From the Discovery of Extremozymes to an Enzymatic Product: Roadmap Based on Their Applications

With the advent of the industrial revolution, the use of toxic compounds has grown exponentially, leading to a considerable pollution of the environment. Consequently, the development of more environmentally conscious technologies is an urgent need. Industrial biocatalysis appears as one potential solution, where a higher demand for more robust enzymes aims to replace toxic chemical catalysts. To date, most of the commercially available enzymes are of mesophilic origin, displaying optimal activity in narrow ranges of temperature and pH (i.e., between 20°C and 45°C, neutral pH), limiting their actual application under industrial reaction settings, where they usually underperform, requiring larger quantities to compensate loss of activity. In order to obtain novel biocatalysts better suited for industrial conditions, an efficient solution is to take advantage of nature by searching and discovering enzymes from extremophiles. These microorganisms and their macromolecules have already adapted to thrive in environments that present extreme physicochemical conditions. Hence, extremophilic enzymes stand out for showing higher activity, stability, and robustness than their mesophilic counterparts, being able to carry out reactions at nonstandard conditions. In this brief research report we describe three examples to illustrate a stepwise strategy for the development and production of commercial extremozymes, including a catalase from an Antarctic psychrotolerant microorganism, a laccase from a thermoalkaliphilic bacterium isolated from a hot spring and an amine-transaminase from a thermophilic bacterium isolated from a geothermal site in Antarctica. We will also explore some of their interesting biotechnological applications and comparisons with commercial enzymes.

A Biographic Researcher in Pursuit of an Aesthetic: The use of arts-based (re)presentations in “performative” dissemination of life stories

The (re)presentation of biographic narrative research benefits greatly from embracing the art of its craft. This requires a renewed interest in an aesthetic of storytelling. Where do we find an aesthetic in which to base our new “performative” social science? The 20th Century was not kind to 18th Century notions of what truth and beauty mean. The terms need to be re-examined from a local, quotidian vantage point, with concepts such as “aesthetic judgment” located within community. Social Constructionism asks us to participate in alterior systems of belief and value. The principles of Nicolas Bourriaud’s Relational Aesthetics offer one possible set of convictions for further exploration. Relational Art is located in human interactions and their social contexts. Central to it are inter-subjectivity, being-together, the encounter and the collective elaboration of meaning, based in models of sociability, meetings, events, collaborations, games, festivals and places of conviviality. Bourriaud believes that Art is made of the same material as social exchanges. If social exchanges are the same as Art, how can we portray them? One place to start is in our (re)presentations of narrative stories, through publications, presentations and performances. Arts-based (re)presentation in knowledge diffusion in the post-modern era is explored as one theoretical grounding for thinking across epistemologies and supporting inter-disciplinary efforts. An example from my own published narrative biography work is described, adding credence to the concept of the research report/presentation as a “dynamic vehicle”, pointing to ways in which biographic sociology can benefit from work outside sociology and, in turn, identifying areas of possible collaboration with the narrator in producing “performances” within published texts themselves.

An Autoethnographic Report on the Use and Impact of Social Networking Sites as an Approach to Teaching of the Research Process

The establishment of the K-12 curriculum has had a significant impact on subject requirements related to the outcome-based education plan and the requisite output for a given research report or requirement. Social networking platforms enable students to effortlessly complete a variety of tasks, such as learning and performance. By intervening in research, social networking sites break down the barriers that limit both students and teachers in the research process. Three methodologies or ideas have arisen, known as approaches, that could help you facilitate teaching research, even if you are not in the research discipline: the Facebook-Personality Network Approach, the Virtual Research Journal, and the Google Immersion Approach. It is considered favorably by some students and users, but there are those who take advantage of its negative aspects. Instead of focusing on the emerging ideas or topics created by coding, I used social networking sites to demonstrate that research can be done anytime, anyplace, for any purpose or cause. According to the outcome-based education paradigm, students found the three techniques highly engaging. In order to be a teacher-researcher, you must utilize your originality and resourcefulness when it comes to all of the resources, devices, and technology, as well as the available social networking sites.

CONCEPTUAL UNDERSTANDING OF TRANSVERSE MYELITIS IN AYURVEDA: A CRITICAL REVIEW

Transverse myelitis (TM) is a rare neurological disease of spinal cord inflammation. Onslaught inflammation damage the myelin is leading to nervous system scaring. Consequently, the patient presents devastating neurological effects. It can afflict people of any age, gender or race. Symptoms per usual evolve over hours or days and then deteriorate over days to weeks. Symptoms include pain, sensory problems, weakness in the legs and arms, and bladder and bowel problems. Most people partially recover within three months; others may be permanently disabled. There is no cure for TM thus far, but neurological deficit can be minimised. From the purview of Ayurveda, TM can be categorised under the spectrum of Vata disorder. Recent research report the successful treatment of TM. However, each explains the pathology differently. This review will discuss the concepts of TM apropos to Mishravarana (combined occlusion) and its management. We suggest that symptoms and pathology of TM simulate closely with Avaranajanya Vatavyadi (disease of Vata due to occlusion). Mishravarana (combined occlusion) illustrates the complexity of the disease process involved.

ENGLISH FOR MARKET RESEARCH REPORT WRITING: COURSE DESIGN

At undergraduate and postgraduate levels in business schools, lecturers often provide students with a suggested structure for a market research report assignment. Thereafter, the students are left to independently master the appropriate register and the technique of writing for this genre. While many students may learn to be good at business studies, they might fall short in writing despite having to produce several reports at university level. One of the reasons for this shortfall may be that some of the students may lack the confidence to produce reports which meet academic or professional standards in the English language. A short English for Specific Purposes (ESP) course that addresses the technical writing needs of business students as an option or add-on course to undergraduate and postgraduate business curricula could provide the simple solution. It could even be formalised as a credit bearing course to motivate students to undertake it.With a view to the above, as a pilot ESP module, a 15-hour English for Market Research Report Writing Skills course was designed to try and meet the specific needs of undergraduate market research students at the Warwick Business School (WBS). It was intended to be taught under the auspices of the Warwick Skills Certificate Programme at the University of Warwick in the United Kingdom (UK).

Notes on policing, racism and the Covid-19 pandemic in the UK

This commentary excerpts from the research report ‘A threat to public safety: policing, racism and the Covid-19 pandemic’, carried out by the Centre on the Dynamics of Ethnicity (CoDE) and published by the Institute of Race Relations in September 2021. One of the only pieces of research based on the experiences of the policed and their testimonies, the report suggests that policing during the Covid-19 pandemic undermines public health measures whilst disproportionately targeting Black and Minority Ethnic communities in the UK. The authors raise concerns about the policing of the pandemic and show that racially minoritised communities have been most harshly affected – being more likely to be stopped by the police, threatened or subject to police violence and falsely accused of rule-breaking and wrong-doing. The report argues that lockdown conditions, new police powers, and histories of institutionally racist policing have combined to pose a threat to already over-policed communities and the most marginalised and vulnerable sections of society.