituted nicotine analogs

Journal of Heterocyclic Chemistry ◽

10.1002/jhet.841 ◽

2011 ◽

Vol 49 (1) ◽

pp. 161-166 ◽

Author(s):

Anne Rouchaud ◽

William R. Kem

Keyword(s):

Nicotine Analogs

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Active Transport of High-Affinity Choline and Nicotine Analogs into the Central Nervous System by the Blood-Brain Barrier Choline Transporter

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.102.045856 ◽

2002 ◽

Vol 304 (3) ◽

pp. 1268-1274 ◽

Author(s):

David D. Allen ◽

Paul R. Lockman ◽

Karen E. Roder ◽

Linda P. Dwoskin ◽

Peter A. Crooks

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Blood Brain Barrier ◽

Active Transport ◽

Brain Barrier ◽

Choline Transporter ◽

High Affinity ◽

Blood Brain ◽

The Central Nervous System ◽

Nicotine Analogs

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Enantiomeric resolution and chiral recognition of racemic nicotine and nicotine analogs by .beta.-cyclodextrin complexation. Structure-enantiomeric resolution relationships in host-guest interactions

Analytical Chemistry ◽

10.1021/ac00170a027 ◽

1988 ◽

Vol 60 (19) ◽

pp. 2120-2127 ◽

Author(s):

Jeffrey I. Seeman ◽

Henry V. Secor ◽

Daniel W. Armstrong ◽

Karen D. Timmons ◽

Timothy J. Ward

Keyword(s):

Chiral Recognition ◽

Enantiomeric Resolution ◽

Beta Cyclodextrin ◽

Cyclodextrin Complexation ◽

Nicotine Analogs

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Functional diversity among 5-substituted nicotine analogs; in vitro and in vivo investigations

European Journal of Pharmacology ◽

10.1016/s0014-2999(01)01570-9 ◽

2002 ◽

Vol 435 (2-3) ◽

pp. 171-180 ◽

Author(s):

Małgorzata Dukat ◽

Imad M Damaj ◽

Richard Young ◽

Robert Vann ◽

Allan C Collins ◽

...

Keyword(s):

Functional Diversity ◽

Nicotine Analogs

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Binding free energies for nicotine analogs inhibiting cytochrome P450 2A6 by a combined use of molecular dynamics simulations and QM/MM-PBSA calculations

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.02.037 ◽

2014 ◽

Vol 22 (7) ◽

pp. 2149-2156 ◽

Author(s):

Haiting Lu ◽

Xiaoqin Huang ◽

Mohamed Diwan M. AbdulHameed ◽

Chang-Guo Zhan

Keyword(s):

Molecular Dynamics ◽

Cytochrome P450 ◽

Molecular Dynamics Simulations ◽

Free Energies ◽

Combined Use ◽

Cytochrome P450 2A6 ◽

Dynamics Simulations ◽

Nicotine Analogs ◽

Binding Free Energies

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Effects of nicotine analogs in an experimental model of Parkinson´s disease: role of CDK5 on dopamine release

Frontiers in Cellular Neuroscience ◽

10.3389/conf.fncel.2015.35.00009 ◽

2015 ◽

Vol 9 ◽

Author(s):

Gonzalez Yeimy ◽

Barreto George E.

Keyword(s):

Experimental Model ◽

Dopamine Release ◽

Nicotine Analogs

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Formamidines as α-amino carbanion precursors. The synthesis of 2-arylpiperidines, -pyrrolidines, and nicotine analogs

Tetrahedron Letters ◽

10.1016/s0040-4039(00)98247-9 ◽

1985 ◽

Vol 26 (48) ◽

pp. 5863-5866 ◽

Author(s):

A.I. Meyers ◽

Jeffrey M. Marra

Keyword(s):

Nicotine Analogs

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Pyrrolidine-Substituted Nicotine Analogs: Synthesis and Pharmacology

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600590314 ◽

1970 ◽

Vol 59 (3) ◽

pp. 342-344 ◽

Author(s):

Warren Hankins ◽

Alfred Burger

Keyword(s):

Nicotine Analogs

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Synthesis and Evaluation of Nicotine Analogs as Neuronal Nicotinic Acetylcholine Receptor Ligands

Journal of Medicinal Chemistry ◽

10.1021/jm00047a012 ◽

1994 ◽

Vol 37 (21) ◽

pp. 3542-3553 ◽

Author(s):

Nan-Horng Lin ◽

George M. Carrera ◽

David J. Anderson

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Receptor Ligands ◽

Nicotinic Acetylcholine ◽

Nicotine Analogs

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Structure-activity relationships for nicotine analogs comparing competition for [3H]nicotine binding and psychotropic potency

Drug Development Research ◽

10.1002/(sici)1098-2299(199809)45:1<10::aid-ddr2>3.0.co;2-g ◽

1998 ◽

Vol 45 (1) ◽

pp. 10-16 ◽

Author(s):

David X. Wang ◽

Heather Booth ◽

Nicole Lerner-Marmarosh ◽

Thomas S. Osdene ◽

Leo G. Abood

Keyword(s):

Structure Activity Relationships ◽

Structure Activity ◽

Nicotine Analogs

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Optically active nicotine analogs. Synthesis of (S)-(-)-2,5-dihydro-1-methyl-2-(3-pyridyl)pyrrole ((S)-(-)-3',4'-dehydronicotine)

The Journal of Organic Chemistry ◽

10.1021/jo00157a029 ◽

1983 ◽

Vol 48 (9) ◽

pp. 1529-1531 ◽

Author(s):

Charles G. Chavdarian

Keyword(s):

Optically Active ◽

Nicotine Analogs

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