High prevalence of mixed genotype infections in hepatitis B virus infected intravenous drug users

2004 ◽  
Vol 74 (4) ◽  
pp. 536-542 ◽  
Author(s):  
Bing-Fang Chen ◽  
Pei-Jer Chen ◽  
Guey-Mei Jow ◽  
Erwin Sablon ◽  
Chun-Jen Liu ◽  
...  
2007 ◽  
Vol 79 (11) ◽  
pp. 1674-1678 ◽  
Author(s):  
Chih-Lin Lin ◽  
Chun-Jen Liu ◽  
Pei-Jer Chen ◽  
Ming-Yang Lai ◽  
Ding-Shinn Chen ◽  
...  

2001 ◽  
Vol 13 (11) ◽  
pp. 1347-1354 ◽  
Author(s):  
M. Santolamazza ◽  
M. Delle Monache ◽  
A. Alvino ◽  
M. Bacosi ◽  
S. D'Innocenzo ◽  
...  

1991 ◽  
Vol 163 (4) ◽  
pp. 923-923 ◽  
Author(s):  
P. Mezzelani ◽  
L. Venturini ◽  
G. Turrina ◽  
F. Lugoboni ◽  
D. C. Des Jarlais

Author(s):  
Ghafran Ali ◽  
Kanza Ashfaq

Hepatitis-B,C,HIV and TB among intravenous drug users continues to be a serious explanation for disease and death, this study was conducted to survey the prevalence of Hepatitis-B,C,HIV and TB in rehabilitation center of Punjab, Pakistan. A telephonic and visited survey of 78 rehabilitation centers in Punjab Pakistan to assess their treatment. An analysis of 21 responded that returned useable data revealed that only 7.2% patients of responded rehabilitation centers are positive for HEP-B. 33.23% patients are positive for HEP-C, 8.74% patients are positive for HIV and 0.87% patients are positive for TB. Majority of the respondent of whom doctors, psychologists believe that the patient, partner of the patient and their children should be offered for HEP-B,C,HIV and TB screening regularly.


2020 ◽  
Author(s):  
Fazle Rabbi Chowdhury ◽  
Anna L McNaughton ◽  
Mohammad Robed Amin ◽  
Lovely Barai ◽  
Mili Rani Saha ◽  
...  

ABSTRACTBangladesh is one of the world’s top ten burdened countries for viral hepatitis. We investigated an adult fever cohort (n=201) recruited in Dhaka, to determine the prevalence of hepatitis B virus (HBV) infection and to identify cases of occult hepatitis B infection (OBI). HBV exposure (anti-HBc) was documented in 72/201 (36%), and active HBV infection in 16/201 (8%), among whom 3 were defined as OBI (defined as detectable HBV DNA but negative HBsAg). Applying a target-enrichment sequencing pipeline to samples with HBV DNA >3.0log10 IU/ml, we obtained deep whole genome sequences for four cases, identifying genotypes A, C and D. Polymorphisms in the surface gene of the OBI case may account for the negative HBsAg status. We identified mutations associated with nucleos(t)ide analogue resistance, although the clinical significance in this cohort is not known. The high prevalence of HBV in this setting highlights the benefits of offering screening in hospital patients and the importance of HBV DNA testing of transfusion products to reduce the risk of transmission. In order to work towards international Sustainable Development Goal targets for HBV elimination, increased investment is required for diagnosis, treatment and prevention in Bangladesh.


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